Vaccine hesitancy represents a global public health challenge that can diminish the effectiveness of vaccination programs. Research indicates that various sociodemographic and socioeconomic factors, along with health literacy, predict vaccine hesitancy. In this study, we analyzed data from a Slovenian health literacy survey that included 3360 adult participants. We examined the effects of sociodemographic (gender and age) and socioeconomic factors (education, economic deprivation, and self-assessed socioeconomic status), as well as different dimensions of health literacy (general, communicative, and navigational), on vaccine hesitancy. The results show that age, education, and economic deprivation are statistically significant predictors of vaccine hesitancy; younger individuals, those with lower education levels, and those experiencing greater economic deprivation express increased vaccine hesitancy. Higher levels of general and communicative health literacy are associated with lower vaccine hesitancy, while navigational health literacy was not found to be a statistically significant predictor of vaccine hesitancy.

Trust in science and scientists, satisfaction with the national government, and endorsement of conspiracy theories are important factors in the decision to be vaccinated. In this study, we investigated whether there are different profiles of individuals depending on the above factors and whether they differ in their sociodemographic composition. We used data from Round 10 of the European Social Survey for Slovenia, employing a nationally representative sample of 1252 participants. Based on latent profile analysis, three distinct profiles emerged: Profile 1 expressed moderate trust in science, satisfaction with government, and high endorsement of conspiracies; Profile 2 expressed low trust and satisfaction and moderate endorsement of conspiracies; Profile 3 expressed high trust and satisfaction and low beliefs in conspiracy theories. In addition, Profile 3 expressed the strongest support for vaccination and Profile 2 the lowest. Our results suggest that distrust, dissatisfaction, and the presence of conspiracy theories are the “perfect storm” for vaccination rejection. In contrast, despite conspiracy theories, a certain level of trust and satisfaction may reduce vaccination rejection.

Predictors of COVID-19 (coronavirus) vaccination have been extensively researched; however, the contextual factors contributing to understanding vaccination intention remain largely unexplored. The present study aimed to investigate the moderating role of economic development (Gross domestic product - GDP per capita), economic inequality (Gini index), the perceived corruption index and Hofstede’s measurements of cultural values—index of individualism/collectivism and power distance index—in the relationship between determinants of satisfaction with the healthcare system, trust in political institutions, conspiracy beliefs and COVID-19 vaccination intention. A multilevel modelling approach was employed on a sample of approximately 51 000 individuals nested within 26 countries. Data were drawn from the European Social Survey Round 10. The model examined the effect of individual- and country-level predictors and their interaction on vaccination intention. Satisfaction with the healthcare system had a stronger positive effect on intention to get vaccinated in countries with lower perceived corruption and more individualistic countries. Trust in political institutions had a stronger positive effect on vaccination intention in countries with higher economic development and lower perceived corruption, while a negative effect of conspiracy beliefs on vaccination intention was stronger in countries with lower economic development, higher perceived corruption and a more collectivistic cultural orientation. Our findings highlight the importance of considering individual and contextual factors when addressing vaccination intention.

Introduction: Health literacy is an important predictor of health behavior and self-rated health, playing a crucial role in shaping public health outcomes. Valid and reliable health literacy assessments are essential for effectively tailoring health interventions, particularly in different cultural contexts. Several questionnaires have been developed to measure health literacy, including the widely used 47-item Health Literacy Questionnaire and its shorter versions. However, the validity of these shorter and more time efficient HLS-EU versions, such as the 16-item HLS-EU-Q16, has been less extensively researched in different age subgroups. Given Slovenia’s aging population and the differences in health literacy between adults and older adults, it is important to assess whether the HLS-EU-Q16 performs reliably across these groups. Therefore, the present study aimed to examine the validity and reliability of the 16-item health literacy questionnaire (HLS-EU-Q16) in Slovenia across two age groups: adults and older adults.Methods: We analyzed representative Slovenian sample data from the Health Literacy of Adults study. The sample included 2,327 adults aged 23–64 years (53.7% women) and 876 older adults aged 65–99 years (55.7% women).Results: Construct validity revealed a modified three-factor structure of the HLS-EU-Q16 among adults, reflecting a broader conceptualization of health literacy that encompasses overlapping domains of health promotion, disease prevention, and health care. In contrast, a two-factor structure emerged among older adults, indicating a more consolidated approach where these domains are perceived as part of an integrated health management strategy. This suggests that adults may conceptualize health literacy across multiple, yet interconnected dimensions, while older adults approach it more holistically. Convergent validity, reliability, concurrent-predictive, concurrent, and discriminant validity results were satisfactory for both age groups. Predictive validity, however, provided somewhat inadequate results, as the tool poorly predicted certain health behaviors, such as smoking, alcohol consumption, and physical activity, in both age groups.Conclusion: Overall, the HLS-EU-Q16 demonstrated adequate validity and reliability among both adults and older adults, indicating that it is an appropriate instrument for assessing health literacy in Slovenia.

Vaccine hesitancy and its determinants have been previously widely researched. Vaccine hesitancy has been defined as a continuum of attitudes, ranging from accepting vaccines with doubts to rejecting them. The present study aims to explore the heterogeneity of a childhood-vaccine-hesitant group by using a person-oriented approach–latent profile analysis. A non-representative cross-sectional sample of vaccine-hesitant Slovenians (N = 421, M_age = 35.21, 82.9% women) was used to identify differences based on their reliance on personal research (“self” researching instead of relying on science), overconfidence in knowledge, endorsement of conspiracy theories, complementary and alternative medicine, and trust in the healthcare system. The analysis revealed three profiles of vaccine-hesitant individuals. The most hesitant profile—vaccine rejecting—expressed the greatest reliance on personal research, expressed the highest endorsement of conspiracy theories and complementary and alternative medicine, showed moderate overconfidence in their knowledge, and expressed the highest levels of distrust in the healthcare system. We further found differences in sociodemographic structure and that the identified profiles differed in their attitudes regarding MMR, HPV, and Seasonal Influenza vaccinations. The present study demonstrates the heterogeneity of the vaccine-hesitant community and offers insights into some of the traits, which are crucial for designing pro-vaccine campaigns.