The emergence of the COVID-19 pandemic and working remotely may decrease the advantages of residing in populated areas. This study aims to test the relationship between remote work and changes in neighborhood satisfaction and to discern the difference according to both the status of remote work and the centrality of areas where people live in the relationships between geographic accessibility to neighborhood facilities and changes in neighborhood satisfaction. By using an ordinal logistic regression, we analyzed data from a questionnaire completed by residents of the 23 wards of Tokyo. Working remotely was found to increase neighborhood satisfaction of people living in a central (OR = 1.31) and a noncentral area (OR = 1.50). Remote workers living in single-family homes were found to be less satisfied with their neighborhoods. Less decrease (or increase) in geographic accessibility to eating facilities was found to be related to increase in neighborhood satisfaction for both remote and nonremote workers regardless of the centrality of areas where they live. The findings suggest that populated areas continue to provide benefits which will improve neighborhood satisfaction even after the start of a pandemic; however, there could be a shift of demand for facilities in central areas to noncentral areas beyond the emergence of the pandemic.