Andrew Wallace Kirkpatrick

Dr. Andrew Wallace Kirkpatrick

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Research Focus & Metrics

Academic Career Length

21Years (2006-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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15 May 2013 in Intensive Care Medicine
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Journal Article
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TSThe Pediatric Guidelines Sub-Committee for the World Society of the Abdominal Compartment Syndrome
The Pediatric Guidelines Sub-Committee for the World Society of the Abdominal Compartment Syndrome
AKAndrew Wallace Kirkpatrick
Andrew Wallace Kirkpatrick
DRDerek J. Roberts
Derek J. Roberts
JWJan J. De Waele
Jan J. De Waele
RJRoman Jaeschke
Roman Jaeschke
COClaudia Olvera
Claudia Olvera
Purpose To update the World Society of the Abdominal Compartment Syndrome (WSACS) consensus definitions and management statements relating to intra-abdominal hypertension (IAH) and the abdominal compartment syndrome (ACS). Methods We conducted systematic or structured reviews to identify relevant studies relating to IAH or ACS. Updated consensus definitions and management statements were then derived using a modified Delphi method and the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) guidelines, respectively. Quality of evidence was graded from high (A) to very low (D) and management statements from strong RECOMMENDATIONS (desirable effects clearly outweigh potential undesirable ones) to weaker SUGGESTIONS (potential risks and benefits of the intervention are less clear). Results In addition to reviewing the consensus definitions proposed in 2006, the WSACS defined the open abdomen, lateralization of the abdominal musculature, polycompartment syndrome, and abdominal compliance, and proposed an open abdomen classification system. RECOMMENDATIONS included intra-abdominal pressure (IAP) measurement, avoidance of sustained IAH, protocolized IAP monitoring and management, decompressive laparotomy for overt ACS, and negative pressure wound therapy and efforts to achieve same-hospital-stay fascial closure among patients with an open abdomen. SUGGESTIONS included use of medical therapies and percutaneous catheter drainage for treatment of IAH/ACS, considering the association between body position and IAP, attempts to avoid a positive fluid balance after initial patient resuscitation, use of enhanced ratios of plasma to red blood cells and prophylactic open abdominal strategies, and avoidance of routine early biologic mesh use among patients with open abdominal wounds. NO RECOMMENDATIONS were possible regarding monitoring of abdominal perfusion pressure or the use of diuretics, renal replacement therapies, albumin, or acute component-parts separation. Conclusion Although IAH and ACS are common and frequently associated with poor outcomes, the overall quality of evidence available to guide development of RECOMMENDATIONS was generally low. Appropriately designed intervention trials are urgently needed for patients with IAH and ACS.

19 June 2018 in World Journal of Emergency Surgery
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Journal Article
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RBRichard P G ten Broek
Richard P G ten Broek
PKPepijn Krielen
Pepijn Krielen
Salomone Di SaverioSalomone Di Saverio
Salomone Di Saverio
ACand Federico Coccolini
and Federico Coccolini
WBWalter L. Biffl
Walter L. Biffl
HGHarry van Goor
Harry van Goor
Adhesive small bowel obstruction (ASBO) is a common surgical emergency, causing high morbidity and even some mortality. The adhesions causing such bowel obstructions are typically the footprints of previous abdominal surgical procedures. The present paper presents a revised version of the Bologna guidelines to evidence-based diagnosis and treatment of ASBO. The working group has added paragraphs on prevention of ASBO and special patient groups. The guideline was written under the auspices of the World Society of Emergency Surgery by the ASBO working group. A systematic literature search was performed prior to the update of the guidelines to identify relevant new papers on epidemiology, diagnosis, and treatment of ASBO. Literature was critically appraised according to an evidence-based guideline development method. Final recommendations were approved by the workgroup, taking into account the level of evidence of the conclusion. Adhesion formation might be reduced by minimally invasive surgical techniques and the use of adhesion barriers. Non-operative treatment is effective in most patients with ASBO. Contraindications for non-operative treatment include peritonitis, strangulation, and ischemia. When the adhesive etiology of obstruction is unsure, or when contraindications for non-operative management might be present, CT is the diagnostic technique of choice. The principles of non-operative treatment are nil per os, naso-gastric, or long-tube decompression, and intravenous supplementation with fluids and electrolytes. When operative treatment is required, a laparoscopic approach may be beneficial for selected cases of simple ASBO. Younger patients have a higher lifetime risk for recurrent ASBO and might therefore benefit from application of adhesion barriers as both primary and secondary prevention. This guideline presents recommendations that can be used by surgeons who treat patients with ASBO. Scientific evidence for some aspects of ASBO management is scarce, in particular aspects relating to special patient groups. Results of a randomized trial of laparoscopic versus open surgery for ASBO are awaited.

10 July 2017 in World Journal of Emergency Surgery
Verified
Journal Article
Open access
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MSMassimo Sartelli
Massimo Sartelli
ACAlain Chichom-Mefire
Alain Chichom-Mefire
FLFrancesco M. Labricciosa
Francesco M. Labricciosa
Timothy Craig HardcastleTimothy Craig Hardcastle
Timothy Craig Hardcastle
FAFikri M Abu-Zidan
Fikri M Abu-Zidan
Fausto CatenaFausto Catena
Fausto Catena
Intra-abdominal infections (IAIs) are common surgical emergencies and have been reported as major contributors to non-trauma deaths in the emergency departments worldwide. The cornerstones of effective treatment of IAIs are early recognition, adequate source control, and appropriate antimicrobial therapy. Prompt resuscitation of patients with ongoing sepsis is of utmost important. In hospitals worldwide, non-acceptance of, or lack of access to, accessible evidence-based practices and guidelines result in overall poorer outcome of patients suffering IAIs. The aim of this paper is to promote global standards of care in IAIs and update the 2013 WSES guidelines for management of intra-abdominal infections.

18 January 2017 in World Journal of Emergency Surgery
Verified
Journal Article
Open access
PDF file
ACand Federico Coccolini
and Federico Coccolini
PSPhilip F. Stahel
Philip F. Stahel
GMGiulia Montori
Giulia Montori
WBWalter Biffl
Walter Biffl
THTal M Horer
Tal M Horer
LALuca Ansaloni
Luca Ansaloni
Complex pelvic injuries are among the most dangerous and deadly trauma related lesions. Different classification systems exist, some are based on the mechanism of injury, some on anatomic patterns and some are focusing on the resulting instability requiring operative fixation. The optimal treatment strategy, however, should keep into consideration the hemodynamic status, the anatomic impairment of pelvic ring function and the associated injuries. The management of pelvic trauma patients aims definitively to restore the homeostasis and the normal physiopathology associated to the mechanical stability of the pelvic ring. Thus the management of pelvic trauma must be multidisciplinary and should be ultimately based on the physiology of the patient and the anatomy of the injury. This paper presents the World Society of Emergency Surgery (WSES) classification of pelvic trauma and the management Guidelines.

18 August 2017 in World Journal of Emergency Surgery
Verified
Journal Article
Open access
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ACand Federico Coccolini
and Federico Coccolini
GMGiulia Montori
Giulia Montori
Fausto CatenaFausto Catena
Fausto Catena
YKYoram Kluger
Yoram Kluger
WBWalter Biffl
Walter Biffl
LALuca Ansaloni
Luca Ansaloni
Spleen injuries are among the most frequent trauma-related injuries. At present, they are classified according to the anatomy of the injury. The optimal treatment strategy, however, should keep into consideration the hemodynamic status, the anatomic derangement, and the associated injuries. The management of splenic trauma patients aims to restore the homeostasis and the normal physiopathology especially considering the modern tools for bleeding management. Thus, the management of splenic trauma should be ultimately multidisciplinary and based on the physiology of the patient, the anatomy of the injury, and the associated lesions. Lastly, as the management of adults and children must be different, children should always be treated in dedicated pediatric trauma centers. In fact, the vast majority of pediatric patients with blunt splenic trauma can be managed non-operatively. This paper presents the World Society of Emergency Surgery (WSES) classification of splenic trauma and the management guidelines.

22 August 2022 in Journal of Ultrasound in Medicine
Verified
Journal Article
Open access
LDLibertario Demi
Libertario Demi
FWFrank Wolfram
Frank Wolfram
CKCatherine Klersy
Catherine Klersy
ASAnnalisa De Silvestri
Annalisa De Silvestri
VFVirginia Valeria Ferretti
Virginia Valeria Ferretti
TPTiziano Perrone
Tiziano Perrone
Following the innovations and new discoveries of the last 10 years in the field of lung ultrasound (LUS), a multidisciplinary panel of international LUS experts from six countries and from different fields (clinical and technical) reviewed and updated the original international consensus for point‐of‐care LUS, dated 2012. As a result, a total of 20 statements have been produced. Each statement is complemented by guidelines and future developments proposals. The statements are furthermore classified based on their nature as technical (5), clinical (11), educational (3), and safety (1) statements.