The Seven Countries Study showed that traditional Japanese and Mediterranean diets are protective against cardiovascular diseases (CVDs). The Japanese diet is considered the healthiest because it provides Japanese populations with the highest longevity and health. DASH and Mediterranean-style diets are also considered healthy diets, although the Indo-Mediterranean-style diet may provide better protective effects among patients with CVDs compared to other diets. The concept of the Indo-Mediterranean type of diet was developed after examining its role in the prevention of CVDs in India, the value of which was confirmed by a landmark study from France: the Lyon Heart Study. These workers found that consuming an alpha-linolenic acid-rich Mediterranean-style diet can cause a significant decline in CVDs and all-cause mortality. Later in 2018, the PREDIMED study from Spain also reported that a modified Mediterranean-style diet can cause a significant decline in CVDs, type 2 diabetes mellitus (T2DM), and cancer. The Indo-Mediterranean diet may be superior to DASH and Mediterranean diets because it contains millets, porridge, and beans, as well as spices such as turmeric, cumin, fenugreek, and coriander, which may have better anti-inflammatory and cardioprotective effects. These foods are rich sources of nutrients, flavonoids, calcium, and iron, as well as proteins, which are useful in the prevention of under- and overnutrition and related diseases. It is known that DASH and Mediterranean-style diets have a similar influence on CVDs. However, the Indo-Mediterranean-style diet may be as good as the Japanese diet due to improved food diversity and the high content of antioxidants.
28 February 2025 in Indian Journal of Clinical Biochemistry
Heart failure (HF) has become a public health problem, but exact pathophysiology is still unknown. Western diet characterised with high sugar, high fat, red meat and processed meat, eggs, fried foods and sweetened beverages, may cause oxidative stress and inflammation, leading to oxidative dysfunction and adverse effects on cardiac-ultra-structure. However, only little is known about oxidative function of the of the myocardium and how oxidative dysfunction predispose Ca-overloading resulting in to physio-pathological remodelling leading to HF. Antioxidants such as flavonoids and polyphenolics, omega-3 fatty acids, vitamins, minerals as well as essential and nonessential amino acids that are rich in Indo-Mediterranean type of diets, may have protective roles in maintaining oxidative functions of the heart. The cardiac cells use fatty acids and glucose for the metabolic functions depending upon physiological and metabolic requirements. Apart from glucotoxicity, lipotoxicity is also damaging to cardiac cells which worsen in presence of deficiency of endogenous antioxidants and lower exogenous antioxidants in the diet. There is increased production of ceramide, advanced glycation end products (AGE) and triamino-methyl-N-oxide (TMAO) due to high sugar and high fat diets, leading to oxidative dysfunction and Ca-overloading. The biological changes may begin with physiological remodelling to pathological remodelling due to oxidative damages. High fat diet in combination with inducible nitric oxide synthase (NOSi) via N-arginine methyl ester has been found to preserve ejection fraction in a mouse model of HF. It is possible that increased supplementation of High Exogenous Antioxidant Restorative Treatment (HEART) diet; polyphenolics and flavonoids, vitamins, minerals, arginine, with omega-3 fatty acids, and cessation of red meat and egg may further improve the oxidative function of cardiac cells, resulting in the prevention and improvement in the earliest of the Six Stages of HF. Cohort studies and randomised, controlled trials would be necessary for demonstration of the role of HEART diet in the management of HF.
1 January 2021 in Municipal education: innovations and experiment
В статье анализируются особенности питания как одного из важных факторов здоровья современных школьников. Отмечается, что важнейшим аспектом является поведение самих школьников в отношении питания, знание и соблюдение ими правил здорового питания. Цель. Выявление особенностей самооценки здоровья и пищевого поведении учащихся школ в отдельных регионах. Научная новизна. Исследованы пищевые привычки школьников в Дагестане, Москве и Тюмени в части рациона питания, потребления напитков, сладких блюд и др. Выявлены как общие для всех, так и характерные для регионов проблемы в поведении подростков в сфере питания. Обнаружено, что более 70% респондентов не соблюдает какой-либо последовательности при приеме пищи, большинство пьет воду после еды и склонно ежедневно потреблять сладкое. Замечено, что в школах с более здоровым пищевым поведением подростки лучше оценивают свое здоровье. Данные и методы. При написании статьи использовались данные диспансеризации школьников, пилотного опроса подростков 14-17 лет в школах указанных регионов России, проведенного с помощью Google анкеты, графоаналитические методы, сравнительный анализ. Практическая значимость. Исследование будет полезно при разработке политики по сохранению здоровья школьников на федеральном и региональном уровнях, а также для педагогов, родителей и...
1 January 2021 in Municipal education: innovations and experiment
В статье рассматривается концепция здоровьесберегающего пространства современного образовательного учреждения, интегратором которой предлагается метаконцепт «человек-культура». Цель. Выявление условий создания здоровьесберегающего межэтнического культурного образовательного пространства в условиях современного общества. Методика и методы. Использованы методологические компетентностный и метапредметный подходы, рассматриваются возможности интегративных предметов «Музыка», «Естествознание», «История мировой культуры» для применения межэтнического культурного опыта при решении данной проблемы. Научная новизна. В статье сделана попытка раскрыть роль взаимодействия науки и искусства на примере академической музыки в жизни человека. Обосновывается необходимость создания интегративных программ естественнонаучного и музыкального образования для решения проблем духовного, нравственного и физического здоровья обучающихся. Даются рекомендации для сохранения этнокультурности, как фактора эффективного существования личности в условиях глобализации. Практическая значимость. Приводятся примеры эффективных метапредметных практик и метакогнитивных технологий для формирования межэтнического культурного образовательного пространства как здоровьесберегающего. Предлагаются варианты решения проблемы ухудшения здоровья у детей и подростков на основе реализации методических разработок занятий и программ в рамках данной...
Western diet and lifestyle are known to predispose to low-grade chronic systemic inflammation, leading to dementia and coronary artery disease (CAD). It is hypothesized that dementia may also predispose individuals to CAD, just as it is well-established that CAD can predispose individuals to dementia. This study investigates the association between dementia and the risk of developing CAD. All participants (n = 2,002) were over 25 years old (986 females and 1,016 males), and all were residing in urban areas. Validated instruments, including a modified memory impairment scale, were used to assess dementia. The association between memory dysfunction and CAD was evaluated through regression analysis. Definite memory dysfunction was found in 4.54% of participants, with a higher prevalence in men than in women, and was more common than possible memory dysfunction. Regression analysis, after adjusting for age and body mass index, revealed that dementia scores were significantly associated with CAD risk (p<0.001) in both men (odds ratio [OR]: 0.90, 95% confidence interval [CI]: 0.82 – 0.98) and women (OR: 0.88, CI: 0.81 – 0.96). Similarly, diabetes mellitus scores were strongly associated with CAD risk (p<0.001) in men (OR: 0.76, CI: 0.68 – 0.87) and women (OR: 0.77, CI: 0.77 – 0.87). Sedentary behavior and tobacco use were also positively associated with CAD in both genders (p<0.05), whereas alcoholism showed a modest positive association with CAD risk in men but not in women. These findings suggest a potential association between dementia and CAD risk across genders. However, larger cohort studies are needed to confirm these results.