Madalina Gabriela Iliescu

Prof. Dr. Madalina Gabriela Iliescu

Faculty of Medicine, Ovidius University of Constanta, 900527 Constanța, Romania
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Research Focus & Metrics

Academic Career Length

11Years (2016-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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13 July 2023 in Nutrients
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Journal Article
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MPManuela Simona Pop
Manuela Simona Pop
CCCornel Dragos Cheregi
Cornel Dragos Cheregi
GOGelu Onose
Gelu Onose
Constantin MunteanuConstantin Munteanu
Constantin Munteanu
CPCristina Popescu
Cristina Popescu
COCarmen Oprea
Carmen Oprea
This systematic review investigates the potential health and wellness benefits of natural calcium-rich mineral waters. It emphasizes the importance of dietary calcium sourced from natural mineral waters in promoting bone health, maintaining cardiovascular function, aiding in weight management, and enhancing overall well-being. The review process involved the comprehensive analysis of peer-reviewed articles, clinical trials, and experimental studies published within the last decade. Findings reveal that consuming calcium-rich mineral water can contribute significantly to daily calcium intake, particularly for those with lactose intolerance or individuals adhering to plant-based diets. The unique bioavailability of calcium from such waters also appears to enhance absorption, thus potentially offering an advantage over other calcium sources. The potential benefits extend to the cardiovascular system, with some studies indicating a reduction in blood pressure and the prevalence of cardiovascular diseases. Emerging evidence suggests that calcium-rich mineral water might have a role in body weight management, though further research is needed. The review identifies several areas requiring additional research, such as the potential interaction between calcium-rich mineral water and other dietary components, the effects on populations with specific health conditions, and the long-term effects of consumption. In conclusion, natural calcium-rich mineral waters show promise as a readily accessible and bioavailable sources of dietary calcium, potentially beneficial for a broad range of individuals. However, further investigation is required to fully understand its range of health impacts and define optimal intake levels.

25 January 2023 in Metabolites
Verified
Journal Article
Open access
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AUAndreea Bianca Uzun
Andreea Bianca Uzun
MIMadalina Gabriela Iliescu
Madalina Gabriela Iliescu
LSLiliana Elena Stanciu
Liliana Elena Stanciu
EIElena Valentina Ionescu
Elena Valentina Ionescu
Rodica UngurRodica Ungur
Rodica Ungur
DTDoina Ecaterina Tofolean
Doina Ecaterina Tofolean
Intermittent oxygen therapy (IHT), initially used in the hypoxic administration variant, has been shown to be effective in various pathologies studied, from cardiopulmonary to vascular and metabolic pathologies and more. IHT used to prevent and treat various diseases has thus gained more and more attention as the years have passed. The mechanisms underlying the beneficial effects have been investigated at multiple biological levels, from systemic physiological reactions to genomic regulation. In the last decade, a new method of intermittent oxygen therapy has been developed that combines hypoxic and hyperoxic periods. They can be applied both at rest and during physical exercise, hence the specific indications in sports medicine. It has been hypothesized that replacing normoxia with moderate hyperoxia may increase the adaptive response to the intermittent hypoxic stimulus by upregulating reactive oxygen species and hypoxia-inducible genes. This systematic literature review is based on the “Preferred Reporting Items for Systematic Reviews and Meta-Analysis”—“PRISMA”—methodology, the widely internationally accepted method.

24 September 2024 in Toxins
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Journal Article
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Marius Nicolae PopescuMarius Nicolae Popescu
Marius Nicolae Popescu
Cristina PopescuCristina Popescu
Cristina Popescu
CICarmen Andrada Iliescu
Carmen Andrada Iliescu
ARAndreea Racoviță
Andreea Racoviță
MBMihai Berteanu
Mihai Berteanu
Liliana Gabriela PopaLiliana Gabriela Popa
Liliana Gabriela Popa
With the increasing use of Botulinum toxin type A (BoNT-A) injections in the masseter muscles for both medical and aesthetic purposes, there is a constant need to continually enhance the efficacy of these treatments and reduce the risk of potential adverse events. This review provides an in-depth analysis of the masseter muscle’s anatomical structure and essential landmarks and emphasizes the advantages of ultrasound (US) guidance in improving the precision of BoNT-A injections compared to conventional blind methods. The review is supplemented with comprehensive figures, including graphics, clinical images, and ultrasound visuals, to support the discussion. Potential complications such as paradoxical bulging, inadvertent injections into the risorius muscle or parotid gland, facial paralysis, and the risk of bone resorption are examined. Future research should aim at refining injection techniques and assessing the long-term effects of repeated treatments to ensure optimal patient care and safety.

20 February 2024 in Journal of Clinical Medicine
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Journal Article
Open access
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MIMadalina Gabriela Iliescu
Madalina Gabriela Iliescu
LSLiliana-Elena Stanciu
Liliana-Elena Stanciu
AUAndreea Bianca Uzun
Andreea Bianca Uzun
ACAdelina-Elena Cristea
Adelina-Elena Cristea
IMIrina Motoasca
Irina Motoasca
VCViorela Mihaela Ciortea
Viorela Mihaela Ciortea
Background: Cancer rehabilitation represents a series of measures adopted for the recovery of psychological, emotional, social, and financial functioning in the case of cancer patients. The purpose of this study is to identify the main elements of therapeutic management in the field of medical rehabilitation, as well as integrative, complementary medicine and holistic approaches that can be performed on the oncological patient. Methods: This systematic literature review follows the methodology outlined in the “Preferred Reporting Items for Systematic Reviews and Meta-Analysis” (“PRISMA”) statement, which is an internationally recognized and widely accepted standard. Results: Active rehabilitative therapies offer therapeutic options for improving the functioning and quality of life of oncological patients; these therapies comprehensively address both the physical and psychological aspects of the disease. This review also includes the latest novelties and nanotechnologies applied in oncological rehabilitation, for example, drugs (or supplements) inspired by nature. Conclusions: Physical and rehabilitation medicine, mostly using stimulating therapeutic methods, was recently added to the list of contraindications in the management of oncological patients, both as an approach to the pathological concept itself and as an approach to the main clinical consequences and functional aspects of oncological therapies. Integrative, complementary medicine presents an important therapeutic resource in the case of oncological patients. Advanced studies are needed in the future to further ascertain the role of these therapies.

18 February 2022 in Applied Sciences
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Open access
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VCViorela Mihaela Ciortea
Viorela Mihaela Ciortea
IMIrina Motoasca
Irina Motoasca
Ileana Monica BordaIleana Monica Borda
Ileana Monica Borda
Rodica UngurRodica Ungur
Rodica Ungur
CBCosmina Ioana Bondor
Cosmina Ioana Bondor
LILASZLO IRSAY
LASZLO IRSAY
Super Inductive System (SIS) stimulation of spastic limbs by tissue-induced electromagnetic field may have the effect of reducing spasticity and improving functionality in patients with post-stroke spasticity. The aim of the study was to evaluate two different protocols for the application of SIS on upper limb spasticity after stroke. We included 60 patients with post-stroke upper limb spasticity, who were randomized into two groups: the study group, with a 9 min application protocol (1 min for agonist muscles, 8 min for antagonistic muscles); and the control group, with an 8 min protocol applied only to the antagonistic muscles. The duration of therapy was 10 days, and the results were assessed using the Modified Ashworth Scale (MAS) and the Barthel Index. Both the MAS and the Barthel Index improved significantly after 10 days of treatment (p < 0.001), but 30 days after the completion of therapy, there was an attenuation of the effects in both study groups. The study group had a significantly higher percentage of patients with improved MAS after 10 days (p = 0.004) and within 30 days (p < 0.001) than the control group. An SIS protocol applied on both agonist and antagonist muscles has a more pronounced and longer lasting spasticity-reducing and improved functionality effect than its application on only antagonistic muscles.

16 June 2022 in Medicina
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Journal Article
Open access
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Marius Nicolae PopescuMarius Nicolae Popescu
Marius Nicolae Popescu
Cristina PopescuCristina Popescu
Cristina Popescu
MIMadalina Gabriela Iliescu
Madalina Gabriela Iliescu
Mara MihaiMara Mihai
Mara Mihai
Liliana Gabriela PopaLiliana Gabriela Popa
Liliana Gabriela Popa
MBMihai Berteanu
Mihai Berteanu
Psoriasis is a complex immune-mediated inflammatory disorder that generates enormous interest within the scientific communities worldwide, with new therapeutic targets being constantly identified and tested. Despite the numerous topical and systemic medications available for the treatment of psoriasis, alternative therapies are still needed for the optimal management of some patients who present with localized, resistant lesions. Novel insights into the contribution of cutaneous neurogenic inflammation in the pathogenesis of psoriasis have yielded exciting new potential roles of nerve-targeting treatments, namely botulinum toxin type A (BoNT-A), for the management of this disease. This paper aims to review the existing literature on knowledge regarding the potential role of BoNT-A in psoriasis treatment, with a focus on its ability to interfere with the immunopathogenetic aspects of psoriatic disease. Furthermore, in our paper, we are also including the first report of psoriatic lesions remission following local BoNT-A injections that were administered for treating upper limb spasticity, in a patient that concomitantly suffered from psoriasis and post-stroke spasticity.