A pulsed 55-MeV race-track microtron that was developed and constructed jointly at the Skobeltsyn Institute of Nuclear Physics, Moscow State University and the Lebedev Physical Institute with the...
In our work, the photonuclear production of 198,199Au isotopes for nuclear medicine purposes was studied, and a method for their recovery from irradiated mercury was developed. The yields of the corresponding nuclear reactions were determined, and a comparison of various methods of obtaining gold radioisotopes was provided. New sorbents based on benzo-15-crown-5, which selectively binds gold, were studied, and the optimal conditions for Au recovery with a high degree of purification from mercury were found. It was established that, for the fast and quantitative recovery of Au isotopes, it was necessary to add at least 0.1 mg of the carrier. As a result, the developed method can be regularly used to obtain 198,199Au for the research of radiopharmaceuticals based on them.
A new method of production of one of the most widely used isotopes in nuclear medicine, 177Lu, with high chemical purity was developed; this method includes irradiation of the HfO2 target with bremsstrahlung photons. The irradiated target was dissolved in HF and then diluted and placed onto a column filled with LN resin. Quantitative sorption of 177Lu could be observed during this process. The column later was rinsed with the mixture of 0.1 M HF and 1 M HNO3 and then 2 M HNO3 to remove impurities. Quantitative desorption of 177Lu was achieved by using 6 M HNO3. The developed method of 177Lu production ensures high purification of this isotope from macroquantities of hafnium and zirconium and radioactive impurities of carrier-free yttrium. The content of 177mLu in 177Lu in photonuclear production was determined. Due to high chemical and radionuclide purity, 177Lu obtained by the developed method can be used in nuclear medicine.
Nowadays, cobalt isotopes 55Co, 57Co, and 58mCo are considered to be promising radionuclides in nuclear medicine, with 55Co receiving the most attention as an isotope for diagnostics by positron emission tomography. One of the current research directions is dedicated to its production using electron accelerators (via photonuclear method). In our work, the yields of nuclear reactions occurring during the irradiation of natNi and 60Ni by bremsstrahlung photons with energy up to 55 MeV were determined. A method of fast and simple cobalt isotopes separation from irradiated targets using extraction chromatography was developed.
We consider three types of electron accelerators that can be used for various applications, such as industrial, medical, cargo inspection, and isotope production applications, and that require small- and medium-sized machines, namely classical microtron (CM), race-track microtron (RTM), and multisection linac. We review the principles of their operation, the specific features of the beam dynamics in these machines, discuss their advantages and weak points, and compare their technical characteristics. In particular, we emphasize the intrinsic symmetry of the stability region of microtrons. We argue that RTMs can be a preferable choice for medium energies (up to 100 MeV) and that the range of their potential applications can be widened, provided that the beam current losses are significantly reduced. In the article, we analyze two possible solutions in detail, namely increasing the longitudinal acceptance of an RTM using a higher-order harmonic accelerating structure and improving beam matching at the injection.
1 January 2020 in Moscow University Physics Bulletin
The back-bombardment effect is studied based on the example of the 10 MeV standing wave technological electron linac. The beam dynamics is calculated, the