A mathematical model was developed to describe the processes of coupled heat and mass and momentum transfer occurring in convective drying of 100% porous cotton fabric. In this model, the variation in both air and fabric properties were expressed as a function of temperature and moisture content. The resulting systems of transient non-linear partial differential equations in the space-time domain together with the set of initial values and boundary conditions were numerically solved by utilizing the finite difference method. A series of laboratory drying experiments were performed using a computer-controlled dehydration system, which was developed to obtain data of drying kinetics under varying operating conditions for the validation of the predicted results from the proposed model. The experimental results has shown a very good agreement with the predictions of the model, which indicates that the proposed numerical model can be used with confidence as a tool in optimizing the design and operation of the fabric drying system. A parametric study was performed using the modeling tool has demonstrated the impact of key operational parameters on the drying kinetics, which has significant meaning on improving fabric’s appearance smoothness and decreasing the damage. It is expected that the model can be applied for other fiber products and processes involving similar phenomena.

This study aimed to examine the effect of fabric movement on drying efficiency of the domestic drum dryer under various conditions including the type of textile material, drying load, fabric size and rotating speed of drum. A high-speed camera was utilized to monitor the outlines of the fabric in the drying process. The results indicated that the fabric movement patterns shifted from sliding or falling to rotating with the decrease of drying load and the fabric size or the increase of the rotating speed of drum. Additionally, the complex movement patterns involving successively sliding, falling, swing and rotating in the drying process presented higher drying efficiency than the repeated single movement patterns such as sliding or rotating. The optimum rotating speed range of 45–50 rpm in complex movement patterns afforded the highest drying efficiency and improved the appearance smoothness of fabric after drying.

The aim of this study was to investigate the pharmacokinetics of glibenclamide (Gli) administrated orally and intravenously to normal and diabetic rats. The AUC(0–720min) of orally administered Gli in diabetic rats (321.24mgmin/L) was greater than that (57.752mgmin/L) in normal rats. CL (0.019L/min/kg) was significantly slower than that (0.092L/min/kg) of normal rats. The AUC(0–480min) of intravenous Gli in diabetic rats (1528.280mgmin/L) also was significantly greater than that (509.523mgmin/L) in normal rats, and CL was decreased approximately 3-fold. No significant difference in intestinal absorption of Gli was observed between normal and diabetic rats as determined by in situ single-pass intestinal perfusion. The clearance of Diclofenac (a substrate of CYP2C9) was determined to evaluate changes in hepatic drug-metabolizing enzyme activity in rats. The CL in diabetic rats was significantly lower (42.43% decrease) than that in normal rats. Hepatic protein expression of CYP2C9 was measured using Western blot analysis; compared with normal rats, the hepatic protein expression of CYP2A9 was decreased in diabetic rats. Therefore, the slower clearance of Gli in diabetic rats can be attributed primarily to the lower expression of hepatic CYP2C9