This paper presents an overview of the recent developments of modifier-adaptation schemes for real-time optimization of uncertain processes. These schemes have the ability to reach plant optimality upon convergence despite the presence of structural plant-model mismatch. Modifier Adaptation has its origins in the technique of Integrated System Optimization and Parameter Estimation, but differs in the definition of the modifiers and in the fact that no parameter estimation is required. This paper reviews the fundamentals of Modifier Adaptation and provides an overview of several variants and extensions. Furthermore, the paper discusses different methods for estimating the required gradients (or modifiers) from noisy measurements. We also give an overview of the application studies available in the literature. Finally, the paper briefly discusses open issues so as to promote future research in this area.

Cloud applications that offer data management services are emerging. Such clouds support caching of data in order to provide quality query services. The users can query the cloud data, paying the price for the infrastructure they use. Cloud management necessitates an economy that manages the service of multiple users in an efficient, but also, resource-economic way that allows for cloud profit. Naturally, the maximization of cloud profit given some guarantees for user satisfaction presumes an appropriate price-demand model that enables optimal pricing of query services. The model should be plausible in that it reflects the correlation of cache structures involved in the queries. Optimal pricing is achieved based on a dynamic pricing scheme that adapts to time changes. This paper proposes a novel price-demand model designed for a cloud cache and a dynamic pricing scheme for queries executed in the cloud cache. The pricing solution employs a novel method that estimates the correlations of the cache services in an time-efficient manner. The experimental study shows the efficiency of the solution.