With as many as 4 million passenger journeys within the London Underground system every weekday, the advertisement spaces across the stations hold considerable potential. However, the planning of specific advertisements across time and space is difficult to optimize as little is known about passers-by. Therefore, in order to generate detailed and quantifiable spatio-temporal information which is particular to each station area, we have explored local social media data. This research demonstrates how local interests can be mined from geotagged Tweets by using Latent Dirichlet Allocation, an unsupervised topic modelling method. The relative popularity of each of the key topics is then explored spatially and temporally between the station areas. Overall, this research demonstrates the value of using Geographical Information System and text-mining techniques to generate valuable spatio-temporal information on popular interests from Twitter data.