Tuberculosis (TB) is still a major public health concern, despite the availability of preventative and curative therapies. Significant progress has been made in the past decade towards its control. However, the emergence of the novel coronavirus disease 2019 (COVID-19) has disrupted numerous essential health services, including those for TB. This scoping review maps the available evidence on TB services at the primary healthcare (PHC) level during the COVID-19 period. A comprehensive literature search was conducted in PubMed, Web of Science, Medline OVID, Medline EBSCO, and Scopus. A total of 820 articles were retrieved from the databases and 21 met the eligibility criteria and were used for data extraction. The emerging themes were the effect of the COVID-19 pandemic on TB services, patient and provider experiences, recommendations for TB services during the COVID-19 period, and the implementation of the recommendations. The review found that the mitigation strategies, as well as fear and stigma experienced at the start of the COVID-19 pandemic may have led to TB cases potentially going undetected, which may threaten TB treatment outcomes. Therefore, efforts must be directed at finding these missing cases and ensuring that PHC facilities are equipped to adequately diagnose and treat them.

Background: Sexually transmitted infections (STIs) are a major global healthcare burden, disproportionately affecting women. Self-sampling interventions for diagnostic purposes have the potential to improve STI healthcare management and expand STI services. However, there is currently no published evidence of the global use of self-sampling interventions to diagnose STIs in women. The main aim of this scoping review was to map evidence on the use of self-sampling interventions to diagnose STIs in women. Methodology: The methodology of this scoping review was guided by Arksey and O’Malley and Levac. A comprehensive literature search was conducted in PubMed, Scopus, Web of Science, Medline (EBSCO), ProQuest, and Cochrane. For grey literature, a search was conducted in Open Grey, World Health Organization, Google, and conference proceedings and dissertations. All search results were screened and assessed for eligibility. Thereafter data from eligible studies was extracted and analysed. The quality of these studies was appraised using the Mixed Methods Appraisal Tool 2018 version. Results: A total of 770 articles were retrieved from databases and grey literature sources. A total of 44 studies were eligible for data extraction following title, abstract and full-text screening. Of the included studies, 63% presented evidence of research conducted in high-income countries and 37% presented evidence in low- and middle-income countries. Studies presented evidence on the following: feasibility of self-sampling in remote areas; acceptance and ease of use of self-sampling interventions; types of self-sampled specimens; pooled samples for diagnosing STIs; laboratory diagnostic assays for STI using self-sampled specimens; and self-testing of self-sampled specimens. Conclusions: Self-sampling interventions are feasible and easy to use and, therefore, can improve STI management and treatment in women across various age groups and various access levels to good-quality healthcare. Despite this, there is a lack of evidence of self-sampling interventions designed according to user preferences. We recommend studies to collaborate with women to co-develop user-friendly self-sampling interventions to diagnose STIs in women.

Background: Syndromic management in the main non-laboratory-based management approach for sexually transmitted infections (STI) in most low- and middle-income countries (LMICs) but it has limitations. Self-sampling has been proven as a suitable alternative approach to help improve management STIs by improving access to diagnosis among vulnerable populations. We sought to determine health workers’ perspectives on user-friendly self-sampling interventions for STIs among young women in eThekwini District Municipality. Methods: Healthcare workers providing STI healthcare services in the study location participated in a nominal group technique (NGT) workshop. The NGT workshop was aimed enabling collaboration with key health providers in identifying user-friendly self-sampling interventions for diagnosis of STIs among young women. Data collection was conducted in two phases: phase 1 determined barrier that hinder young women from accessing current STI healthcare services and phase 2 focused on determining the key strategies for self-sampling interventions to diagnose STIs in young women. Thematic analysis and percentage form analysis were used to examine qualitative and quantitative data respectively. Results: The following barriers were identified: negligence; myths about STIs; fear of judgement; denial; operating hours; lack of knowledge of STI symptoms and safe sex practices; and stigma associated with STIs. The following strategies were suggested: hand out self-sampling kits at popular restaurants; collect self-sampling kits from security guard at primary healthcare clinics (PHCs); receive STI diagnostic results via SMS or email or the clinic for treatment; improve youth friendly services at PHCs; educate the public on proper use of the kits. Education about STIs and handing out self-sampling kits at clinics, universities, schools, pharmacies or via outreach teams were ranked high priority strategies. Conclusions: The findings highlight the need to address stigma and fear of judgment and provide comprehensive education to improve healthcare-seeking behaviour in young women. Additionally, the study also indicates that using eHealth solutions could significantly enhance the accessibility and efficiency of STI healthcare services in LMICs.

Introduction Sexually transmitted infections (STIs) are a significant public health concern globally, particularly affecting young women. Early diagnosis and treatment are essential to reducing or stopping the continuous spread of infections and the development of associated complications. Syndromic management, which is commonly used for STIs, presents several barriers, particularly for young women. This protocol is for a study that aims to understand young women’s preferences for a self-sampling intervention for STI diagnosis by using a discrete choice experiment (DCE). The DCE will be conducted among young women residing in underserved urban communities in eThekwini Metropolitan Municipality in KwaZulu-Natal, South Africa. Methods and analysis The following attributes of a self-sampling intervention were identified through a Nominal Group Technique: accessibility, education, confidentiality, self-sampling method, youth-friendliness and cost. A pilot study involving 20 participants was conducted to refine the DCE questionnaire. A total of 196 young women from underserved communities will be recruited. The participants will be sampled from communities, stratified by settlement type and socioeconomic status. Data will be analysed using the multinomial logit model and mixed logit model to assess preferences and heterogeneity. Ethics and dissemination The study was approved by the Faculty of Health Sciences Research Ethics Committee of the University of Pretoria. The study findings have the potential to inform policies for STI treatment and management to align healthcare services with user preferences. This can improve STI healthcare access for young women in underserved communities. Ethical approval was obtained, and results will be disseminated through peer-reviewed journals and health conferences.

Background: Cervical cancer is one of the leading causes of cancer-related death in women. The role of religious beliefs in shaping beliefs and practices in people has been proven. This research examines the views and perceptions of women in religious settings, with a specific focus on women from the Nazareth Church in Umlazi, in KwaZulu-Natal, in South Africa, regarding cervical cancer. The study aims to explore the role of religious groups in cervical cancer prevention and control. Methods: A qualitative survey questionnaire was used to collect data from a randomly selected sample of women from a Nazareth church in Umlazi, aged 18 years and above. The themes covered in the questionnaire included knowledge and awareness of cervical cancer, understanding of the disease, causes and risk factors, signs, and symptoms, curability, disease complications, participants' knowledge sources, awareness of screening, and screening history. Results: Findings revealed a significant knowledge gap among the surveyed women, with a substantial proportion reporting limited awareness of cervical cancer. Understanding of the disease, its causes, and risk factors was found to be incomplete, highlighting the need for targeted educational interventions. Screening rates were low, indicating the importance of promoting cervical cancer screening and addressing barriers to screening uptake. Conclusion: Overall, the findings highlight the need for comprehensive educational campaigns, improved access to screening services, and targeted interventions to enhance knowledge, awareness, and uptake of cervical cancer prevention and screening measures among women. They also highlight the need for healthcare providers to collaborate with religious groups to develop targeted interventions and educational programs that align with religious beliefs and practices. Such efforts have the potential to enhance knowledge, awareness, and screening rates, and ultimately impact the burden of cervical cancer among women in South Africa, and potentially across the globe.

Background: Cervical cancer is the second most common cause of cancer-related deaths among women globally, predominantly affecting women in low- and middle-income countries, including South Africa. Despite being preventable through early screening and human papillomavirus (HPV) vaccination, cervical cancer awareness and screening rates remain low. Female university students often exhibit limited knowledge and face unique barriers that impede cervical cancer screening uptake. The purpose of this study was to evaluate the level of knowledge and explore the barriers to cervical cancer screening among female students at a University of Technology in Durban, KwaZulu-Natal, South Africa. Methods: The research was conducted among female students across various faculties and academic levels at a University of Technology in Durban, KwaZulu Natal, South Africa. A quantitative, cross-sectional survey was conducted using a structured online questionnaire that examined student demographic profiles, knowledge of cervical cancer and HPV infection, and barriers to cervical cancer screening. A total of 131 female students were recruited, and data were analysed to identify knowledge gaps and barriers to screening uptake. Results: The study found a high level of awareness of cervical cancer (90.1%) and HPV (71.8%), though significant knowledge gaps in specific risk factors and screening methods persisted. The primary barriers identified included fear of test results, lack of awareness, and logistical challenges, such as time and financial constraints. Discomfort with discussing screening results also varied, with discomfort more pronounced among younger and lower-year students. Conclusion: Despite general awareness, significant barriers, including fear, insufficient knowledge, and logistical obstacles, limit cervical cancer screening uptake among female university students. This suggests that tailored interventions addressing knowledge gaps and providing practical support could improve screening rates and early detection, ultimately contributing to better health outcomes for young women in similar settings.