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Cornelis Sier

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Cornelis F.M. Sier is a molecular biologist especially focused on cell–cell interactions in cancer. He studied biology at the Free University of Amsterdam (The Netherlands) and obtained his Ph.D. in 1993 at the Leiden University Medical Centre (Department of Gastroenterology and Hepatology) and TNO-Gaubius Institute in Leiden, The Netherlands. After a postdoc in the same department, he moved to the Università Vita Saluta San Raffaele in Milan (Italy), where he stayed for 5 years. In his period in Italy, he visited several institutes, including the Mario Negri Institute for Pharmacological Research (Milan, Italy) and the Finsen Laboratory, a basic cancer research department in Copenhagen (Denmark). He returned to the Leiden University Medical Centre performing research projects in the departments of Pathology, Gastroenterology, and Trauma Surgery. In the summer of 2010, he joined the CTMM consortium MUSIS, and became an associated member of the Image-Guided Oncologic Surgery group of the Leiden University Medical Center. In 2019, he joined Percuros BV, Leiden, The Netherlands, a small–medium sized high-tech enterprise focusing on medical research and development. His main focus is the evaluation of tumor markers as targets for image-guided surgery and diagnosis and the subsequent development of targeted probes against selected candidates.

Research Keywords & Expertise

Cancer
Imaging Technologies
Oncology Clinical Rese...
Target Identification
proteinases and inhibi...

Fingerprints

64%
Cancer
64%
cancer as
11%
tumor microenvironment
5%
cancer associated fibroblasts (CAFs)

Short Biography

Cornelis F.M. Sier is a molecular biologist especially focused on cell–cell interactions in cancer. He studied biology at the Free University of Amsterdam (The Netherlands) and obtained his Ph.D. in 1993 at the Leiden University Medical Centre (Department of Gastroenterology and Hepatology) and TNO-Gaubius Institute in Leiden, The Netherlands. After a postdoc in the same department, he moved to the Università Vita Saluta San Raffaele in Milan (Italy), where he stayed for 5 years. In his period in Italy, he visited several institutes, including the Mario Negri Institute for Pharmacological Research (Milan, Italy) and the Finsen Laboratory, a basic cancer research department in Copenhagen (Denmark). He returned to the Leiden University Medical Centre performing research projects in the departments of Pathology, Gastroenterology, and Trauma Surgery. In the summer of 2010, he joined the CTMM consortium MUSIS, and became an associated member of the Image-Guided Oncologic Surgery group of the Leiden University Medical Center. In 2019, he joined Percuros BV, Leiden, The Netherlands, a small–medium sized high-tech enterprise focusing on medical research and development. His main focus is the evaluation of tumor markers as targets for image-guided surgery and diagnosis and the subsequent development of targeted probes against selected candidates.