Emerging electronic skins (E-Skins) offer continuous, real-time electrophysiological monitoring. However, daily mechanical scratches compromise their functionality, underscoring urgent need for self-healing E-Skins resistant to mechanical damage. Current materials have slow recovery times, impeding reliable signal measurement. The inability to heal within 1 minute is a major barrier to commercialization. A composition achieving 80% recovery within 1 minute has not yet been reported. Here, we present a rapidly self-healing E-Skin tailored for real-time monitoring of physical and physiological bioinformation. The E-Skin recovers more than 80% of its functionality within 10 seconds after physical damage, without the need of external stimuli. It consistently maintains reliable biometric assessment, even in extreme environments such as underwater or at various temperatures. Demonstrating its potential for efficient health assessment, the E-Skin achieves an accuracy exceeding 95%, excelling in wearable muscle strength analytics and on-site AI-driven fatigue identification. This study accelerates the advancement of E-Skin through rapid self-healing capabilities.

Wearable devices have received tremendous interest in healthcare monitoring due to their significant advantages in terms of flexibility, non-invasiveness, wireless capability, and portability. However, they still face challenges including the need for external power sources, bulky measuring instruments, and a lack of a wireless data transport system. Herein, we propose a PEDOT:PSS/MXene pressure sensing platform based on 2D e-textile and screen-printed interdigitated electrodes. Both materials improve the electrical conductivity, sensitivity, stability, flexibility, and mechanical durability of the pressure sensor. A near-field communication (NFC) readout system provides real-time wireless monitoring by transmitting signals from the sensor to a smartphone app, without external batteries. The pressure sensor has sensitivity, a wide detection range, excellent repeatability and stability, fast response/recovery time, and long-term durability. Long-term usability was verified through the bending test up to 21,400 cycles. The flexible pressure sensor successfully monitored wrist pulse, physical movements, and various muscle movements in the body. Repeatable, stable, reliable, and regular signals were obtained wirelessly through the NFC readout system. Our sensing platform could be a promising solution for healthcare monitoring, rehabilitation therapy, and early medical diagnosis. Additionally, it suggests a new platform for helping people with disabilities to communicate with others through human-machine interaction.