Martina Nesti

Dr. Martina Nesti

orcid

Research Focus & Metrics

Academic Career Length

13Years (2014-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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19 July 2021 in EP Europace
Verified
Journal Article
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RGRodrigue Garcia
Rodrigue Garcia
VWVictor Waldmann
Victor Waldmann
PVPhilippe Vanduynhoven
Philippe Vanduynhoven
Martina NestiMartina Nesti
Martina Nesti
MFMarcio J. O. Figueiredo
Marcio J. O. Figueiredo
DDDavid Duncker
David Duncker
Catheter ablation for atrial fibrillation (AF) has become one of the most common procedures in the electrophysiology lab with rapidly increasing volumes. Peri-procedural anaesthesia for AF ablation varies between centres, from general anaesthesia to deep or conscious sedation. The aim of this survey was to assess current sedation practices for AF ablation worldwide and its evolution over the last decade. Centres regularly performing AF ablation responded to an online survey. A total of 297 centres participated in the survey. Overall, the median (interquartile range) number of AF ablation procedures increased from 91 (43–200) to 200 (74–350) per year (P < 0.001) between 2010 and 2019. The proportion of cryoablation also increased from 17.0% to 33.2% (P < 0.001). In 2019, the most used sedation technique was general anaesthesia (40.5%), followed by conscious sedation (32.0%) and deep sedation (27.5%). Between 2010 and 2019, the proportion of procedures performed under general anaesthesia (+4.4%; P = 0.02) and deep sedation (+4.8%; P < 0.01) increased, whereas the use of conscious sedation decreased (−9.2%; P < 0.001). The most commonly used hypnotic drugs were propofol and midazolam, whereas the most commonly used opioid drugs were remifentanyl and fentanyl. This worldwide survey shows that the number of AF ablation procedures has more than doubled over the last decade and general anaesthesia remains most commonly used. Studies comparing outcomes between different sedation strategies are needed to guide optimal decision-making.

13 September 2023 in Journal of Clinical Medicine
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Journal Article
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FLFabiana Lucà
Fabiana Lucà
OFOliva Fabrizio
Oliva Fabrizio
MAMaurizio Giuseppe ABRIGNANI
Maurizio Giuseppe ABRIGNANI
SFStefania Angela Di Fusco
Stefania Angela Di Fusco
IPIris Parrini
Iris Parrini
MGMichele Massimo Gulizia
Michele Massimo Gulizia
It is well established that direct oral anticoagulants (DOACs) are the cornerstone of anticoagulant strategy in atrial fibrillation (AF) and venous thromboembolism (VTE) and should be preferred over vitamin K antagonists (VKAs) since they are superior or non-inferior to VKAs in reducing thromboembolic risk and are associated with a lower risk of intracranial hemorrhage (IH). In addition, many factors, such as fewer pharmacokinetic interactions and less need for monitoring, contribute to the favor of this therapeutic strategy. Although DOACs represent a more suitable option, several issues should be considered in clinical practice, including drug–drug interactions (DDIs), switching to other antithrombotic therapies, preprocedural and postprocedural periods, and the use in patients with chronic renal and liver failure and in those with cancer. Furthermore, adherence to DOACs appears to remain suboptimal. This narrative review aims to provide a practical guide for DOAC prescription and address challenging scenarios.

10 January 2024 in European Journal of Preventive Cardiology
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Journal Article
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Sciarra LuigiSciarra Luigi
Sciarra Luigi
PGPaolo Golia
Paolo Golia
ASAntonio Scarà
Antonio Scarà
ARAntonio Gianluca Robles
Antonio Gianluca Robles
MMMelissa De Maio
Melissa De Maio
ECElena Cavarretta
Elena Cavarretta
In athletes with right bundle branch block (RBBB) morphology non-sustained ventricular arrhythmias (VAs), the presence of a non-ischaemic left ventricular scar (NLVS) may be highly suspected if one or more of the following electrocardiogram (ECG) characteristics are present at the 12-lead resting ECG: low QRS voltages in limb leads, negative T waves in inferior leads, negative T waves in limb leads I–aVL, negative T waves in precordial leads V4–V6, presence of left posterior fascicular block, presence of pathologic Q waves, and poor R-wave progression in right precordial leads. This score should be externally validated in a larger population of athletes with VAs.

27 July 2023 in EP Europace
Verified
Journal Article
Open access
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RARaquel Adeliño
Raquel Adeliño
KMKatarzyna Małaczyńska-Rajpold
Katarzyna Małaczyńska-Rajpold
LPLaura Perrotta
Laura Perrotta
MMMartin Manninger
Martin Manninger
PVPhilippe Vanduynhoven
Philippe Vanduynhoven
JCJulian K R Chun
Julian K R Chun
Aims: Electrophysiology (EP) is a growing field in cardiology, with an increasing involvement of young people. Nevertheless, concerns about radiation exposure and its impact on reproduction and pregnancy may discourage the choice of an EP career. The study is aimed at investigating the level of awareness and main sources of concern about the effects of radiation on reproductive potential and pregnancy, exploring the safety measures adopted in different EP labs, and verifying the adherence to the current guidelines. Methods and results: An online survey was conducted using the European Heart Rhythm Association (EHRA) infrastructure from April to June 2022. A total of 252 EP personnel (42% women) participated, from 50 countries and different professional roles. Most participants expressed concerns regarding the effects of radiation on reproductive capacity (67.1%) and offspring diseases (68.2%). Only 37.9% of participants were aware of the EHRA 2017 consensus document about occupational radiation exposure. Most participants (80.9%) considered that occupational radiation during pregnancy is not safe. EP female staff were not allowed to work in the EP lab during pregnancy in 48.1% of cases. Zero-fluoroscopy was the preferred choice to continue working in the EP lab during pregnancy. Conclusion: EP staff, including both men and women, have concerns about the effects of radiation on reproductive capacity. Despite the recommendations issued by international bodies, implementation of the policies regarding pregnancy and occupational radiation exposure is heterogeneous. Zero-fluoroscopy is the preferred approach to ensure safety during pregnancy in the EP lab.

11 August 2022 in Journal of Clinical Medicine
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Journal Article
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ARAntonio Gianluca Robles
Antonio Gianluca Robles
ZPZefferino Palamà
Zefferino Palamà
Martina NestiMartina Nesti
Martina Nesti
RTRoberto michele Tunzi
Roberto michele Tunzi
PDPietro Delise
Pietro Delise
Sciarra LuigiSciarra Luigi
Sciarra Luigi
Sports are a double-edged sword. On the one hand, cardiovascular benefits from sports activity are well-known, and on the other hand, sports may increase the risk of sudden cardiac death (SCD) in subjects with known or unknown cardiovascular diseases. SCD is rare but has a very strong emotional issue. There are many examples involving famous professional athletes, but this is only scratching the surface of a widespread phenomenon that also involves amateur athletes. The importance of safely performing physical activity appears clear in both professional and amateur athletes. In particular, the former undergo a pre-participation screening for SCD primary prevention with different recommendations in each country. On the other hand, a medical examination is not mandatory for non-professional athletes and, therefore, for people who practice sports as an amateur. Widespread distribution of automatic external defibrillators and people trained for cardiopulmonary resuscitation are necessary to promote secondary prevention of SCD. We briefly report a case series of athletes with aborted SCD during sports activity in order to underline and discuss in this review the previously highlighted issues.

7 August 2024 in Journal of Clinical Medicine
Verified
Journal Article
Open access
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FLFabiana Lucà
Fabiana Lucà
MAMaurizio Giuseppe ABRIGNANI
Maurizio Giuseppe ABRIGNANI
OFOliva Fabrizio
Oliva Fabrizio
MCMaria Laura Canale
Maria Laura Canale
IPIris Parrini
Iris Parrini
MGMichele Massimo Gulizia
Michele Massimo Gulizia
Atrial fibrillation (AF) represents the most common sustained arrhythmia necessitating dual focus: acute complication management and sustained longitudinal oversight to modulate disease progression and ensure comprehensive patient care over time. AF is a multifaceted disorder; due to such a great number of potential exacerbating conditions, a multidisciplinary team (MDT) should manage AF patients by cooperating with a cardiologist. Effective management of AF patients necessitates the implementation of a well-coordinated and tailored care pathway aimed at delivering optimized treatment through collaboration among various healthcare professionals. Management of AF should be carefully evaluated and mutually agreed upon in consultation with healthcare providers. It is crucial to recognize that treatment may evolve due to the emergence of new risk factors, symptoms, disease progression, and advancements in treatment modalities. In the context of multidisciplinary AF teams, a coordinated approach involves assembling a diverse team tailored to meet individual patients’ unique needs based on local services’ availability.