Marie Gernigon

Dr. Marie Gernigon

1. CIAMS, Université Paris-Saclay, CEDEX, 91405 Orsay, France
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orcid

Research Focus & Metrics

Academic Career Length

5Years (2022-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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JGJérôme Grondin
Jérôme Grondin
VCVincent Crenn
Vincent Crenn
MGMarie Gernigon
Marie Gernigon
YQYonis Quinette
Yonis Quinette
BLBastien Louguet
Bastien Louguet
Marc DautyMarc Dauty
Marc Dauty
After anterior cruciate ligament reconstruction (ACLR), a progressive process is followed from rehabilitation to the return to sport including a crucial step known as the return to running. Return to running (RTR) can be predicted by an isokinetic knee strength assessment at 4 months post-surgery. All patients who had primarily undergone ACLR with a hamstring autograft procedure between 2010 and 2020 were included in this study. Four months after surgery, patients were evaluated using an isokinetic knee strength test. Patients were monitored until the 6th month post-surgery to see if they had returned to running. Comparisons were carried out between the two groups—the RTR and the no-RTR. A multivariate logistic regression analysis was used to predict the RTR status from explicative parameters. Receiver Operating Characteristic (ROC) curves were established to identify cutoffs with their characteristics. A total of 413 patients were included and 63.2% returned to running at 4 months post-surgery. The mean Lysholm score, knee complication rate, and isokinetic parameters were statistically different between both groups. Using a multivariate logistic regression model and ROC curves, the best isokinetic parameter to assist with the decision to allow an RTR was the quadriceps limb symmetry index at 60°/s with a cutoff of 65%. The hamstring LSI at 180°/s could be added (cutoff of 80%) to slightly increase the prediction of an RTR. Quadriceps strength normalized to body weight at 60°/s is a useful parameter (cutoff: 1.60 Nm/kg) but measurements on both sides are necessary. Isokinetic parameters are objective parameters to allow a return to running at 4 months after ACLR with a hamstring procedure.

10 July 2022 in Sensors
Verified
Journal Article
Open access
PDF file
JDJulien DESANLIS
Julien DESANLIS
DGDan Gordon
Dan Gordon
CCCamille CALVEYRAC
Camille CALVEYRAC
FCFrançois Cottin
François Cottin
MGMarie Gernigon
Marie Gernigon
(1) Background: Near-infrared spectroscopy (NIRS) is an innovative and non-invasive technology used to investigate muscular oxygenation. The aim of this study is to assess the within- and between-session reliability of the NIRS Portamon (Artinis, Elst, Netherlands) device following three sets of induced muscle ischemia. (2) Methods: Depending on the experimental group (G1, G2 or G3), a cuff was inflated three times on the left upper arm to 50 mmHg (G1), systolic blood pressure (SBP) + 50 mmHg (G2) or 250 mmHg (G3). Maximum, minimum and reoxygenation rate values were assessed after each occlusion phase, using a Portamon device placed on the left brachioradialis. Reliability was assessed with intraclass correlation coefficient (ICC) value and ICC 95% confidence interval (CI-95%), coefficient of variation (CV) and standard error of measurement (SEM) (3) Results: Our results showed a good to excellent reliability for maximums and minimums within-session. However, the reoxygenation rate within sessions as well as measurements between sessions cannot predominantly show good reliability. (4) Conclusions: Multiple measurements of maximums and minimums within a single session appeared to be reliable which shows that only one measurement is necessary to assess these parameters. However, it is necessary to be cautious with a comparison of maximum, minimum and reoxygenation rate values between sessions.

9 May 2022 in Sensors
Verified
Journal Article
Open access
PDF file
MCMarie Chantrelle
Marie Chantrelle
PMPierre Menu
Pierre Menu
MGMarie Gernigon
Marie Gernigon
BLBastien Louguet
Bastien Louguet
Marc DautyMarc Dauty
Marc Dauty
Alban Fouasson-ChaillouxAlban Fouasson-Chailloux
Alban Fouasson-Chailloux
Patellar tendinopathy (PT) in professional volleyball players can have an impact on their careers. We evaluated the impact of this pathology in this specific population in terms of isokinetic strength and jumping performances. Thirty-six professional male volleyball players (mean age: 24.8 ± 5.2) performed isokinetic knee assessments, single-leg countermovement jumps and one leg hop test. They filled out the Victorian Institute of Sport Assessment-Patella (VISA-P) score. Two groups were assessed: “PT group” (n = 15) and “control group” (n = 21). The VISA-P score was lower in the PT group (p < 0.0001). No difference was found between the isokinetic strength limb symmetry index and the jump performance limb symmetry index. The healthy legs of the control group were compared with the affected (PT+) and the unaffected legs (PT−) of the PT group. Compared with the healthy legs, both PT+ and PT− legs showed decreased values of quadriceps and hamstring strengths. Only PT+ legs scored lower than healthy legs in countermovement jumps and hop tests. No differences were found between PT+ and PT− legs for muscle strengths and jumps. A low correlation existed between quadriceps strength and jumping performances (r > 0.3; p < 0.001). Volleyball players with PT showed a decrease in the isokinetic knee strength. This strength deficit was found both on the symptomatic legs and the asymptomatic ones. Jumps were only significantly altered on the pathological legs. Highlighting that the unaffected limbs were also impaired in addition to the affected limbs may help provide a better adaptation of the rehabilitation management.

VMViviane Merzbach
Viviane Merzbach
MFMichael Ferrandino
Michael Ferrandino
MGMarie Gernigon
Marie Gernigon
Jorge Miguel Madeira Marques PintoJorge Miguel Madeira Marques Pinto
Jorge Miguel Madeira Marques Pinto
ASAdrian Scruton
Adrian Scruton
DGDan Gordon
Dan Gordon
The duplication of chromosome 21, as evidenced in Down Syndrome (DS), has been linked to contraindications to health, such as chronotropic and respiratory incompetence, neuromuscular conditions, and impaired cognitive functioning. The purpose of this study was to examine the effects of eight weeks of prescribed exercise and/or cognitive training on the physical and cognitive health of adults with DS. Eighty-three participants (age 27.1 ± 8.0 years) across five continents participated. Physical fitness was assessed using a modified version of the six-minute walk test (6MWT), while cognitive and executive functions were assessed using the Corsi block test, the Sustained-Attention-To-Response Task (SART), and the Stroop task (STROOP). All were completed pre- and post-intervention. Participants were assigned to eight weeks of either exercise (EXE), 3 × 30 min of walking/jogging per week, cognitive training (COG) 6 × ~20 min per week, a combined group (COM), and a control group (CON) engaging in no intervention. 6MWT distance increased by 11.4% for EXE and 9.9% for COM (p < 0.05). For SART, there were positive significant interactions between the number of correct and incorrect responses from pre- to post-intervention when participants were asked to refrain from a response (NO-GO-trials) across all experimental groups (p < 0.05). There were positive significant interactions in the number of correct, incorrect, and timeout incompatible responses for STROOP in EXE, COG, and COM (p < 0.05). Walking generated a cognitive load attributed to heightened levels of vigilance and decision-making, suggesting that exercise should be adopted within the DS community to promote physical and cognitive well-being.

24 January 2024 in International Journal of Sports Medicine
Verified
Journal Article
Closed access
PDF file
MDMarc Dauty
Marc Dauty
PCPhilippe Combes
Philippe Combes
MGMarie Gernigon
Marie Gernigon
PMPierre Menu
Pierre Menu
VCVincent Crenn
Vincent Crenn
Alban Fouasson-ChaillouxAlban Fouasson-Chailloux
Alban Fouasson-Chailloux
Different grafting procedures are available to restore knee stability after revision anterior cruciate ligament (ACL) reconstruction. We compared knee strength recovery between ACL revision surgery and primary reconstruction. One hundred and ten patients with ACL revision surgery were matched with 110 patients with primary reconstruction based on the graft procedure. The isokinetic knee strength had been assessed for the first 9 months post-surgery. Knee laxity, function, and activity score were also evaluated. Limb symmetry index for knee extensor and flexor strength was not different at 4-, 6- and 9-months post-surgery between revision surgery and primary reconstruction. These results depended on ipsilateral or contralateral graft choice. Ipsilateral hamstring tendon (HT) and contralateral bone-patellar-tendon-bone (BPTB) graft procedures were similar for a revision of a BPTB graft failure. Contralateral HT procedure was better than ipsilateral BPTB procedure for a revision of a HT graft failure. The early recovery of isokinetic knee strength after ACL revision surgery regardless of the HT or BPTB procedures, was similar to the recovery after primary ACL reconstruction with the same graft technique. These results apparently depended on a temporary quadriceps arthrogenic muscle inhibition and on a persistent donor site morbidity, concerning the new and the previous grafts, respectively.

1 January 2025 in HAL
Verified
Preprint
Open access
PDF file
AGAbdelbaki Guir
Abdelbaki Guir
CFChloe French
Chloe French
DRDan Robbins
Dan Robbins
DGDan Gordon
Dan Gordon
MGMarie Gernigon
Marie Gernigon
MTMeriem Taous
Meriem Taous
This study investigates the correlation between Near-Infrared Spectroscopy (NIRS) and transcutaneous oxygen pressure (T cP O 2 ) for monitoring tissue oxygenation and wound healing progression in diabetic feet. Signal-derived features, including area under the curve (AUC), reperfusion recovery speed, and peak amplitudes, were extracted and analyzed longitudinally to assess healing trajectories. The results demonstrate that NIRS and T cP O 2 measurements provide complementary insights into microvascular function and can serve as reliable indicators of wound healing status. These findings highlight the potential of integrating non-invasive, signal-based monitoring techniques into personalized diabetic foot care and clinical decision making.