Several consequences of health effects from municipal solid waste caused by carcinogenic and noncarcinogenic metals have been recognized. The water quality index (WQI) in the groundwater around this landfill is 2945.58, which is unacceptable for consumption. The contaminated groundwater mainly appears within a 1 km radius around the landfill. The metal pollution levels in the soil in descending order were Cu > Cd > Zn=Cr > Pb > Ni. The pollution degree (ER) of Cd was 2898.88, and the potential ecological risk index (RI) was 2945.58, indicating that the risk level was very high. Surprisingly, the hazard index (HI) of Pb (2.05) and Fe (1.59) in children was higher than 1. This indicated that the chronic risk and cancer risk caused by Pb and Fe for children were at a medium level. Carcinogenic risk by oral (CR oral) consumption of Ni, Cd, and Cr in children was 1.4E − 04, 2.5E − 04, and 1.8E − 04, respectively, while the lifetime carcinogenic risk (LCR) of Ni, Cd, and Cr in children was 1.5E − 04, 2.8E − 04, and 2.0E − 04, respectively. In adults, CR oral of Ni and Cr were 1.6E − 03 and 3.0E − 04, respectively, while LCR of Ni and Cr were 1.6E − 03 and 3.4E − 04, respectively, which exceeded the carcinogenic risks limits. Our study indicated a lifetime carcinogenic risk to humans. Environmental surveillance should focus on reducing health risks such as continuous monitoring of the groundwater, soil, and leachate treatment process.

Heavy metals leaching from municipal solid waste landfills have resulted in severe environmental pollution and may influence human health status. This study aimed to determine the total concentrations of metals, environmental risk and evaluate the potential human health risk including non-carcinogenic and carcinogenic effects. Soil samples were collected from the open municipal solid waste landfill located in central, Thailand. The 90^th percentile concentration of Bi, Cd, Co, Cr, Cu, Li, Ni, Pb, and Zn were above the world soil average. The pollution load index revealed significant contamination by multiple elements. The soil was extremely contaminated by Bi, heavily contaminated by Cd, and moderately contaminated by Cu. The potential ecological risk demonstrated that Cd was the dominant leading risk, followed by Cu. Long term exposure to the soil causing adverse health effects related to non-carcinogenic in both children (HI = 1.73) and adults (HI = 1.21). The lifetime carcinogenic risks for children and adults indicated an acceptable risk (2.6x10⁻⁵ for children and 1.6x10⁻⁵ for adults) where Cr was the leading factor. Long term monitoring of heavy metals concentration in landfill and adjacent paddy fields together with enhancing occupational safety and health awareness to reduce exposure to heavy metal as the potential hazard should be considered.

Gold-mining activities have been demonstrated to result in significant environmental pollution by Hg, Pb, and Mn, causing serious concerns regarding the potential threat to the public health of neighboring populations around the world. The present study focused on heavy-metal contamination in the eggs, blood, feed, soil, and drinking water on chicken farms, duck farms, and free-grazing duck farms located in areas < 25 km and > 25 km away from a gold mine in northern Thailand. In an area < 25 km away, Hg, Pb, and Mn concentrations in the eggs of free-grazing ducks were significantly higher than > 25 km away (p < 0.05). In blood, Hg concentration in free-grazing ducks was also significantly higher than those in an area > 25 km away (p < 0.05). Furthermore, the Pb concentration in the blood of farm ducks was significantly higher than in an area > 25 km away (p < 0.05). The concentration of Cd in drinking water on chicken farms was significantly higher for farms located within 25 km of the gold mine (p < 0.05). Furthermore, a high correlation was shown between the Pb (r² = 0.84) and Cd (r² = 0.42) found between drinking water and blood in free-grazing ducks in the area < 25 km away. Therefore, health risk from heavy-metal contamination was inevitably avoided in free-grazing activity near the gold mine. The incremental lifetime cancer risk (ILCR) in the population of both Pb and Cd exceeded the cancer limit (10⁻⁴) for all age groups in both areas, which was particularly high in the area < 25 km for chicken-egg consumption, especially among people aged 13–18 and 18–35 years old. Based on these findings, long-term surveillance regarding human and animal health risk must be strictly operated through food chains and an appropriate control plan for poultry businesses roaming around the gold mine.

Zoonotic pathogens such as arboviruses have comprised a significant proportion of emerging infectious diseases in humans. The role of wildlife species as reservoirs for arboviruses is poorly understood, especially in endemic areas such as Southeast Asia. This study aims to determine the exposure history of different macaque species from national parks in Thailand to mosquito-borne flaviviruses and alphavirus by testing the serum samples collected from 25 northern pigtailed macaques, 33 stump-tailed macaques, and 4 long-tailed macaques for the presence of antibodies against dengue, Zika, and chikungunya viruses by plaque reduction neutralization assay. Specific neutralizing antibodies against Dengue virus (DENV1-4) and Zika virus (ZIKV) were mainly found in stump-tailed macaques, whereas neutralizing antibody titers were not detected in long-tailed macaques and pigtailed macaques as determined by 90% plaque reduction neutralization assay (PRNT90). One long-tailed macaque captured from the south of Thailand exhibited antibody titers against chikungunya virus (CHIKV), suggesting enzootic of this virus to nonhuman primates (NHPs) in Thailand. Encroachment of human settlements into the forest has increased the interface that exposes humans to zoonotic pathogens such as arboviruses found in monkeys. Nonhuman primates living in different regions of Thailand showed different patterns of arboviral infections. The presence of neutralizing antibodies among wild monkeys in Thailand strongly suggests the existence of sylvatic cycles for DENV, ZIKV, and CHIKV in Thailand. The transmission of dengue, Zika, and chikungunya viruses among wild macaques may have important public health implications.