Breast cancer was the most diagnosed cancer in 2020. Several thousand women continue to die from this disease. A better and earlier diagnosis may be of great importance to improving prognosis, and that is where Artificial Intelligence (AI) could play a major role. This paper surveys different applications of AI in Breast Imaging. First, traditional Machine Learning and Deep Learning methods that can detect the presence of a lesion and classify it into benign/malignant—which could be important to diminish reading time and improve accuracy—are analyzed. Following that, researches in the field of breast cancer risk prediction using mammograms—which may be able to allow screening programs customization both on periodicity and modality—are reviewed. The subsequent section analyzes different applications of augmentation techniques that allow to surpass the lack of labeled data. Finally, still concerning the absence of big datasets with labeled data, the last section studies Self-Supervised learning, where AI models are able to learn a representation of the input by themselves. This review gives a general view of what AI can give in the field of Breast Imaging, discussing not only its potential but also the challenges that still have to be overcome.

Background: The effectiveness of biclustering, simultaneous clustering of rows and columns in a data matrix, was shown in gene expression data analysis. Several researchers recognize its potentialities in other research areas. Nevertheless, the last two decades have witnessed the development of a significant number of biclustering algorithms targeting gene expression data analysis and a lack of consistent studies exploring the capacities of biclustering outside this traditional application domain. Results: This work evaluates the potential use of biclustering in fMRI time series data, targeting the Region × Time dimensions by comparing seven state-in-the-art biclustering and three traditional clustering algorithms on artificial and real data. It further proposes a methodology for biclustering evaluation beyond gene expression data analysis. The results discuss the use of different search strategies in both artificial and real fMRI time series showed the superiority of exhaustive biclustering approaches, obtaining the most homogeneous biclusters. However, their high computational costs are a challenge, and further work is needed for the efficient use of biclustering in fMRI data analysis. Conclusions: This work pinpoints avenues for the use of biclustering in spatio-temporal data analysis, in particular neurosciences applications. The proposed evaluation methodology showed evidence of the effectiveness of biclustering in finding local patterns in fMRI time series data. Further work is needed regarding scalability to promote the application in real scenarios.