Julian für allgemeine Orthopädie / Koettnitz

Dr. Julian für allgemeine Orthopädie / Koettnitz

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Research Focus & Metrics

Academic Career Length

5Years (2022-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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1 September 2023 in Clinical Medicine & Research
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JKJulian für allgemeine Orthopädie / Koettnitz
Julian für allgemeine Orthopädie / Koettnitz
JIJan Isbeih
Jan Isbeih
CPChristian D. Peterlein
Christian D. Peterlein
FMFilippo Migliorini
Filippo Migliorini
CGChristian Götze
Christian Götze
Introduction: Knee arthroplasty is exposed to demographic changes as patients age. An analysis of risk factors for surgical treatment decisions in patients over 80 years old is crucial. This study compared perioperative complications between groups of patients undergoing primary knee arthroplasty, under 60 years old and over 80 years old.

8 August 2023 in Archives of orthopaedic and trauma surgery
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JKJulian für allgemeine Orthopädie / Koettnitz
Julian für allgemeine Orthopädie / Koettnitz
JTJara Tigges
Jara Tigges
Filippo MiglioriniFilippo Migliorini
Filippo Migliorini
CPChristian-Dominik Peterlein
Christian-Dominik Peterlein
CGChristian Götze
Christian Götze
Introduction: Total knee arthroplasty (TKA) is a good treatment for end-stage knee osteoarthritis (KOA). Approximately 60% of the patients are females, and 40% are males. This study analyzed pre- and postoperative angle differences in the range of motion (ROM), and the occurrence of complications with traditional posterior stabilization versus kinematic TKA in relation to gender. Methods: Data from 434 patients with primary cemented total knee arthroplasty from 2018 to 2021 were collected. Alpha and beta angles were determined pre- and postsurgery. The ROM was collected pre- and postoperatively and during follow-up. Additionally, perioperative complications, revision rate, and blood transfusion management were investigated. Results: The pre- and postoperative alpha-angle between men and women was significantly different, as was the level of alpha-angle correction between men and women (p = 0.001; p = 0.003). Same-gender differences in pre- to postoperative alpha-angles between traditional and kinematic TKA were shown (women (w): p = 0.001; men (m); p = 0.042). High postoperative alpha angles led to less ROM in traditional TKA for women (p = 0.008). No significant gender differences in ROM, perioperative complications, or revision surgery and transfusion rates were found. Conclusion: Despite high gender differences in pre- and postoperative angles, only female patients with traditional arthroplasty and high postoperative alpha angles showed less ROM in the follow-up. This leads to the assumption that gender-related pre- and postoperative angle differences, and the degree of angle correction, do not influence the ROM or perioperative occurrence of complications. Both designs present safe procedures for both genders with a wide spectrum of axis deformities.

26 August 2022 in Archives of orthopaedic and trauma surgery
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JKJulian für allgemeine Orthopädie / Koettnitz
Julian für allgemeine Orthopädie / Koettnitz
JJJustus Jäcker
Justus Jäcker
FMFilippo Migliorini
Filippo Migliorini
MTMichael Trost
Michael Trost
CPChristian Dominik Peterlein
Christian Dominik Peterlein
CGChristian Götze
Christian Götze
Introduction: Hip arthroplasty is exposed to demographic change as patients age. Analysis of risk factors for surgical treatment decisions in the group of ≥ 80-year-old patients is crucial. Healthcare systems in developed countries are being tested medically and financially by the ageing population. Therefore, this study analysed the perioperative complications of cementless primary hip arthroplasty in octogenarians and compared them with patients aged ≤ 60 years. Methods: A retrospective data analysis of the year 2017 was done in a maximum care hospital of General Orthopaedic Surgery. Patients aged ≥ 80 years or ≤ 60 years with primary cementless hip arthroplasty were included. The outcome of interest was surgery-related and systemic complications, the development of haemoglobin and the incidence of blood transfusion after cementless primary hip arthroplasty in octogenarians during the hospitalisation and the follow-up treatment. Chi-square tests and Fischer's exact test were used for nominal variables. The two-factorial variance analysis-mixed model was used for Hb analyses and the Welch test for group comparison for metric parameters. Results: There was a significantly increased incidence of systemic complications during hospitalisation in the ≥ 80-year-old patients (phi 0.26; Std. Ri − 0.8 (A), 2.2 (B); p = 0.007), as well as a significantly increased rate of blood transfusions (phi 0.403; Std. Ri − 1.3 (A), 3.2 (B); p = < 0.001). No clustered pre-existing conditions in the ≥ 80-year-old patients pointed out a significant association with the incidence of systemic complications. Surgery-related complications showed no significant difference during hospitalisation and follow-up treatment. Conclusion: The study reveals that primary cementless hip prosthesis implantation is a safe procedure without increased incidence of surgery-related complications. Increased attention should be paid to interdisciplinary preoperative optimisation (adjustment of blood pressure, blood transfusions, if necessary, safe exclusion of urinary tract infections) and postoperative care of octogenarians (tight laboratory examinations, geriatric co-attendance).

1 December 2025 in Cells
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Filippo MiglioriniFilippo Migliorini
Filippo Migliorini
Raju VaishyaRaju Vaishya
Raju Vaishya
JKJulian für allgemeine Orthopädie / Koettnitz
Julian für allgemeine Orthopädie / Koettnitz
Madhan JeyaramanMadhan Jeyaraman
Madhan Jeyaraman
LSLuise Schäfer
Luise Schäfer
FSFrancesco Simeone
Francesco Simeone
Focal chondral defects of the knee and ankle remain a challenging clinical condition, particularly in young and active patients, as they often cause pain, mechanical symptoms, and functional limitation without necessarily progressing to osteoarthritis (OA). This narrative review summarises current evidence on non-operative strategies for managing focal chondral lesions in non-arthritic joints, emphasising the role of rehabilitation as the central component of care. A thematic literature search was conducted across major databases for studies published between 2000 and 2025, selecting articles based on clinical relevance. Structured rehabilitation programmes based on load optimisation, neuromuscular retraining, and progressive strengthening represent the foundation of conservative management. Pharmacological agents and intra-articular injectables may provide temporary relief, although the evidence supporting their efficacy remains heterogeneous and primarily short-term. Nutraceuticals and physical modalities show encouraging but inconsistent results, limited by methodological variability and undefined dosing. Overall, conservative treatment should be tailored to the individual patient’s biomechanical and biological profile, integrating rehabilitation with selected adjuncts when appropriate. Future research should focus on developing standardised rehabilitation protocols, identifying predictors of recovery, and clarifying the biological mechanisms that sustain symptom improvement in focal cartilage pathology.

16 August 2023 in BMC Musculoskeletal Disorders
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JKJulian für allgemeine Orthopädie / Koettnitz
Julian für allgemeine Orthopädie / Koettnitz
Filippo MiglioriniFilippo Migliorini
Filippo Migliorini
CPChristian-Dominik Peterlein
Christian-Dominik Peterlein
CGChristian Götze
Christian Götze
Introduction: Total hip (THA) and knee arthroplasty (TKA) are surgical interventions for patients with primary and posttraumatic osteoarthritis. The present clinical investigation compared gender differences in THA and TKA. Methods: Data from 419 patients following primary THA and TKA were collected. The occurrence of systemic and surgery-related complications, the units of blood transfused, and the change in Hb were investigated. Hb was collected preoperatively and at 1, 2, 4 and 7 days postoperatively. Statistical analysis was performed using the software IBM SPSS 28. Results: There was no significant difference in surgery-related and general complications in men between THA and TKA. A significant difference between THA and TKA in systemic complications in women was observed. No significant difference between THA and TKA in related to surgery-related complications was evidenced. In men, no difference in Hb progression was observed. In women, a significant Hb drop was evidenced (p = 0.03). The rate of blood transfusion units in women was significantly greater in TKA than in THA (p = 0.001). No statistically significant difference was observed in men in the rate of transfusion between THA and TKA. Conclusion: Perioperative care should be organized differently for women and men. Furthermore, a differentiation between the procedures for each sex could prevent the occurrence of perioperative complicated courses.

Verified
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IRIsabel Reckermann
Isabel Reckermann
POPatrick Orth
Patrick Orth
CGChristian Götze
Christian Götze
Filippo MiglioriniFilippo Migliorini
Filippo Migliorini
CSCueneyt Sönmez
Cueneyt Sönmez
JKJulian für allgemeine Orthopädie / Koettnitz
Julian für allgemeine Orthopädie / Koettnitz
Background: Total knee arthroplasty (TKA) is a widely performed procedure to alleviate pain and restore function in patients with advanced knee osteoarthritis. Two common implant designs are cruciate-retaining (CR) and posterior-stabilized (PS) knees. Despite extensive research, the superiority of one design over the other remains inconclusive. Methods: A prospective analysis was conducted on 123 patients who underwent total knee arthroplasty (TKA) between June 2022 and June 2023 at a university hospital. Demographic data, mobility, the use of walking aids, pre- and postoperative range of motion and leg axis as well as surgical and systemic complications were collected and compared between CR and PS-TKA. Results: The mean age of the patients was 67.94 ± 10.14 years and 65.9% were women. The time of operation was significantly different between PS- and CR-TKA (PS: 83.31 ± 25.65 min; CR: 95.26 ± 24.61 min; p = 0.011). The pre- to postoperative leg axis after six months was significantly different in both groups (PS: 7.06° ± 4.76°; CR: 6.25° ± 3.13°; p = 0.001). The range of motion (ROM) (PS: 105.19° ± 15.56°; CR: 93.29° ± 15.09°; p = 0.001) as well as the deficit after six months (PS: 23.56° ± 19.73°; CR: 37.57° ± 23.33°; p = 0.003) between patients with PS and CR-TKA were significantly different. Gender (male vs. female PS/CR) and age (75 years PS/CR) differences were shown for the ROM and flexion deficit after six months (p = 0.003; p = 0.005). For age, a significant difference was shown for the quality of life (mean ranks: 75 y: 31.03; p = 0.009) and WOMAC score (mean ranks: 75 y: 61.75; p = 0.001) after six months. Conclusions: This study shows the different outcomes for posterior-stabilized versus cruciate-retaining TKA with regard to time of surgery, range of motion, and flexion deficit after 6 months with PS-TKA yielding better results. The gender analyses revealed similar outcomes after six months between both arthroplasty groups, whereas the age analyses revealed significant differences. The standardized use of PS-TKA for the elderly is recommended.