Linda Popplewell received her BSc in Physiology and Biochemistry in 1988 and PhD in Biological Sciences in 1992, both from the University of Southampton. She worked as a post-doctoral research assistant (PDRA) at the University of Southampton (1993). After some time working as a Clinical Biochemist at Kings College Hospital London, she returned to academia as a senior PDRA at Royal Holloway, University of London in 1998 and was promoted to research officer in 2012. After securing a funded fellowship, she became a lecturer in the Department of Biological Sciences there in 2015, promoted to Reader in Molecular Therapies in 2020. She has been a Professor of Genetic Medicine at the National Horizons Centre since 2022. Her research focuses on the development of therapeutics for rare diseases using antisense oligonucleotides, viral and non-viral gene addition, and genome editing.