J. Pierre Zila-Velasque

Dr. J. Pierre Zila-Velasque

Red Latinoamericana de Medicina en la Altitud e Investigación (REDLAMAI), Cerro de Pasco, Pasco, Peru
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Research Focus & Metrics

Academic Career Length

5Years (2022-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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Mario J. Valladares-GarridoMario J. Valladares-Garrido
Mario J. Valladares-Garrido
LZLuis E. Zapata-Castro
Luis E. Zapata-Castro
HDHelena Domínguez-Troncos
Helena Domínguez-Troncos
AGAbigaíl García-Vicente
Abigaíl García-Vicente
DFDarwin Anthony León Figueroa
Darwin Anthony León Figueroa
CDCristian Díaz-Vélez
Cristian Díaz-Vélez
Little has been studied in Peru on the mental health repercussions after a major earthquake. We aimed to explore the factors associated with depressive and anxiety symptoms in people who experienced a 6.1 magnitude earthquake in Piura, Peru, on 30 July 2021. A preliminary cross-sectional study was conducted in the general population between August–September 2021. An online questionnaire was provided using PHQ-9, GAD-7, and other relevant measures. Generalized linear models were applied. Of the 177 participants, the median age was 22 years, the majority were female (56%), and many experienced depressive (52%) or anxiety symptoms (52%). Presence of depressive symptoms was associated with a personal history of mental disorder, moderate housing damage, social/material support from politicians, moderate food insecurity, and insomnia. Presence of anxiety symptoms was associated with physical injury caused by the earthquake, mild food insecurity, and insomnia. The development of depressive and anxiety symptoms following the 2021 earthquake experienced in Piura depended on multiple individual and socioeconomic factors. Additional studies should reinforce the factors identified here given the methodological limitations, such as the study design, sampling method, and sample size. This would lead to effective intervention measures to mitigate the impact of earthquakes on mental health.
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27 June 2022 in Healthcare
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Mario J. Valladares-GarridoMario J. Valladares-Garrido
Mario J. Valladares-Garrido
CPCinthia Karina Picón-Reátegui
Cinthia Karina Picón-Reátegui
JZJ. Pierre Zila-Velasque
J. Pierre Zila-Velasque
PGPamela Grados-Espinoza
Pamela Grados-Espinoza
Studies in military personnel are scarce and have reported increased rates of medical consultations and insomnia. The COVID-19 pandemic has been associated with a number of factors that increase the prevalence of insomnia, which has established consequences in the military. However, reported data are from different settings. We aimed to identify the prevalence and factors associated with insomnia during the second COVID-19 epidemic wave in Lambayeque, Peru. A retrospective study in 566 participants was conducted face-to-face in November 2021. The dependent variable was insomnia, measured with the Insomnia Severity Index. The independent variables were socio-labor variables, physical activity, food insecurity, eating behavior disorder, fear of COVID-19, and resilience. The prevalence of insomnia was 23% (95% CI: 19.6–26.7%). In multivariate analysis, insomnia was associated with a personal history of mental health (PR: 1.71, 95% CI: 1.01–2.93), food insecurity (PR: 1.43, 95% CI: 1.05–1.95), fear of COVID-19 (PR: 2.57, 95% CI: 1.87–3.54), and high resilience (PR: 0.60, 95% CI: 0.42–0.86). Overall, the Peruvian military population presents a high prevalence of insomnia during the pandemic period. Special attention should be paid to factors that influence insomnia. Prevention and promotion programs should be established to reverse this negative trend in the military.

26 June 2023 in PLOS ONE
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JZJ. Pierre Zila-Velasque
J. Pierre Zila-Velasque
PGPamela Grados-Espinoza
Pamela Grados-Espinoza
KRKateriny Margot Regalado-Rodríguez
Kateriny Margot Regalado-Rodríguez
FSFrank Sosa-Nuñez
Frank Sosa-Nuñez
AAAbimegireysch Alcarraz-Jaime
Abimegireysch Alcarraz-Jaime
ASAnderson Nelver Soriano-Moreno
Anderson Nelver Soriano-Moreno
To identify sociodemographic and educational factors associated with mental health disorders in Peruvian medical students in clinical years. Cross-sectional study. We surveyed students from 24 Peruvian medical schools. We defined negative perception of educational environment as having a Dundee Ready Educational Environment Measure score below 100 points; we defined anxiety and depression as having more than 4 points on the Generalized Anxiety Disorder-7 and Patient Health Questionnaire-9 scales, respectively. Poisson regression with robust variance was used to assess the association between negative perception of educational environment and mental health alterations. Among the 808 participants, the prevalence of anxiety and depression symptoms was 77.6% and 67.3%, respectively. Negative perception of the educational environment was 31.6%. The factors associated with anxiety were being male (PR = 0.95, 95% CI:0.91–0.98), previous medical condition (Prevalence ratios PR = 1.10, 95% CI:1.05–1.16), previous diagnosis of coronavirus disease 2019 (PR = 0.93, 95% CI: 0.93–0.94), being from highlands (PR = 1.11, 95% CI: 1.05–1.16), studying at a national university (PR = 0.90, 95% CI: 0.88–0.92), and negative perception of the educational environment (PR = 1.04, 95% CI: 1.03–1.05), while factors associated with depression were being male (PR = 0.94, 95% CI: 0.93–0.95), previous medical condition (PR = 1.12, 95% CI: 1.08–1.17), type of university (national) (PR = 0.95, 95% CI: 0.95–0.96), and negative perception of the educational environment (PR = 1.11, 95% CI: 1.07–1.16). We found evidence that during the COVID-19 pandemic anxiety and depression are prevalent among Peruvian medical students. Sociodemographic factors and negative perception of educational environment were associated with the presence of these conditions.

Mario J. Valladares-GarridoMario J. Valladares-Garrido
Mario J. Valladares-Garrido
CPCinthia Karina Picón-Reátegui
Cinthia Karina Picón-Reátegui
JZJ. Pierre Zila-Velasque
J. Pierre Zila-Velasque
PGPamela Grados-Espinoza
Pamela Grados-Espinoza
CHCristian M. Hinostroza-Zarate
Cristian M. Hinostroza-Zarate
CPCésar Johan Pereira-Victorio
César Johan Pereira-Victorio
Military personnel represent a frontline group exposed to multiple stressors. These factors have increased during the COVID-19 pandemic, predisposing to the development of suicidal risk (SR). Given the few studies conducted in this population, we evaluated the prevalence of SR and its associated factors during the health emergency. A cross-sectional survey study was conducted in person among 514 participants in Lambayeque, Peru in 2021. The outcome was SR, and the exposures were depression (PHQ-9), anxiety (GAD-7), PTSD (PCL-C), and other sociodemographic variables. The prevalence of SR was 14.0% (95% CI: 11.12–17.31%) and was significantly higher in people with a family history of mental health (PR: 2.16; 95% CI: 1.13–4.15) and in those with moderate clinical insomnia (PR: 2.21; 95% CI: 1.19–4.12). Military personnel with high resilience had a lower prevalence of SR (PR: 0.54, CI: 0.31–0.95). Anxiety was associated with a higher prevalence of SR (PR: 3.27; 95% CI: 1.76–6.10). Our findings show that at least 1 out of 10 military personnel are at risk of suicide. Special attention should be paid to the associated factors to develop interventions and reverse their consequences. These results may be useful in policy implementation and general statistics of SR in the local and regional context.

24 September 2024 in PLOS ONE
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JZJ. Pierre Zila-Velasque
J. Pierre Zila-Velasque
PGPamela Grados-Espinoza
Pamela Grados-Espinoza
PGP. Alejandra Goicochea-Romero
P. Alejandra Goicochea-Romero
GTGustavo Tapia-Sequeiros
Gustavo Tapia-Sequeiros
JPJ. Enrique Pascual-Aguilar
J. Enrique Pascual-Aguilar
WNWendy Nieto-Gutierrez
Wendy Nieto-Gutierrez
Objective: Chronic and acute mountain sickness is known worldwide, but most of the available information comes from the eastern continent (Himalayas) without taking into account the west which has the most recent group located at altitude, the Andes. The aim of this study was to synthesize the evidence on the prevalence of acute and chronic mountain sickness in Latin American countries (LATAM). Methods: A systematic search of the variables of interest was performed until July 8, 2023 in the Web of Science, Scopus, PubMed and Embase databases. We included studies that assessed the prevalence of mountain sickness in high-altitude inhabitants (>1500 m.a.s.l) who lived in a place more than 12 months. These were analyzed by means of a meta-analysis of proportions. To assess sources of heterogeneity, subgroup analyses and sensitivity analyses were performed by including only studies with low risk of bias and excluding extreme values (0 or 10,000 ratio). PROSPERO (CRD42021286504). Results: Thirty-nine cross-sectional studies (10,549 participants) met the inclusion criteria. We identified 5 334 and 2 945 events out of 10,000 with acute and chronic mountain sickness in LATAM countries. The most common physiological alteration was polycythemia (2,558 events), while cerebral edema was the less common (46 events). Clinical conditions were more prevalent at high altitudes for both types of MS. Conclusion: Acute mountain sickness (AMS) occurs approximately in 5 out of 10 people at high altitude, while chronic mountain sickness (CMS) occurs in 3 out of 10. The most frequent physiological alteration was polycythemia and the least frequent was cerebral edema.

16 August 2023 in Heliyon
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Open access
JZJ. Pierre Zila-Velasque
J. Pierre Zila-Velasque
PGPamela Grados-Espinoza
Pamela Grados-Espinoza
WCW Samir Cubas
W Samir Cubas
MDMario Diaz-Barrera
Mario Diaz-Barrera
Josmel Pacheco-MendozaJosmel Pacheco-Mendoza
Josmel Pacheco-Mendoza
Congenital heart disease (CHD) is a severe childhood health problem worldwide. This study analyzes the scientific production on CHD published in Scopus during the last decade. This study assessed the research on CHD conducted during the 2011–2020 period. Indexed publications were identified using a list of keywords consisting of MeSH (Medical Subject Heading) and Emtree (EMBASE) terms for the category “Congenital Heart Defects.” The studies obtained were analyzed using the SciVal platform, and the production, impact, and collaboration indicators were considered. Additionally, an analysis of co-occurrence between countries and keywords was carried out with the VOSviewer software. The study found 8934 articles on CHD. A growing trend was observed during the last decade. The distribution of the scientific production at the international level shows that most publications are from the United States, China, and the United Kingdom, whereas Latin American countries have the lowest production. The articles analyzed contain a total of 89,835 citations. Most studies are published in high-impact journals (Q1), with 3273 studies corresponding to 39.3% of the total production analyzed. In the keyword analysis, we found five areas investigated. Scientific production has shown sustained growth in the past years. Increased scientific production in specific research areas may have helped decrease morbimortality due to CHD.