Aortobronchial fistula is a rare cause of repeated hemoptysis and a potentially fatal condition if left untreated. We present the case of a 40-year-old man with repeated hemoptysis, excessive cough, and epistaxis ongoing for several days after SARS-CoV-2 pneumonia diagnosis. The patient had a history of patch aortoplasty for aortic coarctation and aortic valve replacement with a mechanical valve for aortic insufficiency due to bicuspid aortic valve at the age of 24. Computed tomography scan performed at presentation revealed a severely dilated ascending aorta, a thoracic aorta pseudoaneurysm at the site of the former coarctation, an aortobronchial fistula suggested by the thickened left lower lobe apical segmental bronchus in contact with the pseudoaneurysm and signs of alveolar hemorrhage in the respective segment. The patient was treated with thoracic endovascular aneurysm repair (TEVAR) after prior hemi-aortic arch debranching and transposition of the left common carotid artery and subclavian artery through a closed-chest surgical approach. Our case report together with a systematic review of the literature highlight the importance of both considering an aortobronchial fistula in the differential diagnosis of hemoptysis in patients with prior history of thoracic aorta surgical intervention, regardless of associated pathology, and of taking into account endovascular and hybrid techniques as an alternative to open surgical repair, which carries a high risk of morbidity and mortality.

Cervical intraepithelial neoplasia (CIN) is a multifactorial pathology mainly determined by persistent infection with high-risk human papillomavirus (HPV) genotypes and modulated by both immunological and psychological factors. This mixed bibliometric and empirical study integrates psychoneuroimmunological concepts with clinical data from a cohort of 150 patients (aged 18–55 years) from northern Romania. Seventy percent tested positive for high-risk HPV by self-sampling and all completed the PHQ-9 and GAD-7 scales that were subsequently assessed. Symptoms of depression and anxiety were prevalent, with anxiety being reported by 43% of participants who performed self-sampling at home.Fifty women with cytologically diagnosed HSIL underwent a comparative evaluation using both, classical colposcopy and the artificial intelligence-assisted EVA system (MobileODT, Israel). Artificial intelligence-based colposcopy demonstrated higher sensitivity (92% versus 82%) and higher diagnostic concordance (88%) with histopathological confirmation, suggesting superior accuracy and clinical feasibility.These results support the integration of psychoneuroimmunological and artificial intelligence-assisted diagnostic parameters into cervical cancer prevention frameworks, highlighting the importance through which artificial intelligence could complement neoplasia prevention, addressing psychological profile and biological markers to improve personalised risk stratification.

Health education is an essential topic for the contemporary society because it focuses on delivering information to enhance and sustain community health. This type of education covers issues of broad interest, such as disease prevention, promoting a healthy lifestyle, the significance of nutrition and exercise and stress reduction. Health education aims to raise awareness and build the necessary skills for a healthy behavior. This article aims to develop the concept of "health education" and highlight its importance for the society and the economy by reviewing the literature. We believe that there is a significant connection between health education, population health and the economy as the formation of healthy adults emerges from a well-balanced childhood, which is beneficial to long-term economic development.

Background and Objectives: Metastases are the most common tumors of the spine. As an important increase in the annual incidence of spinal metastases (SM) has been observed in the last decade, the aim of this study was to describe the epidemiology and histopathological types of SM surgically treated in the neurosurgery clinics of a regional hospital in North-Eastern Romania over a period of 5 years, in order to define a certain tumor profile that would benefit from an early screening. Materials and Methods: We retrospectively evaluated 115 adult patients, searching for demographic data (gender and age of the patients), primary tumor characteristics (location and histological type), topography and histopathological type of the spinal metastasis, and the time interval between the diagnosis of the primary tumor and the surgery for the spinal metastasis. Results: The patients were elderly (average age = 58.96 years), with a male predominance (67.82%). Main location of SM was in thoracic region (44.34%), with multiple vertebral metastases in 30.43% patients. Only 33.04% of the patients had a known cancer at the time of admission. Primary tumor was located mainly in lung (47.82%), gastrointestinal tract (15.65%), breast (11.30%), prostate (10.43%) and kidney (9.56%). SM from lung cancer mostly expressed squamous cell carcinoma (19.13%), and those from the digestive system mostly exhibited a moderately/poor colorectal adenocarcinoma (8.69%). Conclusions: Our data suggest the need for close surveillance of patients diagnosed with lung cancer and colorectal cancer because these malignancies most frequently develop spinal metastases. Smoking prevention actions and screening programs for the detection and removal of precancerous colorectal lesions must be developed and expanded.

Health system resilience has emerged as a critical competency in health management education, yet pedagogical frameworks for teaching resilience through structured comparative analysis remain underdeveloped. This study addresses this gap by developing and demonstrating a replicable educational framework that integrates organizational resilience theory with comparative health policy analysis, specifically designed for graduate-level health management, public health, and public administration curricula. The study makes three distinct contributions to international health management education. Conceptually, it provides a unified analytical framework integrating macro-level policy analysis with meso-level institutional outcomes, enabling multi-scalar resilience teaching. Methodologically, it models rigorous secondary analysis research design accessible to graduate students in resource-constrained environments, supporting research literacy development. The pedagogical applications are immediate and concrete: the framework can be integrated directly into health systems governance courses, policy analysis modules, and crisis management curricula; the comparative findings provide structured case teaching material suitable for problem-based learning exercises; and the methodological transparency supports student-led comparative research projects. By explicitly connecting theoretical constructs, empirical evidence, and pedagogical implementation, the study advances evidence-informed curriculum development in health management education and provides a model for translating health systems research into teaching practice.

Cervical cancer remains a major global health concern, causing substantial morbidity and mortality, particularly in low- and middle-income countries. Beyond its physical burden, patients frequently experience significant psychological distress, including anxiety and depression, which can adversely affect treatment adherence, daily functioning, and overall quality of life. Emerging evidence highlights the intricate relationships between psychological well-being, nutritional status, and oxidative stress in this population. Malnutrition and cancer cachexia may exacerbate fatigue, cognitive dysfunction, and emotional vulnerability, while oxidative stress contributes both to disease progression and neuropsychological disturbances. This narrative review synthesizes current research on anxiety and depression in cervical cancer patients, emphasizing how impaired nutritional status and elevated oxidative stress are associated with increased psychological burden. Understanding these interconnections is essential for developing comprehensive, multidisciplinary interventions that address both somatic and emotional health, optimize patient outcomes, and improve quality of life.