Background: As recovery time of diabetic wound injury is prolonged by the production of detrimental factors, including reactive oxygen species (ROS) and inflammatory cytokines, attenuating the oxidative stress and inflammatory reactions in the microenvironment of the diabetic wound site would be significant. Experimental design: In our study, we prepared thermoreversible, antibacterial zeolite-based nanoparticles loaded hydrogel to promote diabetic wound healing via the neutralization of detrimental factors such as inflammatory cytokines and ROS. Results: The cerium (Ce)-doped biotype Linde type A (LTA) zeolite nanoparticles synergistically eliminated mitochondrial ROS and neutralized free inflammatory factors, thus remodeling the anti-inflammatory microenvironment of the wound and enhancing angiogenesis. Moreover, the thermoreversible hydrogel composed of Pluronic F127 and chitosan demonstrated strong haemostatic and bactericidal behavior. Conclusions: In conclusion, the obtained thermoreversible, antibacterial, zeolite-based nanoparticles loaded hydrogels represent a multi-targeted combination therapy for diabetic wound healing. Graphical

The LTA zeolite was coated on the GCE surface. RA was selectively adsorbed on the electrode and reacted on its surface, enhancing the electrochemical signal during the progress of DPV. The DPV results showed a good detection limit and recovery.

In this work, single-crystalline C₆₀ nanorods were synthesized by ultrasonic method in the C₆₀-saturated m-xylene solution. Materials characterizations of as-preapred C₆₀ nanorods were conducted by X-ray diffraction, scanning electron microscopy, transmission electron microscopy, selected area electron diffraction. Our results demonstrated that the single crystal structure of C₆₀ nanorods. The C₆₀ nanorods can be conveniently modified on the glassy carbon electrode. The electrochemical properties of C₆₀ nanorods towards glucose sensing were investigated by cyclic voltammetry method. The C₆₀ nanorods demonstrated a good electrochemical responses to glucose in aqueous solution. The linear relationship between glucose concentration and steady-state currents indicated that C₆₀-based carbon material can be considered a potential candidate for the design of biosensor.

Acetaminophen (AP) is a commonly used drug that has been detected in groundwater systems in many countries, and has received much attention from researchers in recent years due to its potential environmental impact. In this research, uniformly distributed boron nitride quantum dots (BNQDs) were prepared by a simple ultrasound-solvothermal method. Electrochemical luminescence (ECL) spectroscopy confirmed that BNQDs can act as an effective coreactant to create excellent efficiency in amplifying the ECL intensity of ruthenium-based ECL system. Based on the excited state of and the energy transfer quenching of AP oxidation products in the luminescent system, an AP concentration-quenched drug sensor was successfully constructed. For this sensor, a wide linear dynamic range and low detection limits (5.0 × 10⁻⁷−1.0 × 10⁻⁵ mol/L and 4.8 × 10⁻⁹ mol/L, respectively) were achieved. This ECL drug sensor has excellent performance in the accurate determination of AP content, relieving the stress of the previous AP detection process, and has good reproducibility and recovery in actual sample measurements.