The frequency of hypodontia in orthodontically treated children, both male and female, and the association between tooth type, the upper or lower arch, the affected side and Angle's classification were studied using interviews, oral, study cast and panoramic radiographic examinations of 212 patients with a mean age of 12 years 7 months. A hypodontia frequency of 11.3 per cent was found for the total sample. This was higher than the incidence of hypodontia reported in other studies of orthodontically treated children. The most frequently missing teeth were the maxillary lateral incisors, and maxillary and mandibular second premolars. The missing teeth were more often absent on the right (54.2 per cent) than on the left (45.8 per cent) side, in both males and females. One tooth was absent in 29.2 per cent of patients, two in 58.5 per cent, but seldom three or more. Orthodontic space closure was the treatment of choice in 87.5 per cent of the subjects.

Objectives This study was done to determine the timing of eruption of permanent teeth by sex and the number of permanent teeth erupted at different ages and to assess its association with malocclusion. Material and Methods The sample for this study consisted of 633 healthy subjects (317 boys and 316 girls) aged between 5.0 and 15.0 years. The subjects were divided into subgroups considering an age interval of 1 year. Results The mean eruption times were lower for girls compared with boys except for the maxillary and mandibular second premolars and second molars, which were found to erupt earlier in boys. All the permanent mandibular teeth, except the second premolars, tended to erupt earlier than their maxillary antagonists in both sexes. The sequence of eruption differs between girls and boys in the maxillary canine and maxillary second premolars. In Class III malocclusion, all the permanent mandibular teeth erupt earlier than their maxillary antagonists. In the entire sample, the correlation between the number of erupted teeth and age was strong (p < .05), but the differences between sexes were not significant. Conclusions It is important to know the normal eruption time of permanent teeth in the population due to diagnosis and better treatment planning in pediatric dentistry and orthodontics.

Objective: To analyze the possible association between hypodontia and epithelial ovarian cancer (EOC), with the special interest in hypodontia pattern. Materials and Methods: One hundred twenty women with EOC treated at the Department of Gynecologic and Breast Oncology at the University Clinical Centre and 120 gynecologically healthy women of the same average age were reviewed for the presence and pattern of hypodontia. Collected data were analyzed for frequency, tooth type, location per jaw and side, number of missing teeth per person, and family history of hypodontia. Results: The results of the study showed prevalence of hypodontia in 19.2% of women with EOC and in 6.7% of women in the control group ( P = .004). The most frequently missing teeth for women with EOC and women in the control group were maxillary second premolars and maxillary lateral incisors, respectively. Unilateral occurrence of hypodontia was more common than bilateral occurrence in women with EOC ( P = .034). Of women with EOC and hypodontia, 21.7% reported a positive family history of hypodontia compared with no report in the control group of women with hypodontia ( P = .150). Conclusions: The results statistically support possible association between EOC and hypodontia. Because hypdontia can be recognized early in life, this finding could possibly help in earlier detection of EOC, resulting in better prognosis and treatment in earlier stages of the disease. Earlier EOC diagnosis and treatment could save many lives.