Dean David Ad-El

Prof. Dean David Ad-El


Research Focus & Metrics

Academic Career Length

26Years (2001-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

View All Publications
1 June 2004 in Plastic and Reconstructive Surgery
Verified
Journal Article
Closed access
AZArik Zaretski
Arik Zaretski
AAAharon Amir
Aharon Amir
IMIsaac Meller
Isaac Meller
DLDavid Leshem
David Leshem
YKYehuda Kollender
Yehuda Kollender
EGEyal Gur
Eyal Gur
The fibula free flap became popular in orthopedic oncology for limb-sparing long bone tumor resection. It is particularly suitable for intercalary or resection arthrodesis options. In the present series, a surgical reconstruction algorithm was used, enabling each patient to receive a personalized technique. During the years 1998 to 2002, 30 patients underwent limb-sparing surgery for long bone sarcoma. There were 18 males and 12 females. Their mean age was 23 years (range, 9 to 70 years). The diagnoses were Ewing's sarcoma (11 patients), osteogenic sarcoma (eight patients), chondrosarcoma (five patients), giant cell tumor of bone (three patients), high-grade soft-tissue sarcoma (two patients), and leiomyosarcoma of bone (one patient). The majority of tumors where located in the lower extremity (23 patients), mostly in the femur (15 patients with four tumors in the proximal femoral shaft, five tumors in the distal femoral shaft, five tumors in the whole femoral shaft, and one tumor in the proximal femoral head). In seven patients, the upper extremity was involved; in six patients, the radius was involved; and in one patient, the humerus was involved. The free fibula flap was used in three types of approaches: vascularized fibula as an osseous flap only (18 patients), a combination of a vascularized fibula flap in conjunction with an allo-graft (Capanna's technique; 10 patients), and a free double-barreled fibula (two patients). All flaps survived. Postoperatively, all patients were monitored clinically, radiologically, and by radioisotope bone scan studies. Callus formation and union were shown 2.6 to 8 months postoperatively. Patients who underwent lower extremity reconstruction were nonweightbearing for 3 to 9 months, with a transition period in which they used a brace and gradually increased weightbearing until full weightbearing was achieved. Eight patients had 11 recipient-site complications. Two patients (6.7 percent) had hematomas, and three patients (10 percent) had infection and dehiscence of the surgical wound with bone exposure in one patient; all complications resolved with conservative treatment only. Failure of the hardware fixation system occurred in two patients, mandating surgical correction. No fibula donor-site complications were recorded. In intercalary resections, the use of the vascularized fibula flap as an isolated osseous flap might be insufficient. Different body sites have different stress loads to carry, depending on the age of the patient and on his individual physical status. To achieve initial strength in the early period, the authors combined the free fibula flap with an allograft (Capanna's method) or augmented it as a double-barreled fibula. They propose a surgical algorithm to assist the surgeon with the preferred method for reconstruction of various long bone defects in different body locations at childhood or adulthood. Long bone reconstruction using a vascularized fibula flap, alone or in combination with an allograft, autogenous bone graft, or double-barreled fibula for limb-sparing surgery, is a safe and reliable method with a predictable bony union, good functional outcome, and a low complication rate.

1 February 2006 in Journal of Investigative Dermatology
Verified
Journal Article
Closed access
SAShani Avniel
Shani Avniel
ZAZaretski Arik
Zaretski Arik
AMAlex Maly
Alex Maly
ASAssa Sagie
Assa Sagie
HBHanna Ben Basst
Hanna Ben Basst
APAMNON PELED
AMNON PELED

1 March 2021 in Journal of Investigative Dermatology
Verified
Journal Article
Closed access
AAAnna Aronovich
Anna Aronovich
LMLilach Moyal
Lilach Moyal
BGBatia Gorovitz
Batia Gorovitz
IAIris Amitay-Laish
Iris Amitay-Laish
HNHadas Prag Naveh
Hadas Prag Naveh
EHEmmilia Hodak
Emmilia Hodak

1 July 2006 in Plastic and Reconstructive Surgery
Verified
Journal Article
Closed access
SMSagit M.D. Meshulam-Derazon
Sagit M.D. Meshulam-Derazon
SNShira M.D. Nachumovsky
Shira M.D. Nachumovsky
DADean David Ad-El
Dean David Ad-El
JSJaqueline Sulkes
Jaqueline Sulkes
DHDaniel J. M.D. Hauben
Daniel J. M.D. Hauben
Background: Improvements in burn care during the last two decades call for new prediction models of morbidity and mortality. The aim of the study was to identify parameters that are predictive of major morbidity factors and risk of mortality in patients with burn injury. Methods: The charts of 249 patients (236 survivors) aged 1 to 94 years who were treated for second- and third-degree burns from 1995 to 2002 were reviewed. A multivariate linear stepwise regression model was fitted to the data to predict length of hospitalization, length of operations, and mortality rate. Results: Survivors' mean burn size was 14 ± 15 percent of the total body surface area (range, 5 to 90 percent), with a mean hospitalization time of 22.9 ± 17.1 days and a mean operative time of 127.5 ± 166.8 minutes. The prognostic factors in each of the regression models predicted 40 percent and 55 percent of the variance in length of hospital stay and operative time, respectively. Total body surface area alone explained most of the variance (29 percent and 44 percent, respectively). As a result, the authors created shorter formulas: Length of hospitalization (days) = 18 + [total body surface area]/3; Operative time (minutes) = 55 + 4[total body surface area]. Total body surface area and smoke inhalation were the only statistically significant predictors of death. Every 1 percent increase in total body surface area was associated with a 6 percent increase in mortality risk. The presence of smoke inhalation increased mortality risk by nine-fold. Conclusions: Using objective measurements in burn treatment is of great importance. The formulas presented by the authors explain a considerable percentage of the probability of morbidity in burn victims. The authors suggest that other burn units develop their own statistically supported prediction models.

1 September 2006 in Annals of Plastic Surgery
Verified
Journal Article
Closed access
AZAlon Zahavi
Alon Zahavi
MSMiri Levi Sklair
Miri Levi Sklair
DADean David Ad-El
Dean David Ad-El
Breast reconstruction and augmentation have become a standard surgical treatment worldwide as advancements in medicine and technology enable safer and simpler procedures. A variety of implants is used to mimic a natural breast both in appearance and texture. The most common complication of such procedures is capsular contracture encircling the implant, occurring in approximately 10%. As to date, the contracture is mainly estimated by a physical examination of the breast, which is standardized according to the Baker score. In a cross-sectional study, we compared the clinical assessment of capsular contractures to a radiologic thickness of the capsule, as evaluated by ultrasound (US) and magnetic resonance imaging (MRI). A total of 20 patients, with 27 implants, were evaluated in the study. All patients were examined by a single senior plastic surgeon and divided into 4 groups according to their clinical Baker score estimation. Following, a US imaging of the implant with emphasis on capsular evaluation was performed. The MRI results, recently done prior to the study, were reevaluated in relation to capsular findings. Thirteen breasts had a clinical capsular contraction with a Baker score of I, 8 breasts with a Baker score of II, and 6 breasts with a Baker score of III-IV. The US and MRI images of breasts graded III-IV revealed a thickened capsule (mean of 2.39 mm by US and 2.62 mm by MRI) compared with the capsular imaging of the breasts with the lower clinical Baker scores (mean of 1.14 mm by US and 1.39 mm by MRI). These differences were statistically significant according to the Kruskal-Wallis test, with P values of 0.002 and 0.017, respectively. Both MRI and US studies revealed distinct appearance of the thickened capsule. It seems the capsular thickness as portrayed by US and MRI correlates well with the Baker scoring system and at the same time provides the physician with an objective and consistent evaluation. However, since clinical assessment can be difficult to interpret at times, objective-imaging modalities can be effectively used to assess capsular thickening in women with a clinical suspicion of capsular contraction. A revised classification of capsular contracture, taking into account the imaging of the capsule, is suggested.

29 February 2008 in World Journal of Surgical Oncology
Verified
Journal Article
Open access
PDF file
SCSarit Cohen
Sarit Cohen
DADean David Ad-El
Dean David Ad-El
OBOfer Benjaminov
Ofer Benjaminov
HGHaim Gutman
Haim Gutman
Background: Antecedent trauma has been implicated in the causation of soft tissue tumors. Several criteria have been established to define a cause-and-effect relationship. We postulate possible mechanisms in the genesis of soft tissue tumors following antecedent traumatic injury.Case presentation: We present a 27-year-old woman with a paraspinal desmoid tumor, diagnosed 3-years following a motor vehicle accident. Literature is reviewed.Conclusion: Soft tissue tumors arising at the site of previous trauma may be desmoids, pseudolipomas or rarely, other soft tissue growths. The cause-and-effect issue of desmoid or other soft tissue tumors goes beyond their diagnosis and treatment. Surgeons should be acquainted with this diagnostic entity as it may also involve questions of longer follow-up and compensation and disability privileges.