Dr. Stephen Riordan
1. Gastrointestinal and Liver Unit, Prince of Wales Hospital, Sydney, NSW 2031, Australia
+1
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Academic Career Length
34Years (1993-Present)
(Calculated once Scilit publication data is synced: current year − year of first publication + 1)
Representative Publications
View All Publications20 November 2008 in Hepatology International
Journal Article
SSShiv Kumar Sarin
Shiv Kumar SarinAKAshish Kumar
Ashish KumarJAJohn A. Almeida
John A. AlmeidaYCYogesh Kumar Chawla
Yogesh Kumar ChawlaSFSheung Tat Fan
Sheung Tat FanMYMan-Fung Yuen
Man-Fung Yuen +21
The Asian Pacific Association for the Study of the Liver (APASL) set up a working party on acute-on-chronic liver failure (ACLF) in 2004, with a mandate to develop consensus guidelines on various aspects of ACLF relevant to disease patterns and clinical practice in the Asia-Pacific region. Experts predominantly from the Asia–Pacific region constituted this working party and were requested to identify different issues of ACLF and develop the consensus guidelines. A 2-day meeting of the working party was held on January 22–23, 2008, at New Delhi, India, to discuss and finalize the consensus statements. Only those statements that were unanimously approved by the experts were accepted. These statements were circulated to all the experts and subsequently presented at the Annual Conference of the APASL at Seoul, Korea, in March 2008. The consensus statements along with relevant background information are presented in this review.
1 November 2006 in Journal of Hepatology
Journal Article
Stephen RiordanRWRoger Williams
Roger Williams
1 January 2006 in World Journal of Gastroenterology
Journal Article
JAJohn Almeida
John Almeida
SGSumedha Galhenage
Sumedha Galhenage
JYJennifer Yu
Jennifer YuJKJelica Kurtovic
Jelica Kurtovic
Stephen RiordanIncreasing evidence suggests that derangement of gut flora is of substantial clinical relevance to patients with cirrhosis. Intestinal bacterial overgrowth and increased bacterial translocation of gut flora from the intestinal lumen, in particular, predispose to an increased potential for bacterial infection in this group. Recent studies suggest that, in addition to their role in the pathogenesis of overt infective episodes and the clinical consequences of sepsis, gut flora contributes to the pro-inflammatory state of cirrhosis even in the absence of overt infection. Furthermore, manipulation of gut flora to augment the intestinal content of lactic acid-type bacteria at the expense of other gut flora species with more pathogenic potential may favourably influence liver function in cirrhotic patients. Here we review current concepts of the various inter-relationships between gut flora, bacterial translocation, bacterial infection, pro-inflammatory cytokine production and liver function in this group.
1 July 2006 in Inflammation Research
Journal Article
Stephen RiordanNSN. A. Skinner
N. A. Skinner
JKJ. Kurtovic
J. Kurtovic
SLS. Locarnini
S. Locarnini
CMC. J. McIver
C. J. McIver
KVK. Visvanathan
K. Visvanathan +1
1 August 2006 in Clinical and Vaccine Immunology
Journal Article
Stephen RiordanNSNarelle Skinner
Narelle Skinner
JKJelica Kurtovic
Jelica Kurtovic
SLStephen Locarnini
Stephen Locarnini
KVKumar Visvanathan
Kumar VisvanathanPersistent infection with hepatitis B virus (HBV) likely depends on viral inhibition of host defenses. We report that chronic hepatitis B e antigen-positive HBV infection is associated with a significant reduction in peripheral blood monocyte expression of Toll-like receptor 2, a key component of innate immunity, thereby providing a mechanism by which wild-type HBV may establish persistent infection.
1 September 1996
Journal Article
Stephen RiordanCMC J McIver
C J McIver
BWB M Walker
B M Walker
VDV M Duncombe
V M Duncombe
TBT D Bolin
T D Bolin
MTM C Thomas
M C Thomas
About Me
Stephen Riordan is a professor of medicine (conjoint) at the Prince of Wales Clinical School, Faculty of Medicine, University of New South Wales, and head of the Gastrointestinal and Liver Unit at the Prince of Wales Hospital, a university teaching hospital, in Sydney, Australia. He holds appointments as senior staff specialist in gastroenterology and hepatology at the Prince of Wales Hospital and its affiliated Sydney Children’s Hospital and Royal Hospital for Women (also university teaching hospitals) and as a consultant physician, gastroenterologist, and hepatologist at the Prince of Wales Private Hospital. His undergraduate training in medicine was at the University of New South Wales in Sydney, Australia, from which he graduated with honours. He was among several clinicians and researchers profiled at the 2014 Annual Scientific Meeting of the American Association for the Study of Liver Diseases, held in Boston, Massachusetts, and also at the 2015 Annual Scientific Meeting of the American Association for the Study of Liver Diseases, held in San Francisco, California. His research interests include gastroenterology and hepatology.