Background: Childhood dyslipidemia is an important risk factor for developing cardiovascular disease in adulthood. Our study aimed to investigate a possible correlation between nutritional, lifestyle, behavioral and socioeconomic factors and serum lipid levels in children with dyslipidemia. Methods: In this retrospective, observational study, in 31 children with dyslipidemia, aged 3–14 years, dietary habits, physical activity, hours watching television or playing video games, family’s socioeconomic status, weight of children and parents, and duration of breastfeeding were recorded. The children’s adherence to the Mediterranean diet was also evaluated by KidMed index. Statistical analysis was performed using SPSS.22. Results: Children with increased physical activity had lower triglyceride levels, compared to those with lower physical activity (p = 0.001). Children who consumed only one meal per day, had increased levels of total cholesterol (p = 0.01), LDL-cholesterol (p = 0.01), ApoB (p = 0.001) and lipoprotein (a) (p = 0.018), compared to those who consumed more than 3 meals per day (p < 0.05). Children who were breastfed less than 6 months had significantly increased LDL-C levels (p = 0.022), compared to children who were breastfed more than 6 months. All other parameters investigated did not differ significantly. Conclusions: This study showed association between lipid profile of children with dyslipidemia and specific nutritional and socioeconomic factors, such as increased physical activity, increased meals consumption during the day, and exclusive breastfeeding for more than 6 months. Nevertheless, further research is needed, in order to confirm these findings.

Vitamin supplements are over-the-counter medications consumed by the majority of adults. Given that many supplements may be ineffective and/or associated with adverse events, compliance of the registered trials to the European Medicines Agency (EMA) rule for prompt reporting of the results is of crucial importance for consumers’ health. The present retrospective study was designed to evaluate compliance with the European Union (EU) requirement to post the trial results to the EU Clinical Trials Database (EudraCT) and assess the trial characteristics associated with this compliance. Three independent researchers searched the EudraCT for completed trials on vitamin supplements performed on humans. A total of 144 completed trials involving 40,464 participants fulfilled the inclusion criteria. For 45.7% of these, results were due. Trials funded by the industry had approximately quadruple chances of being published, adjusting for their design, masking, comparator, and participant age group. Moreover, trials testing vitamin supplement safety are more likely to report their findings as compared to vitamin efficacy. Many vitamin supplementation trials registered in the EudraCT failed to report their results and adhere to the EMA regulations. Stricter regulations should be imposed concerning trial results reporting to increase transparency and public trust.