Corneluta Fira-Mladinescu

Prof. Dr. Corneluta Fira-Mladinescu

orcid

Research Focus & Metrics

Academic Career Length

6Years (2021-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

View All Publications
RMRoxana Margan
Roxana Margan
Madalin-Marius MarganMadalin-Marius Margan
Madalin-Marius Margan
CFCorneluta Fira-Mladinescu
Corneluta Fira-Mladinescu
SPSalomeia Putnoky
Salomeia Putnoky
ITIoana Tuta-Sas
Ioana Tuta-Sas
ADAmadeus Dobrescu
Amadeus Dobrescu
Around 20% of couples worldwide are affected by infertility issues, with numbers in the European Union reaching as high as 25%, while access to reproductive care varies significantly by geopolitical and country-specific variables. The purpose of this research is to shed light on the unique social, psychological, and financial difficulties faced by Romanian couples seeking access to assisted reproductive therapy (ART). A cross-sectional study was conducted between 2017 and 2019 to involve women who accessed ART at fertility clinics in Romania by completing two infertility surveys. We analyzed the data in terms of all facets of infertility and ART, including the effect of personal background and stress levels on succeeding to conceive, the impact of treatment costs, and household income. A total of 829 participants completed the survey. We observed that high stress exposure leads to a substantially higher duration to conceive using ART, although the proportions of successful pregnancies did not differ between low-stress and high-stress groups. A significantly higher number of couples achieved pregnancy when their monthly household income was higher than EUR 1000 and if the ART method was more expensive. Additionally, we observed that advanced age, high stress levels, and the high cost of ART had a negative association with achieving pregnancy using ART. The findings indicated that Romanian couples experiencing infertility must contend with significant expenses for specialist infertility treatments, as well as treatment-related stress, both of which have a detrimental effect on their odds of attaining conception.

25 November 2024 in Antibiotics
Verified
Journal Article
Open access
PDF file
SLSorina Maria Denisa Laitin
Sorina Maria Denisa Laitin
LBLuminita Mirela Baditoiu
Luminita Mirela Baditoiu
RLRuxandra Laza
Ruxandra Laza
I(Irina Maria Stefan (Popescu)
Irina Maria Stefan (Popescu)
RBRăzvan-Sebastian Beșliu
Răzvan-Sebastian Beșliu
CFCorneluta Fira-Mladinescu
Corneluta Fira-Mladinescu
Background/Objectives: Antimicrobial resistance (AMR) is a critical global health threat, leading to increased morbidity, mortality, and healthcare costs. This study aimed to identify the most common bacterial pathogens and their resistance profiles from 2179 positive clinical cultures from inpatients at “Victor Babes” Hospital of Infectious Disease and Pneumoftiziology Timisoara in 2023. Methods: Samples were collected from sputum, bronchial aspiration, hemoculture, urine, wound secretions, catheter samples, and other clinical specimens. Results: Key pathogens identified included Klebsiella pneumoniae, Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa, and Acinetobacter baumannii, with notable resistance patterns, observed K. pneumoniae exhibited high resistance rates, notably 41.41% in Quarter 1, while E. coli showed 35.93% resistance in the same period. S. aureus, particularly MRSA, remained a persistent challenge, with 169 cases recorded over the year. A. baumannii and P. aeruginosa displayed alarming levels of multi-drug resistance, especially in Quarter 3 (88.24% and 22.02%, respectively). Although there was a general decline in resistance rates by Quarter 4, critical pathogens such as S. aureus and K. pneumoniae continued to exhibit significant resistance (81.25% and 21.74%, respectively). Conclusions: The study’s findings align with the broader antimicrobial resistance trends observed in Romania, where high resistance rates in K. pneumoniae, E. coli, S. aureus (MRSA), Acinetobacter, and Pseudomonas species have been widely reported, reflecting the country’s ongoing struggle with multi-drug-resistant infections. Despite some reductions in resistance rates across quarters, the persistent presence of these resistant strains underscores the critical need for strengthened antimicrobial stewardship, infection control measures, and continuous surveillance to combat the growing threat of AMR in Romania and similar healthcare settings.

24 January 2024 in Sustainability
Verified
Journal Article
Open access
PDF file
IMIoana MARIN
Ioana MARIN
CFCorneluta Fira-Mladinescu
Corneluta Fira-Mladinescu
Catalin Nicolae MarinCatalin Nicolae Marin
Catalin Nicolae Marin
VSVictoria Stan
Victoria Stan
SUSorin Ursoniu
Sorin Ursoniu
The assessment of the health status of healthcare workers (HWs) is related to the growing interest in the sustainability of the medical profession. This study explores for the first time the level of burnout, coping strategies, and pulse wave velocity (PWV), the correlations between them, and possible connections with the workplace. It included 154 HWs, aged 25–64 years, 83.76% women, divided into five groups (oncology, cardiology, intensive care, occupational health, and residents). The Burnout Assessment Tool (BAT-23) questionnaire for the burnout level and the Carver Coping Orientation to Problems Experienced (COPE) questionnaire for the coping strategies were used. PWV was measured with a TensioMed arteriograph. Regarding BAT subscales, all studied groups are at burnout for exhaustion (E), prone to burnout for mental distancing (MD), emotional impairment (EI), and no burnout for cognitive impairment (CI). On the four subscales of the BAT, the MANOVA shows a medium-sized effect of the workplace on MD and on CI. All subjects use positive coping strategies. Problem-solving mechanisms are often used, followed by emotional support-based and social support-based coping. PWV correlates with age and BMI and has a small positive correlation with MD, CI, and EI. High burnout levels are related to the healthcare profession, not to the workplace. Our research shows the practical need to supervise the mental and physical health of HWs in order to preserve their health through medical and organizational methods.

4 November 2024 in Journal of Clinical Medicine
Verified
Journal Article
Open access
PDF file
ATAna Adriana Trușculescu
Ana Adriana Trușculescu
Versavia Maria AncusaVersavia Maria Ancusa
Versavia Maria Ancusa
CPCamelia Corina Pescaru
Camelia Corina Pescaru
Norbert WellmannNorbert Wellmann
Norbert Wellmann
CFCorneluta Fira-Mladinescu
Corneluta Fira-Mladinescu
Ovidiu Fira-MladinescuOvidiu Fira-Mladinescu
Ovidiu Fira-Mladinescu
Background: Status asthmaticus is a severe, life-threatening asthma exacerbation requiring urgent medical intervention. This study aims to examine its epidemiology in Timis County, Romania, over 11 years. Methods: A retrospective analysis was conducted using hospital records from 2013 to 2023, focusing on demographic, geospatial, and temporal distributions. Network analysis of the recorded comorbidities was used to identify phenotypic clusters among patients. Results: Females and older adults were disproportionately affected. Several triggers and geospatial patterns were identified. Five phenotypic clusters were determined: two in the T2-high endotype, two in T2-low, and a mixed one. Conclusions: The findings highlight the need for personalized asthma management strategies and public healthcare interventions in Timiș County, addressing specific demographic and geospatial factors. This study also provides a valuable reference for similar regions.

1 May 2021 in Psychology Research and Behavior Management
Verified
Journal Article
Open access
PDF file
Miloicov Bacean Oana CodrutaMiloicov Bacean Oana Codruta
Miloicov Bacean Oana Codruta
Ovidiu Fira-MladinescuOvidiu Fira-Mladinescu
Ovidiu Fira-Mladinescu
SPSalomeia Putnoky
Salomeia Putnoky
ITIoana Tuta-Sas
Ioana Tuta-Sas
PCPetrescu Cristina
Petrescu Cristina
BVBrigitha Vlaicu
Brigitha Vlaicu
Purpose: The aims of this study were to evaluate high school pupils’ relationships with their parents, schoolmates, and friends, and the presence of health-related risk behaviors among the family members and friends on the pupils’ smoking and binge drinking status. Materials and Methods: The study was a cross-sectional population-based study that involved a questionnaire, and the sample involved 2908 pupils at high schools in Timis county, Romania. In our study, the following factors related to family members and friends and the living environment were identified. First, there were issues with the relationships with parents among some pupils, with 23.2% being neither satisfied nor unsatisfied and 4.9% being unsatisfied. Second, there were also issues regarding some pupils’ satisfaction with the financial situation of their family, with 21.8% being neither satisfied nor unsatisfied and 16.4% being unsatisfied. An odds ratio (OR) is a statistic that quantifies the strength of the association between two events. Results: There were 1495 (51.5%) girls and 1407 (48.5%) boys aged 14– 20 years, and 79.2% came from organized families. Among the pupils, 71.1% reported that they were satisfied with their relationship with their parents, while 4.9% were unsatisfied. Additionally, 46.2% were satisfied with the financial status of their families, while 16.4% were unsatisfied. Moreover, 59.2% were satisfied with their relationship with their schoolmates and 80.2% were satisfied with their relationship with their friends, while only 1.8% were unsatisfied with their relationship with their friends. The logistic regression model of the pupils’ smoking status identified two moderate predictive factors: this was defined “> 1” friends who smoke (odds ratio [OR]=2.875) and smoking status of siblings (OR=2.222). The major predictive factor in the logistic regression model of occasional alcohol consumption in high quantities by pupils was male gender (OR=5.148). Conclusion: The predictive model of pupils’ smoking status identified the following moderate predictors: high number of friends who smoke and smoking status of siblings. The major predictor in the model of occasional alcohol consumption in high quantities by pupils was male gender.

26 May 2022 in Medicina
Verified
Journal Article
Open access
PDF file
IMIoana MARIN
Ioana MARIN
MIMircea Stefan Iurciuc
Mircea Stefan Iurciuc
FPFlorina Georgeta Popescu
Florina Georgeta Popescu
SIStela Iurciuc
Stela Iurciuc
CPCalin Marius Popoiu
Calin Marius Popoiu
CFCorneluta Fira-Mladinescu
Corneluta Fira-Mladinescu
Background and Objectives: In the COVID-19 epidemiological context, the health care workers who were treating patients with COVID-19 were exposed daily to additional stress. Pulse wave velocity (PWV) is a predictive parameter for possible major adverse cardiovascular events. The present study aimed to evaluate the correlation between the general stress levels and PWVs of medical workers during the COVID-19 pandemic. Materials and Methods: The study group was heterogeneous in terms of the medical profession. PWV was measured using a TendioMed arteriograph. Assessment of stress level was performed using a general stress questionnaire with questions grouped on the areas that contribute to stress: lifestyle, environment, symptoms, job, relationships and personality. PWV measurements and stress assessment were performed both during the period with many patients with COVID-19 and during the period with few patients with COVID-19. Results: The stress levels and PWVs of subjects were higher in the period when they cared for patients with COVID-19 than in the period when they did not have patients with COVID-19. Conclusions: The study shows a positive correlation between the PWV of each subject and his/her stress score (the higher the stress score, the higher the PWV).