Directed palladium-catalyzed C–H functionalisation of C2-amido glycals onto the anomeric position is described as a novel route to C-aryl/alkenylglycosides. An aminoquinoline-type directing group was used to successfully introduce diverse (hetero)aryl and alkenyl groups at position 1 of the sugar (20 examples). Its application to the synthesis of a dapagliflozin analogue is presented.

Palladium catalysis is reported as an efficient tool to afford unique glycoporphyrins via Sonogashira cross-coupling.

First examples of a new class of constrained bicyclic iminosugars have been synthesized by a non-classical Dieckmann-like reaction.

A new mechanism of nitrone epimerizationvia[1,4]-sigmatropic rearrangement was proposed and a set of epimeric iminosugars was synthesized.