Alice Jacquens is a young doctor specializing in anesthesia-intensive care and graduated from Sorbonne University in 2021. She also completed a double scientific curriculum and thus graduated in 2021 with a thesis in Neuroscience at the University of Paris. This work was carried out within the Inserm unit 1141 (Pr. Pierre Gressens), directed by Pr. Vincent Degos on the late post-cranial trauma lesions on a pediatric TBI model. She was thus able to describe the cellular, architectural and behavioral phenomena occurring at the distance of a TBI. She then worked on post-TBI neuroinflammatory phenomena and particularly on microglial reactivity. Through the study of microglial modifications, she was able to identify therapeutic targets. In parallel, Alice Jacquens worked in the neurosurgical intensive care unit of the Pitié-Salpêtrière Hospital and was interested in the long-term outcome of TBI patients both clinically and by diffusion tensor MRI imaging. Through these two approaches, Alice Jacquens has specialized in the post-traumatic brain injury outcome and the development of neuroprotective therapeutic strategies.