Grzegorz Maria Popowicz studied physics and biochemistry under the supervision of Professor Rober Huber (Nobel Prize in Chemistry, 1988). His research activity evolved from structural biology toward drug discovery with focus on protein-protein interaction and new target scouting. With the help of fragment-based screening, NMR-based SAR evaluation and X-ray crystallography, he designs molecules that can serve as chemical probes to validate new, therapeutic proof-of-concepts and that can be optimized into drug candidates. Since 2018, he has been developing artificial intelligence tools for drug discovery. This development is based on the integration of structural and chemical information into advanced analytical and generative machine-learning models. For his achievements in anti-parasitic drug discovery, he received the Helmholtz Gesellschaft Stifterverband Science Award–Erwin Schrödinger Prize in 2020. He is also an awardee of the Bavarian State Ministry of Economic Affairs pre-seed competition M4 Award (2019) and cofounder of several drug discovery companies.