Stretchable skin sensor patch tailored for submental areas is developed for remote management of swallowing disorders.

Electroretinogram examinations serve as routine clinical procedures in ophthalmology for the diagnosis and management of many ocular diseases. However, the rigid form factor of current corneal sensors produces a mismatch with the soft, curvilinear, and exceptionally sensitive human cornea, which typically requires the use of topical anesthesia and a speculum for pain management and safety. Here we report a design of an all-printed stretchable corneal sensor built on commercially-available disposable soft contact lenses that can intimately and non-invasively interface with the corneal surface of human eyes. The corneal sensor is integrated with soft contact lenses via an electrochemical anchoring mechanism in a seamless manner that ensures its mechanical and chemical reliability. Thus, the resulting device enables the high-fidelity recording of full-field electroretinogram signals in human eyes without the need of topical anesthesia or a speculum. The device, superior to clinical standards in terms of signal quality and comfortability, is expected to address unmet clinical needs in the field of ocular electrodiagnosis.

A thin transparent wearable patch with silicon nanoneedles is developed for efficient interface with biological cells and tissues.

Electroactive polymer (EAP) is a polymer that reacts to electrical stimuli, such as voltage, and can be divided into electronic and ionic EAP by an electrical energy transfer mechanism within the polymer. The mechanism of ionic EAP is the movement of the positive ions inducing voltage change in the polymer membrane. Among the ionic EAPs, an ionic polymer–metal composite (IPMC) is composed of a metal electrode on the surface of the polymer membrane. A common material for the polymer membrane of IPMC is Nafion containing hydrogen ions, and platinum, gold, and silver are commonly used for the electrode. As a result, IPMC has advantages, such as low voltage requirements, large bending displacement, and bidirectional actuation. Manufacturing of IPMC is composed of preparing the polymer membrane and plating electrode. Preparation methods for the membrane include solution casting, hot pressing, and 3D printing. Meanwhile, electrode formation methods include electroless plating, electroplating, direct assembly process, and sputtering deposition. The manufactured IPMC is widely demonstrated in applications such as grippers, micro-pumps, biomedical, biomimetics, bending sensors, flow sensors, energy harvesters, biosensors, and humidity sensors. This paper will review the overall field of IPMC by demonstrating the categorization, principle, materials, and manufacturing method of IPMC and its applications.

This soft machine can pick up and release an ultrathin “living” cell sheet and electronics without crumpling.

People with hand amputations experience strenuous daily life challenges, often leading to lifelong use of a prosthetic hand(s) and services. Modern advanced prosthetic hands must be able to provide human hand-like sensory perceptions to receive external stimuli during daily activities while simultaneously replicating a realistic appearance and physical properties to naturally integrate in social contexts; however, the practical realization of these issues are impeded by a lack of effective methodologies. Herein, we present an optimal set of materials, design layouts, and fabrication schemes to construct an easy-to-wear seamless electronic glove (e-glove) suitable for arbitrary hand shapes that provides all of the desired human hand-like features. The system configuration involves a connection to a control wristwatch unit for real-time display of sensory data measured and remote transmission to the user. The experimental and computational studies provide details regarding the underlying principles of the materials selection, mechanics design, and operational management of the entire system. The demonstration of the e-glove system in interactions with human subjects illustrates the utility, comfort, and convenience of this device.