Christian O’Reilly received his B.Ing. (electrical eng.; 2007), his M.Sc.A. (biomedical eng.; 2011), and his Ph.D. (biomedical eng.; 2012) from Polytechnique Montreal, where he worked to apply pattern recognition and machine learning to predict brain stroke risks. He was later a postdoctoral fellow at the Center for Advanced Research in Sleep Medicine of the Hôpital du Sacré-Coeur/Université de Montréal (2012–2014) and then a NSERC postdoctoral fellow at McGill's Brain Imaging Center (2014–2015), where he worked on characterizing EEG sleep transients. During this period, he also was a visiting scholar in Pr. K. Friston's laboratory at the University College of London to study effective connectivity during sleep transients using Dynamic Causal Modelling. He later took on a six-month fellowship on functional connectivity in autism, after which he moved to Switzerland to work for the internationally renowned Blue Brain project (EPFL; 2015–2018), where he led the project on large-scale biophysically detailed modelling of the thalamocortical loop. In 2020, he resumed his work on functional connectivity in autism as a research associate at McGill. Since 2021, Christian has joined the Department of Computer Science and Engineering, the Artificial Intelligence Institute, the Institute for Mind and Brain, and the Carolina Autism and Neurodevelopmental Research Center at the University of South Carolina as an assistant professor in neuroscience and artificial intelligence.