Objective: Given the high incidence of sarcopenia among Asians, it is imperative to identify appropriate intervention methods. The International Clinical Practice Guidelines for Sarcopenia, developed by the International Conference on Sarcopenia and Frailty Research (ICFSR) task force, recommends resistance training (RT) as a primary treatment for managing sarcopenia. Inflammatory biomarkers serve as indicators of sarcopenia. However, there is currently insufficient conclusive evidence regarding the effectiveness of RT in modulating inflammatory biomarker levels among Asian participants with sarcopenia.Data sources: Four databases were utilized for this study until October 9, 2023. This study focused on randomized controlled trials (RCTs) that examined the effects of RT on interleukin-6 (IL-6), tumor necrosis factor-α (TNF-α), C-reactive protein (CRP), and interleukin-10 (IL-10) about sarcopenia. This study has been registered in the PROSPERO database (CRD42024501855).Results: The meta-analysis included six studies from Asians involving 278 participants. The results showed a significant decrease in RT for IL-6 (weighted mean difference (WMD) = -0.73, 95% confidence interval (CI) = -1.02 to -0.44; n=5). However, no significant differences were found for TNF-α (WMD = -1.00, 95% CI = -2.47 to 0.46; n=5), CRP (WMD = -0.45, 95% CI = -1.14 to 0.23; n=3), and IL-10 (WMD = 0.13, 95% CI = -3.99 to 4.25; n=2). Subgroup analysis revealed that factors including gender selection, intervention methods, frequency, period, and duration could have a particular effect on the part of inflammatory biomarkers.Conclusion: RT has been shown to reduce part of the level of inflammatory markers, specifically IL-6, in Asian sarcopenia participants. However, other inflammatory factors, such as TNF-α, CRP, and IL-10, did not show significant changes. Further research should confirm the impact of RT on these indicators and explore the potential effects of various factors on different inflammatory markers, such as diet, body composition, and medications.Systematic Review Registration: https://www.crd.york.ac.uk/PROSPERO/display_record.php?RecordID=501855, identifier CRD42024501855.

Music therapy is an effective way to treat the gait disorders caused by Parkinson’s disease. Rhythm music stimulation, therapeutic singing, and therapeutic instrument performance are often used in clinical practice. The mechanisms of music therapy on the gait of patients with Parkinson’s disease include the compensation mechanism of cerebellum recruitment, rhythm entrainment, acceleration of motor learning, stimulation of neural coherence, and increase of cortical activity. All mechanisms work together to complete the intervention of music therapy on patients’ gait and help patients to recover better. In this paper, the effect of music therapy on gait disorders in Parkinson’s disease patients was reviewed, and some suggestions were put forward.

Background: Functional Ankle Instability (FAI) is a pervasive condition that can emerge following inadequate management of lateral ankle sprains. It is hallmarked by chronic joint instability and a subsequent deterioration in physical performance. The modulation of motor patterns through attentional focus is a well-established concept in the realm of motor learning and performance optimization. However, the precise manner in which attentional focus can rehabilitate or refine movement patterns in individuals with FAI remains to be fully elucidated.Objective: The primary aim of this study was to evaluate the impact of attentional focus strategies on the biomechanics of single-leg drop landing movements among individuals with FAI.Methods: Eighteen males with unilateral FAI were recruited. Kinematic and kinetic data were collected using an infrared three-dimensional motion capture system and force plates. Participants performed single-leg drop landing tasks under no focus (baseline), internal focus (IF), and external focus (EF) conditions. Biomechanical characteristics, including joint angles, ground reaction forces, and leg stiffness, were assessed. A 2 × 3 [side (unstable and stable) × focus (baseline, IF, and EF)] Repeated Measures Analysis of Variance (RM-ANOVA) analyzed the effects of attentional focus on biomechanical variables in individuals with FAI.Results: No significant interaction effects were observed in this study. At peak vertical ground reaction force (vGRF), the knee flexion angle was significantly influenced by attentional focus, with a markedly greater angle under EF compared to IF (p < 0.001). Additionally, at peak vGRF, the ankle joint plantarflexion angle was significantly smaller with EF than with IF (p < 0.001). Significant main effects of focus were found for peak vGRF and the time to reach peak vGRF, with higher peak vGRF values observed under baseline and IF conditions compared to EF (p < 0.001). Participants reached peak vGRF more quickly under IF (p < 0.001). Leg Stiffness (k_leg) was significantly higher under IF compared to EF (p = 0.001).Conclusion: IF enhances joint stability in FAI, whereas EF promotes a conservative landing strategy with increased knee flexion, dispersing impact and minimizing joint stress. Integrating these strategies into FAI rehabilitation programs can optimize lower limb biomechanics and reduce the risk of reinjury.

Background: Losing postural control ability and related injuries are of particular concern for elders living in the nursing home (NH). The Otago Exercise Program (OEP) is a multimodal exercise training program initially designed as an individually tailored home exercise for community-dwelling elders, but whether its movement characteristics and exercise intensity meet NH elders’ needs still needs to be clarified. This study aimed to determine the effects of the OEP in enhancing postural control ability among elders in the NH. Methods: A systematic literature search of English language databases (Cochrane Library, PubMed, EMBASE, CINAHL, and Web of Science) and Chinese language databases (China National Knowledge Infrastructure, Wanfang, and Chongqing VIP) until 15 April 2022 were performed by 2 reviewers on searching randomized controlled trial (RCT) and non-RCT. A meta-analysis was performed using Review Manager 5.3 software. Continuous data were expressed as mean difference (MD) with 95% confidence intervals (95% CI). Dichotomous data were presented as risk ratios (RRs) with 95% CI. Study methodological quality was assessed according to the Cochrane Handbook for Systematic Reviews of Interventions for RCTs and Risk Of Bias In Non-randomized Studies-of Interventions for non-RCTs by 3 reviewers. Results: Nine studies with 546 participants were included in this review. Two hundred and sixty-nine participants received OEP, and 277 only had conventional exercise training. Compared to the conventional exercise training group, the NH elders in the OEP group have considerably decreased in fall risk (MD = −0.84; 95% CI = −1.17, −0.51; P < .00001) and positively increased in postural balance (MD = 5.55; 95% CI = 3.60, 7.50; P < .00001), functional mobility in short-distance (MD = −6.39; 95% CI = −8.07, −4.70; P < .00001), lower-limb muscle strength (MD = 4.32; 95% CI = 3.71, 4.93; P < .00001), and health status (risk ratio = 0.35; 95% CI = 0.18, 0.66; P = .001). Conclusions: Current evidence suggests that OEP is practical and feasible in NH. The nursing personnel can receive sufficient support for maintaining and enhancing these elders’ postural control ability, especially during the COVID-19 pandemic.

This study aimed to evaluate the biomechanics of single-leg drop landing in individuals with functional ankle instability (FAI) during cognitive tasks, contrasting these findings with those of healthy controls to provide insights for evidence-based rehabilitation strategies. Fifteen FAI participants, identified using clinical tools, were age- and activity-matched with controls. They performed drop landings with and without a cognitive task, and the data were analyzed using a 2 × 2 mixed ANOVA. At the initial ground contact (IC), the FAI group’s affected side showed a significantly smaller plantarflexion angle than the control group (p = 0.008). With cognitive tasks, this angle increased in the FAI group (p = 0.005). The FAI group also had larger knee flexion at contact (p = 0.002) and greater knee valgus at peak vertical ground reaction force (vGRF) (p = 0.027). They exhibited a higher peak vGRF, shorter time to peak vGRF (T-vGRF), and higher loading rate (LR) (all p < 0.05). No differences were found in other variables (p > 0.05). This study shows that FAI individuals make specific biomechanical adjustments under cognitive tasks, notably increased plantarflexion at IC, suggesting reactive compensations. Despite similar motor control to controls, this may reflect long-term adaptations rather than equal proficiency.

Background: Lateral ankle sprains often progress to functional ankle instability (FAI). Obstacle-crossing could pose greater challenges for individuals with FAI due to significant impairments in ankle kinesthesia and joint position sense. While existing studies have focused on level-ground gait characteristics in FAI, the postural control strategies underlying obstacle-crossing remain unclear, and the impact of obstacle height on these strategies has not been investigated.Purpose: This study is aimed at analyzing the postural control strategies of individuals with FAI during obstacle-crossing at different heights.Methods: Twenty-three male participants [unilateral FAI group (n = 11) and matched controls (n = 12)] were recruited. FAI was identified using the Cumberland Ankle Instability Tool (CAIT score <24). Obstacle heights were set at 0%, 10%, and 20% of individuals’ leg length (LL). Participants completed crossing tasks in randomized order. The individuals with FAI use their FAI-affected limb as the swing leg and controls use the matched limb.Results: Compared to the control group, the FAI group exhibited smaller hip flexion angles (P = 0.008), greater trunk lateral flexion (P = 0.033), and reduced medio-lateral margin of stability (ML_MoS) at landing (P = 0.046). As obstacle height increased, the FAI group showed significant differences in ML_MoS at landing (P < 0.001), with notably lower ML_MoS when the obstacle height was set at 20% LL compared to controls (P = 0.001).Conclusion: Compared to healthy individuals, those with FAI adapt movement patterns through proximal compensation strategies, characterized by compensatory trunk lateral flexion. Increased obstacle height exacerbates instability during landing, particularly at higher heights, where individuals with FAI demonstrate significantly diminished lateral stability. These findings emphasize the critical influence of FAI on balance control and adaptive postural control strategies during obstacle-crossing.