Alexandru-Cristian Filip

Dr. Alexandru-Cristian Filip

Central Military Emergency University Hospital ‘Dr. Carol Davila’, Bucharest, Bucureşti, Romania
orcid

Research Focus & Metrics

Academic Career Length

5Years (2022-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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2 May 2022 in Medicina
Verified
Journal Article
Open access
PDF file
AFAlexandru-Cristian Filip
Alexandru-Cristian Filip
CACuculici G Stefan Alexandru
Cuculici G Stefan Alexandru
SCStefan Cristea
Stefan Cristea
Viviana FilipViviana Filip
Viviana Filip
ANAlexis Negrea
Alexis Negrea
CPCosmin Marian Pantu
Cosmin Marian Pantu
Background and Objectives: This study’s purpose was to examine the benefit of using a tibial extension in the primary operation of total knee arthroplasty (TKA). This is important because it is not a common practice to use the extension in a primary TKA, a standard configuration offering sufficient stability and good long-term survivorship. The following question arises: which situation requires the use of a standard configuration implant (without a stem) and which situation requires using the extension? Materials and Methods: The opportunity to use the tibial extension in the primary TKA was analyzed in correlation to the tibial bone structural properties. Using finite elements (FEs), the virtual model of the tibial bone was connected to that of the prosthetic implant, with and without a stem, and its behavior was analyzed during static and dynamic stresses, both in the situation in which the bone had normal physical properties, as well as in the case in which the bone had diminished physical properties. Results: The maximum stress and displacement values in the static compression regime show that adding a stem is only beneficial to structurally altered bone. Compression fatigue was reduced to almost half in the case of altered bone when adding a stem. Dynamic compression showed slightly better results with the tibial stem in both healthy and degraded bone. Conclusions: It was concluded that, if the bone is healthy and has good structural properties, it is not necessary to use the tibial extension in the primary operation; and if the bone has diminished physical properties, it is necessary to use the tibial extension at the primary operation, enhancing the stability, fixation, and implant lifespan.

24 April 2022 in Medicina
Verified
Journal Article
Open access
PDF file
MPMaria Gabriela Puiu
Maria Gabriela Puiu
VDVlad Dionisie
Vlad Dionisie
AFAlexandru-Cristian Filip
Alexandru-Cristian Filip
MMMirela Manea
Mirela Manea
Porencephaly, a rare disease affecting the central nervous system, is represented by a cerebrospinal fluid-filled cavity in the brain. There are two types of porencephalic cavities: congenital and acquired. Porencephaly is mainly associated with neurological and developmental consequences. Associated psychotic symptoms were reported in a few cases, and due to this fact, there is a knowledge gap regarding the diagnostic and therapeutic approach to such cases. We present the case of a 32-year-old male diagnosed with a psychotic disorder associated with acquired porencephaly. The porencephalic cystic lesions were most probably due to a traumatic brain injury at the age of 6 years old. The psychotic symptomatology consisted of interoceptive/visceral hallucinations, delusions with persecutory and religious/magic content and disorganised behaviour. The porencephalic cavity was confirmed by a computed tomography scan. The patient was treated over the course of time with risperidone, olanzapine and zuclopenthixol. The existing literature regarding other cases of psychosis associated with porencephaly is discussed. In conclusion, even though porencephaly was asymptomatic for a long period of time, we argue that there is a causal relationship between the chronic psychotic symptoms and the porencephalic cyst in our case.

1 July 2024 in Romanian Journal of Military Medicine
Verified
Journal Article
Closed access
INIoana A. Negoiță
Ioana A. Negoiță
AFAlexandru-Cristian Filip
Alexandru-Cristian Filip
FNFlorin Năftănăilă-Mali
Florin Năftănăilă-Mali
ESElena D. Soloman-Năftănăilă-Mali
Elena D. Soloman-Năftănăilă-Mali
ICIoana M. Cobani
Ioana M. Cobani
ACAnca-Pati Cucu
Anca-Pati Cucu
This paper focuses on the role of diffusion-weighted MRI of ovarian tumors as a potential biomarker to detect and characterize malignancy, and to improve the accuracy of preoperative diagnosis and postoperative follow-up to optimize therapeutic management. This is an original retrospective study of 76 patients with ovarian masses who underwent surgery between May 2014 and March 2016 at the "Dr Carol Davila" Central Military University Gynaecology Department. Patients underwent preoperative, 6-month, and 12-month postoperative evaluation of ovarian tumors using diffusion-weighted MRI. Due to the accuracy of this method using specific sequences in tissue characterization, magnetic resonance imaging can be used in the diagnostic work-up of complex adnexal masses.