Aiming at shortening the design period and improve the design efficiency of the nose shape of high speed trains, a parametric shape optimization method is developed for the design of the nose shape has been proposed in the present paper based on the VMF parametric approach, NURBS curves and discrete control point method. 33 design variables have been utilized to control the nose shape, and totally different shapes could be obtained by varying the values of design variables. Based on the above parametric method, multi-objective particle swarm algorithm, CFD numerical simulation and supported vector machine regression model, multi-objective aerodynamic shape optimization has been performed. Results reveal that the parametric shape design method proposed here could precisely describe the three-dimensional nose shape of high speed trains and could be applied to the concept design and optimization of the nose shape. Besides, the SVM regression model based the multi-points criterion could accurately describe the non-linear relationship between the design variables and objectives, and could be generally utilized in other fields. No matter the simplified model or the real model, the aerodynamic performance of the model after optimization has been greatly improved. Based on the SVR model, the nonlinear relation between the aerodynamic drag and the design variables is obtained, which could provide guidance for the engineering design and optimization.