To address the growing need for advanced tools that enable urban policymakers to conduct comprehensive cost-benefit analyses of traffic management changes, the Urbanite H2020 project has developed innovative artificial intelligence methods. Among them is a robust decision support system that assists policymakers in evaluating and selecting optimal urban mobility planning modifications by combining objective and subjective criteria. Utilising open-source microscopic traffic simulation tools, accurate digital models (or “digital twins”) of four pilot cities—Bilbao, Amsterdam, Helsinki, and Messina—were created, each addressing unique mobility challenges. These challenges include reducing private vehicle access in Bilbao’s city center, analysing the impact of increased bicycle traffic and population growth in Amsterdam, constructing a mobility-enhancing tunnel in Helsinki, and improving public transport connectivity in Messina. The research introduces five key innovations: the application of a consistent open-source simulation platform across diverse urban environments, addressing integration and consistency challenges; the pioneering use of Dexi for advanced decision support in smart cities; the implementation of advanced visualisations; and the integration of the machine learning tool, Orange, with a user-friendly GUI interface. These innovations collectively make complex data analysis accessible to non-technical users. By applying multi-label machine learning techniques, the decision-making process is accelerated by three orders of magnitude, significantly enhancing urban planning efficiency. The Urbanite project’s findings offer valuable insights into both anticipated and unexpected outcomes of mobility interventions, presenting a scalable, open-source AI-based framework for urban decision-makers worldwide.

As urban populations rise globally, cities face increasing challenges in managing urban mobility. This paper addresses the question of identifying which modifications to introduce regarding city mobility by evaluating potential solutions using city-specific, subjective multi-objective criteria. The innovative AI-based recommendation engine assists city planners and policymakers in prioritizing key urban mobility aspects for effective policy proposals. By leveraging multi-criteria decision analysis (MCDA) and ±1/2 analysis, this engine provides a structured approach to systematically and simultaneously navigate the complexities of urban mobility planning. The proposed approach aims to provide an open-source interoperable prototype for all smart cities to utilize such recommendation systems routinely, fostering efficient, sustainable, and forward-thinking urban mobility strategies. Case studies from four European cities—Helsinki (tunnel traffic), Amsterdam (bicycle traffic for a new city quarter), Messina (adding another bus line), and Bilbao (optimal timing for closing the city center)—highlight the engine’s transformative potential in shaping urban mobility policies. Ultimately, this contributes to more livable and resilient urban environments, based on advanced urban mobility management.

The objective of the URBANITE project is to design an open-data, open-source, smart-city framework to enhance the decision-making processes in European cities. The framework's basis is a robust and user-friendly simulation tool that is supplemented with several innovative service modules. One of the modules, a multi-output, machine-learning unit, is deployed on the simulation results, enabling city officials to more effectively analyse vast quantities of data, discern patterns and trends, and so facilitate advanced policy decisions. The city's decision makers define potential city scenarios, key performance indicators, and a utility function, while the module assists in identifying the policy that is best aligned with the stipulated constraints and preferences. One of the main improvements is a speeding up of the policy testing for the decision makers, reducing the time needed for one policy verification from 3 hours to around 10 seconds. The system was evaluated for Bilbao's Moyua area, where it suggested strategies that could result in a decrease in emissions of more than 5% $C{O}_2$, NOx, PM in the selected area and a broader part of the city with a machine-learning accuracy of 91%. The system was therefore able to provide valuable insights into effective policies for restricting private traffic in specific districts and identifying the most advantageous times for these restrictions.

Multimodal models have enabled the integration of digital pathology, radiology, clinical information, and omics data to enhance Colorectal cancer (CRC) care. This systematic review critically appraises Multimodal digital pathology techniques applied in CRC, their performance, and contrasts them with foundation models. We identified and screened 1601 studies published between January 2014 and August 2024 using PubMed, Web of Science, Scopus, and IEEE Xplore (PROSPERO protocol: 635831). The quality and bias of the 22 eligible studies were assessed using the Newcastle–Ottawa Scale. Our findings suggest that majority of the studies integrated different modalities to enhance diagnostic accuracy and survival prediction. Various fusion techniques have been used to extract novel features. Most studies did not undertake external validation. Compared to unimodal models, multimodal approaches demonstrate superior performance but challenges remain, including constructing multimodal datasets, managing data heterogeneity, ensuring temporal alignment, determining modality weighting, and improving interpretability.

The URBANITE H2020 project aims to address urban mobility challenges caused by growth and new transportation methods. It develops a decision support system for policymakers, incorporating simulation, evaluation of key performance indicators (KPIs), a recommendation/decision support system (DSS), and machine learning (ML) capabilities. The system helps identify and improve KPIs, proposes effective policies, and enhances urban digital transformation for sustainable and efficient mobility

This paper presents a novel multimodal fusion-based framework for colorectal cancer (CRC) survival prediction, integrating whole-slide images (WSIs) with clinical and biomarker data. The framework combines the ProvGigaPath model for WSI feature extraction and the TabTransformer for tabular data representation. Two fusion strategies were explored: contrastive learning (CL) on limited data and cross-attention (CA) for intermediate-level integration. Experiments on the Molecular and Cellular Oncology (MCO) dataset showed that CL achieves AUROCs of 0.82 (tabular) and 0.73 (image), while CA-based multimodal fusion attains a C-index of 0.77, surpassing unimodal baselines.