With the improvement of economic conditions and the increase in living standards, people’s attention in regard to health is also continuously increasing. They are beginning to place their hopes on machines, expecting artificial intelligence (AI) to provide a more humanized medical environment and personalized services, thus greatly expanding the supply and bridging the gap between resource supply and demand. With the development of IoT technology, the arrival of the 5G and 6G communication era, and the enhancement of computing capabilities in particular, the development and application of AI-assisted healthcare have been further promoted. Currently, research on and the application of artificial intelligence in the field of medical assistance are continuously deepening and expanding. AI holds immense economic value and has many potential applications in regard to medical institutions, patients, and healthcare professionals. It has the ability to enhance medical efficiency, reduce healthcare costs, improve the quality of healthcare services, and provide a more intelligent and humanized service experience for healthcare professionals and patients. This study elaborates on AI development history and development timelines in the medical field, types of AI technologies in healthcare informatics, the application of AI in the medical field, and opportunities and challenges of AI in the field of medicine. The combination of healthcare and artificial intelligence has a profound impact on human life, improving human health levels and quality of life and changing human lifestyles.

Bone malignant tumors are metastatic and aggressive, with poor treatment outcomes and prognosis. Rapid and accurate diagnosis is crucial for limb salvage and increasing the survival rate. There is a lack of research on deep learning to segment bone malignant tumor lesions in medical images with complex backgrounds and blurred boundaries. Therefore, we propose a new intelligent auxiliary framework for the medical image segmentation of bone malignant tumor lesions, which consists of a supervised edge-attention guidance segmentation network (SEAGNET). We design a boundary key points selection module to supervise the learning of edge attention in the model to retain fine-grained edge feature information. We precisely locate malignant tumors by instance segmentation networks while extracting feature maps of tumor lesions in medical images. The rich contextual-dependent information in the feature map is captured by mixed attention to better understand the uncertainty and ambiguity of the boundary, and edge attention learning is used to guide the segmentation network to focus on the fuzzy boundary of the tumor region. We implement extensive experiments on real-world medical data to validate our model. It validates the superiority of our method over the latest segmentation methods, achieving the best performance in terms of the Dice similarity coefficient (0.967), precision (0.968), and accuracy (0.996). The results prove the important contribution of the framework in assisting doctors to improve the accuracy of diagnosis and clinical efficiency.

Osteosarcoma is a malignant tumor derived from primitive osteogenic mesenchymal cells, which is extremely harmful to the human body and has a high mortality rate. Early diagnosis and treatment of this disease is necessary to improve the survival rate of patients, and MRI is an effective tool for detecting osteosarcoma. However, due to the complex structure and variable location of osteosarcoma, cancer cells are highly heterogeneous and prone to aggregation and overlap, making it easy for doctors to inaccurately predict the area of the lesion. In addition, in developing countries lacking professional medical systems, doctors need to examine mass of osteosarcoma MRI images of patients, which is time-consuming and inefficient, and may result in misjudgment and omission. For the sake of reducing labor cost and improve detection efficiency, this paper proposes an Attention Condenser-based MRI image segmentation system for osteosarcoma (OMSAS), which can help physicians quickly locate the lesion area and achieve accurate segmentation of the osteosarcoma tumor region. Using the idea of AttendSeg, we constructed an Attention Condenser-based residual structure network (ACRNet), which greatly reduces the complexity of the structure and enables smaller hardware requirements while ensuring the accuracy of image segmentation. The model was tested on more than 4000 samples from two hospitals in China. The experimental results demonstrate that our model has higher efficiency, higher accuracy and lighter structure for osteosarcoma MRI image segmentation compared to other existing models.

Histopathological examination is an important criterion in the clinical diagnosis of osteosarcoma. With the improvement of hardware technology and computing power, pathological image analysis systems based on artificial intelligence have been widely used. However, classifying numerous intricate pathology images by hand is a tiresome task for pathologists. The lack of labeling data makes the system costly and difficult to build. This study constructs a classification assistance system (OHIcsA) based on active learning (AL) and a generative adversarial network (GAN). The system initially uses a small, labeled training set to train the classifier. Then, the most informative samples from the unlabeled images are selected for expert annotation. To retrain the network, the final chosen images are added to the initial labeled dataset. Experiments on real datasets show that our proposed method achieves high classification performance with an AUC value of 0.995 and an accuracy value of 0.989 using a small amount of labeled data. It reduces the cost of building a medical system. Clinical diagnosis can be aided by the system’s findings, which can also increase the effectiveness and verifiable accuracy of doctors.

Malignant tumors are a common cytopathologic disease. Pathological tissue examination is a key tool for diagnosing malignant tumors. Doctors need to manually analyze the images of pathological tissue sections, which is not only time-consuming but also highly subjective, easily leading to misdiagnosis. Most of the existing computer-aided diagnostic techniques focus too much on accuracy when processing pathological tissue images, and do not take into account the problems of insufficient resources in developing countries to meet the training of large models and the difficulty of obtaining medical annotation data. Based on this, this study proposes an artificial intelligence multiprocessing scheme (MSPInet) for digital pathology images of malignant tumors. We use techniques such as data expansion and noise reduction to enhance the dataset. Then we design a coarse segmentation method for cell nuclei of pathology images based on Transformer for Semantic Segmentation and further optimize the segmentation of tumor edges using conditional random fields. Finally, we improve the training strategy for knowledge distillation. As a medical assistive system, the method can quantify and convert complex pathology images into analyzable image information. Experimental results show that our method performs well in terms of segmentation accuracy and also has advantages in terms of time and space efficiency. This makes our technology available to developing countries that are not as well resourced, and equipped in terms of medical care. The teacher model and lightweight student model included in our method achieve 71.6% and 66.1% Intersection over Union (IoU) in cell segmentation respectively, outperforming Swin-unet and CSWin Transformer.

The analysis and interpretation of cytopathological images are crucial in modern medical diagnostics. However, manually locating and identifying relevant cells from the vast amount of image data can be a daunting task. This challenge is particularly pronounced in developing countries where there may be a shortage of medical expertise to handle such tasks. The challenge of acquiring large amounts of high-quality labelled data remains, many researchers have begun to use semi-supervised learning methods to learn from unlabeled data. Although current semi-supervised learning models partially solve the issue of limited labelled data, they are inefficient in exploiting unlabeled samples. To address this, we introduce a new AI-assisted semi-supervised scheme, the Reliable-Unlabeled Semi-Supervised Segmentation (RU3S) model. This model integrates the ResUNet-SE-ASPP-Attention (RSAA) model, which includes the Squeeze-and-Excitation (SE) network, Atrous Spatial Pyramid Pooling (ASPP) structure, Attention module, and ResUNet architecture. Our model leverages unlabeled data effectively, improving accuracy significantly. A novel confidence filtering strategy is introduced to make better use of unlabeled samples, addressing the scarcity of labelled data. Experimental results show a 2.0% improvement in mIoU accuracy over the current state-of-the-art semi-supervised segmentation model ST, demonstrating our approach’s effectiveness in solving this medical problem.