Finding new ways to cost-effectively facilitate population screening and improve cancer diagnoses at an early stage supported by data-driven AI models provides unprecedented opportunities to reduce cancer related mortality. This work presents the INCISIVE project initiative towards enhancing AI solutions for health imaging by unifying, harmonizing, and securely sharing scattered cancer-related data to ensure large datasets which are critically needed to develop and evaluate trustworthy AI models. The adopted solutions of the INCISIVE project have been outlined in terms of data collection, harmonization, data sharing, and federated data storage in compliance with legal, ethical, and FAIR principles. Experiences and examples feature breast cancer data integration and mammography collection, indicating the current progress, challenges, and future directions.
1 August 2021 in Journal of Biomedical Informatics
Cancer remains a major global health challenge, affecting diverse populations across various demographics. Integrating Artificial Intelligence (AI) into clinical settings to enhance disease outcome prediction presents notable challenges. This study addresses the limitations of AI-driven cancer care due to low-quality datasets by proposing a comprehensive three-step methodology to ensure high data quality in large-scale cancer-imaging repositories. Our methodology encompasses (i) developing a Data Quality Conceptual Model with specific metrics for assessment, (ii) creating a detailed data-collection protocol and a rule set to ensure data homogeneity and proper integration of multi-source data, and (iii) implementing a Data Integration Quality Check Tool (DIQCT) to verify adherence to quality requirements and suggest corrective actions. These steps are designed to mitigate biases, enhance data integrity, and ensure that integrated data meets high-quality standards. We applied this methodology within the INCISIVE project, an EU-funded initiative aimed at a pan-European cancer-imaging repository. The use-case demonstrated the effectiveness of our approach in defining quality rules and assessing compliance, resulting in improved data integration and higher data quality. The proposed methodology can assist the deployment of big data centralized or distributed repositories with data from diverse data sources, thus facilitating the development of AI tools.
It has been found that most PhD graduates (>85%) do not achieve a long-term academic career and thus there is a growing need to re-imagine PhD education that incentivizes doctoral students to engage with research consumers, not only within their discipline, but also, across other disciplines and sectors to have real social impact for an improved society. The aim of this work is to identify intersectoral/interdisciplinary courses that are considered to broaden student career outside and inside academia. For this purpose, a survey was designed to identify modules which lead to the improvement of students' skills while an analysis of their attributes was also performed. Two target groups have been considered: (a) young researchers and (b) program directors each of which can provide different information regarding the courses of interest. 52 students and 11 directors from 5 European Universities, participated in the study. An absence of such courses in the standard PhD program was observed, while any intersectoral/interdisciplinary activities were conducted outside the PhD program, and organized by collaboration of academia and other organizations. The survey findings reveal the need to restructure the PhD programs.