Background: Electronic medical records (EMRs) contain a wealth of information related to breast cancer diagnosis and treatment. Extracting relevant features from these medical records and constructing a knowledge graph can significantly contribute to an efficient data analysis and decision support system for breast cancer diagnosis. Methods: An approach was proposed to develop a workflow for effectively extracting breast cancer-related features from Chinese breast cancer mammography reports and constructing a knowledge graph for breast cancer diagnosis. Firstly, the concept layer of the knowledge graph for breast cancer diagnosis was constructed based on breast cancer diagnosis and treatment guidelines, along with insights from clinical experts. .Next, a BiLSTM-Highway-CRF model was designed to extract the mammography features, which formed the data layer of the knowledge graph. Finally, the knowledge graph was constructed by combining the concept layer and the data layer in a Neo4j graph data platform, and then applied in visualization analysis, semantic query and computer assisted diagnosis. Results: Mammographic features were extracted from a total of 1171 mammography examination reports. The overall extraction performance of the model achieved an accuracy rate of 97.16%, a recall rate of 98.06%, and a F1 score of 97.61%. Additionally, 47,660 relationships between entities were identified based on the four different types of relationships defined in the concept layer. The knowledge graph for breast cancer diagnosis was constructed after inputting mammographic features and relationships into the Neo4j graph data platform. The model was assessed from the concept layer, data layer, and application layer perspectives, and showed promising results. Conclusions: The proposed workflow is applicable for constructing knowledge graphs for breast cancer diagnosis based on Chinese EMRs. This study serves as a reference for the rapid design, construction, and application of knowledge graphs for diagnosis and treatment of other diseases. Furthermore, it offers a potential solution to address the issues of limited data sharing and format inconsistencies present in Chinese EMR data.
22 February 2024 in Artificial Intelligence in Medicine
The first task for eradicating poverty is accurate poverty identification. Deep poverty identification is conducive to investing resources to help deeply poor populations achieve prosperity, one of the most challenging tasks in poverty eradication. This study constructs a deep poverty identification model utilizing explainable artificial intelligence (XAI) to identify deeply poor households based on the data of 23,307 poor households in rural areas in China. For comparison, a logistic regression-based model and an income-based model are developed as well. We found that our XAI-based model achieves a higher identification performance in terms of the area under the ROC curve than both the logistic regression-based model and the income-based model. For each rural household, the odds of being identified as deeply poor are obtained. Additionally, multidimensional household characteristics associated with deep poverty are specified and ranked for each poor household, while ordinary feature ranking methods can only provide ranking results for poor households as a whole. Taking all poor households into consideration, we found that common important characteristics that can be used to identify deeply poor households include household income, disability, village attributes, lack of funds, labor force, disease, and number of household members, which are validated by mutual information analysis. In conclusion, our XAI-based model can be used to identify deep poverty and specify key household characteristics associated with deep poverty for individual households, facilitating the development of new targeted poverty reduction strategies.
At present, span-based entity recognition methods are mainly used to accurately identify the span (entity) boundary for entity recognition, in which the relative position information of the span boundary and the information of words in the span region are routinely ignored. This information can be used to improve entity recognition performance. Therefore, a nested entity recognition model, which integrates the relative position information of the span and the region information within the span, is proposed. The span representation is first obtained with a triaffine attention. Then, the relative position of the span boundary and the word information in the span region, as well as the previous span representation, are fused to obtain a new label-level span representation with another triaffine attention. Finally, the span (entity) recognition task is carried out by a cooperative biaffine mechanism. Experiments were conducted on some public datasets, including ACE2004, ACE2005 and GENIA. The results show that the F1-scores achieved using the proposed method were 87.66%, 86.86% and 80.90% on ACE2004, ACE2005 and GENIA, respectively. These experiments show that the method achieved state-of-the-art (SOTA) results. Moreover, the proposed model has fewer parameters and needs fewer resources with a lower time complexity than the existing triaffine mechanism model.
Objectives: This study aims to investigate whether different types of electronic health record (EHR) users have distinct preferences for data quality assessment indicators (DQAI) and explore how these preferences can guide the enhancement of EHR systems and the optimization of related policies. Materials and Methods: High-frequency indicators were identified by a systematic literature review to construct a DQAI system, which was assessed by a user-oriented investigation involving doctors, nurses, hospital supervisors, and clinical researchers. The entropy weight method and fuzzy comprehensive evaluation model were employed for the system comprehensive evaluation. Exploratory factor analysis was used to construct dimensions, and visualization analysis was utilized to explore preferences at both the indicator and dimension levels. Results: Sixteen indicators were identified to construct the DQAI system and grouped into 2 dimensions: structural and relational. The DQAI system achieved a comprehensive evaluation score of 90.445, corresponding to a “very important” membership level (62.5%). Doctors and nurses exhibited a higher score mean (4.43-4.66 out of 5) than supervisors (3.73-4.55 out of 5). Researchers emphasized credibility, with a score mean of 4.79 out of 5. Discussion: The findings reveal that different types of EHR users exhibit distinct preferences for the DQAI at both indicator and dimension levels. Doctors and nurses thought that all indicators were important, clinical researchers emphasized credibility, and supervisors focused mainly on accuracy. Indicators in the relational dimension were generally more valued than structural ones. Doctors and nurses prioritized indicators of relational dimension, while researchers and supervisors leaned towards indicators of structural dimension. These insights suggest that tailored approaches in EHR system development and policy-making could enhance EHR data quality. Conclusion: This study underscores the importance of user-centered approaches in optimizing EHR systems, highlighting diverse user preferences at both indicator and dimension levels.