Diarrhoeal disease is the second leading cause of death among children aged below 5 years. Even though, both preventable and treatable diseases, globally there are nearly 1.7 billion cases of childhood diarrhoeal disease and responsible for killing around 525,000 children every year. Shigella and Salmonella species were the leading cause of etiologic agents for diarrhoea associated deaths. The aim of this study was to determine the prevalence and antibiotic susceptibility patterns of Shigella and Salmonella isolated from children aged below 5 years with diarrhoea attending Nigist Eleni Mohammed Memorial Hospital, Hossana, South Ethiopia. A cross sectional study was conducted from June 02 to September 24, 2017. Two hundred four children aged below 5 years with diarrhoea were enrolled consecutively using convenience sampling technique. Stool specimens were processed in accordance with the standard bacteriological methods and antibiotic susceptibility pattern of the isolates was determined using disc diffusion method. Data were analyzed using SPSS version 20. Out of the 204 children aged below 5 years with diarrhoeal disease 19/204 (9.3%, [95%CI, 5.7–13.7%]) of them were positive for bacterial growth, of which 17/204(8.3%) were Shigella species and 2/204(1%) were Salmonella species. Both Shigella and Salmonella isolates were 100% susceptible to norfloxacin, nalidixic acid and kanamycin. However, isolates of Shigella showed 100, 76.5 and 64.7% resistance to ampicillin, gentamicin and cotrimoxazole respectively while Salmonella species were highly resistant to ampicillin and gentamicin (100% each). Salmonella and Shigella species is prevalent in the current study area. Among the tested antibiotics, norfloxacin, nalidixic acid and kanamycin were found to be most effective for both isolates. Both species are developing resistance to the commonly prescribed antibiotic. Therefore, culture based bacterial species identification and antimicrobial susceptibility testing services are strongly recommended to avoid empirical treatment in the study area.
Background: Hypertension is a leading cause of cardio-vascular diseases and its attributed mortality. No previous study, however, assessed the prevalence and associated factors of hypertension in the study area.Methods: We recruited a representative sample of 627 adult individuals from selected kebeles of Hosanna town. A multi-stage sampling technique was employed in the study. A structured questionnaire using the WHO STEPS approach was employed to conduct a face to face interview and physical measurements. For each participant, we measured blood pressure two times after giving 10 minutes breaks between the measurements and we took the average. Hypertension status was defined as “systolic blood pressure ≥140mmhg and/or diastolic blood pressure ≥90mmhg”. Undiagnosed hypertension was defined as participants who had raised blood pressure on measurement, but not aware of it before. We used Multivariable logistic regression model to determine factors associated with hypertension.Results: The overall prevalence of hypertension was found to be 17.2% (95% CI 14.5 – 19.9), 19.3% among men and 14.2% among women, of which 10.2% were unaware of it before. Hypertension was significantly associated with old age ≥35 years, excess alcohol intake, consumption of saturated oil/fat), consumption of unspecified different types of oil/fat and overweight/obesity.Conclusion: The prevalence of hypertension (both diagnosed and undiagnosed) in the town is unacceptably high. This is also related to modifiable risk factors like excessive alcohol intake, overweight/obesity and consumption of saturated fat/oil. Therefore, designing health information provision systems on the risk factors of hypertension and promotion of good health practices should be considered. Moreover, the health departments should facilitate blood pressure screening programs at community levels to identify and treat undiagnosed hypertension.