Aline Pioli Silva

Mrs. Aline Pioli Silva

orcid

Research Focus & Metrics

Academic Career Length

5Years (2022-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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9 August 2022 in Bioengineering
Verified
Journal Article
Open access
PDF file
JBJuliana O. Bahú
Juliana O. Bahú
Lucas Rannier Melo de AndradeLucas Rannier Melo de Andrade
Lucas Rannier Melo de Andrade
RBRaquel de Melo Barbosa
Raquel de Melo Barbosa
SCSara Crivellin
Sara Crivellin
ASAline Pioli Silva
Aline Pioli Silva
Eliana B. SoutoEliana B. Souto
Eliana B. Souto
Hydrogels are a great ally in the pharmaceutical and biomedical areas. They have a three-dimensional polymeric structure that allows the swelling of aqueous fluids, acting as an absorbent, or encapsulating bioactive agents for controlled drug release. Interestingly, plants are a source of biogels, specifically polysaccharides, composed of sugar monomers. The crosslinking of these polymeric chains forms an architecture similar to the extracellular matrix, enhancing the biocompatibility of such materials. Moreover, the rich hydroxyl monomers promote a hydrophilic behavior for these plant-derived polysaccharide gels, enabling their biodegradability and antimicrobial effects. From an economic point of view, such biogels help the circular economy, as a green material can be obtained with a low cost of production. As regards the bio aspect, it is astonishingly attractive since the raw materials (polysaccharides from plants-cellulose, hemicelluloses, lignin, inulin, pectin, starch, guar, and cashew gums, etc.) might be produced sustainably. Such properties make viable the applications of these biogels in contact with the human body, especially incorporating drugs for controlled release. In this context, this review describes some sources of plant-derived polysaccharide gels, their biological function, main methods for extraction, remarkable applications, and properties in the health field.

25 August 2023 in Journal of Traditional and Complementary Medicine
Verified
Journal Article
Open access
ASAna L.G. de Brito Siqueira
Ana L.G. de Brito Siqueira
PCPedro V.V. Cremasco
Pedro V.V. Cremasco
JBJuliana O. Bahú
Juliana O. Bahú
ASAline Pioli Silva
Aline Pioli Silva
LALucas R. Melo de Andrade
Lucas R. Melo de Andrade
Eliana B. SoutoEliana B. Souto
Eliana B. Souto
Scientific evidence exists about the association between neurological diseases (i.e., Parkinson's disease, Alzheimer's disease, amyotrophic lateral sclerosis (ALS), multiple sclerosis, depression, and memory loss) and oxidative damage. The increasing worldwide incidence of such diseases is attracting the attention of researchers to find palliative medications to reduce the symptoms and promote quality of life, in particular, in developing countries, e.g., South America and Africa. Among potential alternatives, extracts of Cannabis Sativa L. are suitable for people who have neurological disorders, spasticity, and pain, nausea, resulting from diseases such as cancer and arthritis. In this review, we discuss the latest developments in the use of Cannabis, its subtypes and constituents, extraction methods, and relevant pharmacological effects. Biomedical applications, marketed products, and prospects for the worldwide use of Cannabis Sativa L. extracts are also discussed, providing the bibliometric maps of scientific literature published in representative countries from South America (i.e., Brazil) and Africa (i.e., South Africa). A lack of evidence on the effectiveness and safety of Cannabis, besides the concerns about addiction and other adverse events, has led many countries to act with caution before changing Cannabis-related regulations. Recent findings are expected to increase the social acceptance of Cannabis, while new technologies seem to boost the global cannabis market because the benefits of (−)-trans-delta-9-tetrahydrocannabinol (Δ9-THC) and cannabidiol (CBD) use have been proven in several studies in addition to the potential to general new employment.

20 April 2023 in Energies
Verified
Journal Article
Open access
PDF file
ASAline Pioli Silva
Aline Pioli Silva
JBJuliana Otavia Bahú
Juliana Otavia Bahú
RSRenato Soccol
Renato Soccol
LRLeonardo Rodriguez-Urrego
Leonardo Rodriguez-Urrego
WFWilliam Stive Fajardo-Moreno
William Stive Fajardo-Moreno
VCViktor Oswaldo Cárdenas Concha
Viktor Oswaldo Cárdenas Concha
Naphtha is an important distillation product of crude oil, and is used as a raw material for first-generation products such as ethylene, propylene, gasoline, xylene (BTX), and others. However, due to the different sources of crude oil, differences in naphtha composition impact the quality of conversion processes. Parameters such as pressure, charge flow, and temperature need to be adjusted for conversion efficiency. This work aims to compare naphtha samples from different origins, through the analysis of distillation curve (ASTM D86), density (ASTM D4052), total sulfur (ASTM D4294), and n-paraffins, iso-paraffins, olefins, naphthene, and aromatics (PIONA, ASTM D5134). Among these parameters evaluated in naphtha, the ones that showed the greatest correlation with the type of oil and its origin was the amount of total sulfur, number of aromatics, and paraffins. The three imported evaluated naphtha presented values greater than 200 mg/kg of total sulfur, aromatics above 9%w, and paraffins (P + I) below 76%w, while the national naphtha presented sulfur contents of at most 141 mg/kg, aromatics below 7%w, and paraffins (P + I) above 78%w. Finally, the study of this type of hydrocarbon enables the understanding of the needs of Latin American refineries and the world in relation to its treatment. National petrochemical companies have more difficulty in processing this product, causing an increase in naphtha importation by 108.51% from 2020/2021 in Brazil. Given this scenario, the Brazilian government should invest more in its petrochemical plants to reduce these imports, which, in the long term, would have a positive impact on the quality and value of naphtha byproducts.