The transport sector is responsible for several environmental impacts, including contributions to climate change through greenhouse gas emissions and depleting natural resources. A strategy to reduce these issues goes towards the application of a circular economy, a concept that offers a response to increasing concerns about resource scarcity and the associated impacts from their use. Thus, this paper aims to fill a gap in the literature that consists of the scarcity of studies that consider the circular economy application on a micro, meso, and macro level in road transport, including all stages as well as the 7 Rs of the reverse cycle. Therefore, an approach is presented to meet road transport needs, highlighting best practices obtained through a literature review, to promote climate change mitigation and resource depletion. Qualitative data were presented for each circular economy stage with 46 best practices identified, providing invaluable guidance to transport decision-makers. Thus, public policies focusing on all of the CE stages should be taken into consideration, not only those responsible for closing the cycle, such as waste and recycling or disposal and treatment.