Zied Chaari

Prof. Zied Chaari

University of Sfax, Sfax, Tunisia
orcid

Research Focus & Metrics

Academic Career Length

14Years (2013-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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25 May 2022 in Cancers
Verified
Journal Article
Open access
PDF file
François MontagneFrançois Montagne
François Montagne
ZCZied Chaari
Zied Chaari
Benjamin BottetBenjamin Bottet
Benjamin Bottet
MSMatthieu Sarsam
Matthieu Sarsam
FMFrankie Mbadinga
Frankie Mbadinga
Jean-Marc BASTEJean-Marc BASTE
Jean-Marc BASTE
Background: Nowadays, video-assisted thoracoscopic surgery (VATS) and robotic-assisted thoracoscopic surgery (RATS) are known to be safe and efficient surgical procedures to treat early-stage non-small cell lung cancer (NSCLC). We assessed whether RATS increased disease-free survival (DFS) compared with VATS for lobectomy and segmentectomy. Methods: This retrospective cohort study included patients treated for resectable NSCLC performed by RATS or VATS, in our tertiary care center from 2012 to 2019. Patients’ data were prospectively recorded and reviewed in the French EPITHOR database. Primary outcomes were 5-year DFS for lobectomy and 3-year DFS for segmentectomy, compared by propensity-score adjusted difference of Kaplan–Meier estimates. Results: Among 844 lung resections, 436 VATS and 234 RATS lobectomies and 46 VATS and 128 RATS segmentectomies were performed. For lobectomy, the adjusted 5-year DFS was 60.9% (95% confidence interval (CI) 52.9–68.8%) for VATS and 52.7% (95%CI 41.7–63.7%) for RATS, with a difference estimated at −8.3% (−22.2–+4.9%, p = 0.24). For segmentectomy, the adjusted 3-year DFS was 84.6% (95%CI 69.8–99.0%) for VATS and 72.9% (95%CI 50.6–92.4%) for RATS, with a difference estimated at −11.7% (−38.7–+7.8%, p = 0.21). Conclusions: RATS failed to show its superiority over VATS for resectable NSCLC.

18 November 2021 in The Annals of Thoracic Surgery
Verified
Journal Article
Closed access
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ZCZied Chaari
Zied Chaari
AAAymen Ben Ayed
Aymen Ben Ayed
JTJihen Jdidi Trabelsi
Jihen Jdidi Trabelsi
WAWalid Abid
Walid Abid
JDJamel Dammak
Jamel Dammak
IFImed Frikha
Imed Frikha

23 October 2021 in Interactive CardioVascular and Thoracic Surgery
Verified
Journal Article
Open access
PDF file
ZCZied Chaari
Zied Chaari
François MontagneFrançois Montagne
François Montagne
MSMatthieu Sarsam
Matthieu Sarsam
Benjamin BottetBenjamin Bottet
Benjamin Bottet
PRPhilippe Rinieri
Philippe Rinieri
Jean-Marc BASTEJean-Marc BASTE
Jean-Marc BASTE
Our goal was to report our midterm results using imaging-assisted modalities with robotic segmentectomies for non-small-cell lung cancer (NSCLC). This was a retrospective study of all robotic segmentectomies, with confirmed NSCLC, performed at our general and thoracic surgery unit in the Rouen University Hospital (France), from January 2012 through December 2019. Benign and metastatic lesions were excluded. Data were extracted from the EPITHOR French nationwide database. A total of 121 robotic segmentectomies were performed for 118 patients with a median age of 65 (interquartile range: 60, 69) years. The majority had clinical stage T1aN0M0 (71.9%) or T1bN0M0 (13.2%). The mean (standard deviation) number of resected segments was 1.93 (1.09) with 80.2% imaging-assisted segmentectomies. Oriented (according to tumour location) or systematic lymphadenectomy or sampling was performed for 72.7%, 23.1% and 4.1% of patients. The postoperative course was uneventful for 94 patients (77.7%), whereas 34 complications occurred for 27 patients (22.3%), including 2 patients (1.7%) with Clavien-Dindo ≥III complications. The mean thoracic drainage duration was 4.12 days, and the median hospital stay was 4 days (interquartile range: 3, 5) after the operation. The 2-year survival rate was 93.9% (95% confidence interval: 86.4–97.8%). Excluding stage IV (n = 3) and stage 0 tumours (n = 6), the 2-year survival rate was 95.7% (95% confidence interval: 88.4–98.8%) compared to an expected survival rate of 94.0% according to stage-specific survival rates found in a large external reference cohort. Imaging-guided robotic-assisted thoracic surgery segmentectomy seems to be useful and oncological with good midterm results, especially for patients with early-stage NSCLC.

1 November 2018 in The Annals of Thoracic Surgery
Verified
Journal Article
Closed access
ZCZied Chaari
Zied Chaari
ADAymen Damak
Aymen Damak
NKNizar Kardoun
Nizar Kardoun
SHSaif Hadhri
Saif Hadhri
RHRaghda Hbaieb
Raghda Hbaieb
IFImed Frikha
Imed Frikha

14 December 2021 in Asian Cardiovascular and Thoracic Annals
Verified
Journal Article
Closed access
PDF file
ZCZied Chaari
Zied Chaari
AHAbdessalem Hentati
Abdessalem Hentati
AAAimen Ben Ayed
Aimen Ben Ayed
WAWalid Abid
Walid Abid
IFImed Frikha
Imed Frikha
Pulmonary surgery is often associated with postoperative prolonged parenchymal air-leak. The purpose of this study was to determine efficacy and safety of povidone iodine as treatment of prolonged parenchymal air-leak following all-types of lung surgery. This prospective trial was conducted from June 2019 to December 2020, and designed under PanAfrican Clinical Trials Registry requirements. Patients having prolonged parenchymal air-leak were randomly allocated to povidone iodine protocol (Group A) or surveillance without povidone iodine (Group B). We collected the number of povidone iodine injections required before bubbling stopped, total drainage period, tolerance after injection, complications and side-effects. Comparative study was performed to evaluate povidone iodine efficacy. Following randomization, Group A included 19 patients, and Group B 21. Both groups were comparable. The mean drainage period was 9.21 days in Group A (6–14 days) and 15.62 days in Group B (7–31 days) (p = 0.001). The mean hospitalization period was 11.05 days in Group A (7–16 days) and 18.9 days in Group B (9–38 days) (p < 0.0001). The mean follow-up period was 6.8 months (3–18 months). No deaths were noted in either groups. Four side-effects were reported in Group A (21%) and four serious complications were noticed in Group B (19%). No recurrences were reported in Group A versus one recurrence of homolateral pneumothorax in Group B (4.76%). Povidone iodine is an effective and safe solution for pleurodesis. It is associated with a low complication rate that remains acceptable, and could be proposed as treatment of prolonged parenchymal air-leak after lung resections.

27 August 2016 in Archives of Clinical Infectious Diseases
Verified
Journal Article
Open access
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MBMohamed-Sadok Boudaya
Mohamed-Sadok Boudaya
MMMona Mlika
Mona Mlika
ZCZied Chaari
Zied Chaari
HZHazem Zribi
Hazem Zribi
SASamira Aouadi
Samira Aouadi
TKTarek Kilani
Tarek Kilani
Background: Hydatidosis is an infectious disease resulting from the development of the larval form of the parasite Echinococcus granulosus in humans. The invasion of the chest wall by echinococcosis is rarely described. Methods: The current study reported all cases of chest wall hydatidosis treated in the department of cardiothoracic surgery from January 1990 to December 2011. Results: The mean age of the patients was 41.3 ± 16.8 years. Males and females were equally affected. The cysts mostly were located at ribs (13 cases) and ribs with vertebrae (10 cases). The chest wall muscles, the sub-cutaneous tissue and the sternum were involved in four, three and two cases, respectively. A costal resection was performed in 13 cases (one to three ribs; mean, 1.5 ribs) and a costovertebral resection was performed in 10 cases (transverse process three, vertebral body four and both three). The other surgical procedures were partial resection of the sternum (two cases) and cystectomy with resection of parietal soft tissue (nine cases). The outcome was favorable for 29 patients. A recurrence was observed in two patients who presented costovertebral and sternal involvements. Conclusions: The chest wall localization of the hydatid cyst is rare. In the costovertebral involvements, this parasitic disease behaves locally as a bone malignancy. The treatment is surgical and the resection should be large and radical to avoid recurrences. Keywords: Chest Wall; Hydatid Cyst; Echinococcosis