Breast cancer is one of the most common causes of cancer-related death in women worldwide. Early and accurate diagnosis of breast cancer may significantly increase the survival rate of patients. In this study, we aim to develop a fully automatic, deep learning-based, method using descriptor features extracted by Deep Convolutional Neural Network (DCNN) models and pooling operation for the classification of hematoxylin and eosin stain (H#E) histological breast cancer images provided as a part of the International Conference on Image Analysis and Recognition (ICIAR) 2018 Grand Challenge on BreAst Cancer Histology (BACH) Images. Different data augmentation methods are applied to optimize the DCNN performance. We also investigated the efficacy of different stain normalization methods as a pre-processing step. The proposed network architecture using a pre-trained Xception model yields 92.50% average classification accuracy.
Automatic detection of leukemic B-lymphoblast cancer in microscopic images is very challenging due to the complicated nature of histopathological structures. To tackle this issue, an automatic and robust diagnostic system is required for early detection and treatment. In this paper, an automated deep learning-based method is proposed to distinguish between immature leukemic blasts and normal cells. The proposed deep learning based hybrid method, which is enriched by different data augmentation techniques, is able to extract high-level features from input images. Results demonstrate that the proposed model yields better prediction than individual models for Leukemic Blymphoblast classification with 96.17% overall accuracy, 95.17% sensitivity and 98.58% specificity. Fusing the features extracted from intermediate layers, our approach has the potential to improve the overall classification performance.
1 March 2022 in International Journal of Medical Informatics
In recent years, the advancement in modern technologies has not only resulted in an explosion of huge data sets being captured and recorded in different fields, but also given rise to concerns in the security and protection of data during storage, transmission, processing, and access. The blockchain is a distributed ledger that records transactions in a secure, flexible, verifiable and permanent way. Transactions in a blockchain can be an exchange of an asset, the execution of the terms of a smart contract, or an update to a record. In this paper, we have developed a blockchain access control ecosystem that gives asset owners the sovereign right to effectively manage access control of large data sets and protect against data breaches. The Linux Foundation's Hyperledger Fabric blockchain is used to run the business network while the Hyperledger composer modeling tool is used to implement the smart contracts or transaction processing functions that run on the blockchain network.