The coronavirus disease outbreak of 2019 (COVID-19) has been spreading rapidly to all corners of the word, in a very complex manner. A key research focus is in predicting the development trend of COVID-19 scientifically through mathematical modelling. We conducted a systematic review of epidemic prediction models of COVID-19 and the public health intervention strategies by searching the Web of Science database. 55 studies of the COVID-19 epidemic model were reviewed systematically. It was found that the COVID-19 epidemic models were different in the model type, acquisition method, hypothesis and distribution of key input parameters. Most studies used the gamma distribution to describe the key time period of COVID-19 infection, and some studies used the lognormal distribution, the Erlang distribution, and the Weibull distribution. The setting ranges of the incubation period, serial interval, infectious period and generation time were 4.9–7 days, 4.41–8.4 days, 2.3–10 days and 4.4–7.5 days, respectively, and more than half of the incubation periods were set to 5.1 or 5.2 days. Most models assumed that the latent period was consistent with the incubation period. Some models assumed that asymptomatic infections were infectious or pre-symptomatic transmission was possible, which overestimated the value of R0. For the prediction differences under different public health strategies, the most significant effect was in travel restrictions. There were different studies on the impact of contact tracking and social isolation, but it was considered that improving the quarantine rate and reporting rate, and the use of protective face mask were essential for epidemic prevention and control. The input epidemiological parameters of the prediction models had significant differences in the prediction of the severity of the epidemic spread. Therefore, prevention and control institutions should be cautious when formulating public health strategies by based on the prediction results of mathematical models.
The severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) is highly contagious, and the coronavirus disease 2019 (COVID-19) pandemic caused by it has forced many countries to adopt ‘lockdown’ measures to prevent the spread of the epidemic through social isolation of citizens. Some countries proposed universal mask wearing as a protection measure of public health to strengthen national prevention efforts and to limit the wider spread of the epidemic. In order to reveal the epidemic prevention efficacy of masks, this paper systematically evaluates the experimental studies of various masks and filter materials, summarises the general characteristics of the filtration efficiency of isolation masks with particle size, and reveals the actual efficacy of masks by combining the volume distribution characteristics of human exhaled droplets with different particle sizes and the SARS-CoV-2 virus load of nasopharynx and throat swabs from patients. The existing measured data show that the filtration efficiency of all kinds of masks for large particles and extra-large droplets is close to 100%. From the perspective of filtering the total number of pathogens discharged in the environment and protecting vulnerable individuals from breathing live viruses, the mask has a higher protective effect. If considering the weighted average filtration efficiency with different particle sizes, the filtration efficiencies of the N95 mask and the ordinary mask are 99.4% and 98.5%, respectively. The mask can avoid releasing active viruses to the environment from the source of infection, thus maximising the protection of vulnerable individuals by reducing the probability of inhaling a virus. Therefore, if the whole society strictly implements the policy of publicly wearing masks, the risk of large-scale spread of the epidemic can be greatly reduced. Compared with the overall cost of social isolation, limited personal freedoms and forced suspension of economic activities, the inconvenience for citizens caused by wearing masks is perfectly acceptable.