In recent decades, cementless implants have been widely used in clinical practice to replace missing organs, to replace damaged or missing bone tissue or to restore joint functionality. However, there remain risks of failure which may have dramatic consequences. The success of an implant depends on its stability, which is determined by the biomechanical properties of the bone–implant interface (BII). The aim of this review article is to provide more insight on the current state of the art concerning the evolution of the biomechanical properties of the BII as a function of the implant's environment. The main characteristics of the BII and the determinants of implant stability are first introduced. Then, the different mechanical methods that have been employed to derive the macroscopic properties of the BII will be described. The experimental multi-modality approaches used to determine the microscopic biomechanical properties of periprosthetic newly formed bone tissue are also reviewed. Eventually, the influence of the implant's properties, in terms of both surface properties and biomaterials, is investigated. A better understanding of the phenomena occurring at the BII will lead to (i) medical devices that help surgeons to determine an implant's stability and (ii) an improvement in the quality of implants.

This paper was accepted for publication in the journal Polymer Testing and the definitive published version is available at http://dx.doi.org/10.1016/j.polymertesting.2015.03.021Hydrogels are finding increasingly broad use, especially in biomedical applications. Their complex structure - a low-density network of microfibrils - defines their non-trivial mechanical behaviour. The focus of this work is on test-based quantification of mechanical behaviour of a bacterial cellulose (BC) hydrogel exposed to cyclic loading. Specimens for the tests were produced using Gluconacetobacter xylinus ATCC 53582 and tested in aqua under uniaxial cyclic loading conditions in a displacement-controlled regime. Substantial microstructural changes were observed in the process of deformation. A combination of qualitative microstructural observations with quantitative force-displacement relations allowed identification of main deformation mechanisms, confirming inelastic behaviour of the BC hydrogel under a loading-unloading-reloading regime. Elastic deformation was accompanied by non-elastic (viscoplastic) deformation in both tension and compression. This study also aims to establish a background for micromechanical modelling of overall properties of BC hydrogels

Dielectric elastomer actuators (DEAs) have attracted growing research interest over the past two decades for their large actuation strain, inherent compliance, and low cost. The conical DEA configuration is particularly attractive thanks to their simple structure and high force/stroke actuation. A double cone DEA design with two antagonistic membranes allows active bidirectional actuation. However, in existing double cone DEA designs, the two membranes are rigidly coupled, which restricts their relative actuation response under periodic electrical input to 180° out-of-phase operation. This work presents a magnetically coupled DEA with compliant coupling by a magnetic repulsion. The compliant coupling allows two separate inputs with a fully adjustable phase difference. The current prototype demonstrates a peak normalized stroke of 14% (relative to the nominal DEA height) at a phase shift of 180° and a normalized linear expansion between the two membranes of up to 8.3% (relative to the nominal DEA height) at a phase shift of 0° at 0.5 Hz. This results in several emerging actuation behaviors, which could potentially be suitable for controllable shape changing actuations, active vibration damping, and bioinspired locomotion.