Background and Aims: Large-scale investigations with longitudinal data on infected native aortic aneurysms (INAAs), a rare but life-threatening emergency, are lacking. The epidemiology, treatment trends, and outcomes of INAAs were investigated in a nationwide population-based cohort. Methods: A total of 2387 hospitalisations for INAAs were identified between 2001 and 2021 in the Taiwanese National Health Insurance Research Database. A retrospective cohort was analysed using data spanning a 21-year study period. In-hospital and post-discharge adverse events, including 1-, 3-, 5- and 10-year mortality, were assessed. Results: The cohort had a mean age of 73.8 ± 11.8 years, with 77.6% being men. There was an increasing trend in INAAs over time, with a high prevalence of comorbid renal insufficiency (53%). Most patients were treated with third-generation cephalosporins and anti-methicillin-resistant Staphylococcus aureus agents. Conservative treatment was associated with the highest mortality rates, including in-hospital death and post-discharge death. The risk of in-hospital mortality was significantly lower in the endovascular aortic repair (EVAR) group compared with the open repair group [odds ratio 0.76, 95% confidence interval (CI): 0.63–0.91]. At the end of follow-up, patients who underwent EVAR demonstrated high mortality risks (hazard ratio 1.13, 95% CI: 1.04–1.23 at the end of follow-up) than open repair. Conclusions: Surgical repair is associated with significantly more favourable post-discharge survival compared with EVAR, underscoring the importance of open repair for optimal management of INAAs. In selected high-risk patients, EVAR may serve as a temporising or palliative option, particularly when definitive open repair is not immediately feasible.

Kimura disease (KD) is a rare, chronic proliferative condition presenting as a subcutaneous mass predominantly located in the head and neck region; it is characterized by eosinophilia and elevated serum IgE levels. IgG4-related disease (IgG4RD) is a fibroinflammatory condition characterized by swelling in single or multiple organs and the infiltration of IgG4 plasma cells. Herein, we presented two cases. Case 1 is a 38-year-old man with a painless mass in his right postauricular region, and Case 2 is a 36-year-old man with painless lymphadenopathy in his bilateral postauricular region. After surgical excision, they showed good recovery with no relapse. Although Cases 1 and 2 shared several overlapping pathological manifestations, there were a few differences that allowed the differentiation of KD and IgG4RD.

Neuropsychiatric systemic lupus erythematous (NPSLE) encompasses various psychiatric and neurological manifestations that develop in patients with systemic lupus erythematous (SLE), secondary to the involvement of the central nervous system (CNS). Although neuropsychiatric manifestations are commonly described in NPSLE, catatonia has been less frequently reported in patients with SLE. The roles of benzodiazepines (BZDs), immunosuppression, therapeutic plasma exchange (TPE), and electroconvulsive therapy (ECT) have all been reported in the management of catatonia. Furthermore, another research reported that catatonic symptoms associated with NPSLE were considerably improved by TPE. We, herein, report a case of catatonia in a patient with newly diagnosed NPSLE who exhibited a favorable prognosis through the early initiation of systemic immunosuppressants and TPE. Furthermore, we have reviewed the literature on the role of medication and plasmapheresis (PP), or TPE, in the treatment of catatonia that is associated with SLE.

Kimura’s disease (KD) is a rare lymphoproliferative fibroinflammatory disorder that commonly affects the subcutaneous tissue and lymph nodes of the head and neck. The condition is a reactive process involving T helper type 2 cytokines. Concurrent malignancies have not been described. Differential diagnosis with lymphoma can be challenging without tissue biopsy. Here, we present the first reported case of coexisting KD and eosinophilic nodular sclerosis Hodgkin lymphoma of the right cervical lymphatics in a 72-year-old Taiwanese man.

Dermatologic immune-related adverse events (dirAEs) are common among cancer patients receiving immune checkpoint inhibitors. These phenomena can | POSTER