In vivo terahertz (THz) spectroscopy of pigmentary skin nevi is performed. The in vivo THz dielectric characteristics of healthy skin and dysplastic and non-dysplastic skin nevi are reconstructed and analyzed. The dielectric permittivity curves of these samples in the THz range exhibit significant differences that could allow non-invasive early diagnosis of dysplastic nevi, which are melanoma precursors. An approach for differentiating dysplastic and non-dysplastic skin nevi using the THz dielectric permittivity is proposed. The results demonstrate that THz pulsed spectroscopy is potentially an effective tool for non-invasive early diagnosis of dysplastic nevi and melanomas of the skin.

Pigmentary skin nevi are studied in vivo using terahertz pulsed spectroscopy. Dielectric parameters of healthy skin and dysplastic and nondysplastic nevi are reconstructed and analyzed. The fact that

An approach for automatic construction of the wavelet-domain de-noising

A complex approach was proposed for early diagnosis of skin melanoma. The approach includes sequential examinations of skin lesions using several imaging systems. A focus is placed on the specifics of morphometry using clinical images of skin neoplasms, features of imaging systems, and main steps of automated image processing and image recognition to diagnose melanoma. Metrological features were described for the approach; errors of measuring the clinical parameters of skin neoplasms did not exceed the allowable error level. The approach was tested, and the sensitivity and specificity of the methods employed was found to be higher than 90%.