Endoscopic ultrasound (EUS) and endoscopic retrograde cholangiopancreatography (ERCP) are both crucial for the endoscopic management of biliopancreatic diseases: the combination of their diagnostic and therapeutic potential is useful in many clinical scenarios, such as indeterminate biliary stenosis, biliary stones, chronic pancreatitis and biliary and pancreatic malignancies. This natural and evident convergence between EUS and ERCP, which by 2006 we were calling the “Endoscopic ultrasonography retrograde colangiopancreatography (EURCP) concept”, has become a hot topic in the last years, together with the implementation of the therapeutic possibilities of EUS (from EUS-guided necrosectomy to gastro-entero anastomoses) and with the return of ERCP to its original diagnostic purpose thanks to ancillary techniques (extraductal ultrasound (EDUS), intraductal ultrasound (IDUS), cholangiopancreatoscopy with biopsies and probe-based confocal laser endomicroscopy (pCLE)). In this literary review, we retraced the recent history of EUS and ERCP, reported examples of the clinical applicability of the EURCP concept and explored the option of performing the two procedures in only one endoscopic session, with its positive implications for the patient, the endoscopist and the health care system. In the last few years, we also evaluated the possibility of combining EUS and ERCP into a single endoscopic instrument in a single step, but certain obstacles surrounding this approach remain.

Salivary gland enlargement following iodine-containing contrast media (ICCM), also known as iodide mumps (IM), is a rare condition characterized by swelling of submandibular glands with complete restitutio ad integrum. It manifests itself without pain, fever, dyspnea, rapid heart rate or low blood pressure. The pathogenesis is unknown, it may be an idiosyncratic reaction or toxic due to deposition of iodide in the salivary glands. IM is a condition more frequent in end stage renal disease because of iodine excretion by kidneys but it can also occur in patients without end stage renal disease. In this study, we described a 71-year-old patient with liver cirrhosis due to hepatitis B virus with normal renal function that after administration of ICCM developed IM.

Text A 42-years-old woman, due to sideropenic anemia and melena, underwent an esophagogastroduodenoscopy in which was found a large peduncolated polyp with the base in the duodenal bulb, whose head, measuring approximately 45 mm, could not be pull in the antrum for a safer polypectomy due. An Endoscopic VLS-assisted polypectomy was performed in which the surgeon press on the stomach and duodenal bulb under endoscopist instruction to push the polyp’s head in the antrum. Then a standard piecemeal hot snare polypectomy was performed. The pathologist analyses reveal an hamartomatous polyp without dysplasia and the patient underwent Peutz–Jeghers syndrome genetic test. Article published online: 14 April 2023 © 2023. European Society of Gastrointestinal Endoscopy. All rights reserved. Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, Germany

Text We present a case of a 57-years old woman with a FNB diagnosis of insulinoma in the body of the pancreas with a size of 13 mm; during the diagnostic work up in MRI a pancreas divisum was discovered. Due to the small size of the lesion, a laparoscopic enucleation was planned. Before surgery she was referred for tattoing of the lesion in EUS to improve lesion’s localization. In the same session a prophylactic pancreatic duct stent was positioned to reduce the risk of duct damage, acute pancreatitis and the development of fistul [1]. Article published online: 14 April 2023 © 2023. European Society of Gastrointestinal Endoscopy. All rights reserved. Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, Germany