The purpose of the present study was to examine whether a visual stimuli program during soccer training can affect reaction time (RT), cognitive function, and physical fitness in adolescent soccer players. Thirty-eight male soccer players aged 10–15 were randomly assigned to either the intervention (Group A) or the control group (Group B). At baseline and at the end of the 6-month study FITLIGHT Trainer, the Cognitive Function Scanner Mobile Test Suite, a Virtual Reality (VR) game, and the ALPHA—Fitness and the Eurofit test batteries were used to measure participants’ abilities. After the baseline assessment, Group A followed their regular soccer training combined with a visual stimuli program, while Group B continued their regular soccer training program alone for 6 months. At the end of the 6-month study, Group A showed statistically significant improvements in simple RT by 11.8% (p = 0.002), repeated sprints by 13.4% (p ≤ 0.001), and Pen-to-Point Cognitive Function by 71.62% (p < 0.001) and 72.51% for dominant and non-dominant hands, respectively. However, a between-groups analysis showed that there was no statistically significant difference between the two groups in most of the measurements studied. In conclusion, a visual stimuli training program does not seem to add any value to the traditional soccer training program for adolescents. Nevertheless, this study helps to underline the potential of newly emerging technology as a tool for the assessment of RT.

Purpose: To examine the neuroprotective action of citicoline in the treatment of glaucoma and glaucoma phacoemulsified patients.Methods: Fifty‐nine patients (118 eyes) with glaucoma were included in the study. Intraocular pressure (IOP) level <25 mmHg with or without treatment was the inclusion criterion. Thirty‐three patients received citicoline eye drops three times per day for 3 months and 26 received hyaluronic Na eyedrops, respectively. During the 3 months study all the patients underwent pachymetry and repeatedly IOP measurements, Visual Field Tests (VFT), Schirmer’s tests and OCT examination. Statistical analyses performed between the two groups, including further parameters, such as the severity of IOP, the visual field defects (MD value) and the presence of IOL.Results: In patients with IOP < 15 mmHg, the citicoline group (n = 14) showed improved PSD value compared to hyaluronic Na group (n = 12; p = 0.003). In the 15–20 mmHg IOP patients, no changes noticed. In patients with 20 mmHg< IOP < 25 mmHg, the citicoline group (n = 10) showed higher RNFL (94.3 ± 11.2 μm) compared to hyaluronic Na group (n = 11, RNFL = 83.2 ± 11.7 μm; p = 0.029). In 16 eyes of the citicoline group, the RNFL appeared improved in the IOL eyes (p = 0.026).There were no statistical differences between the two groups regarding the severity of glaucoma, using the MD index in VFT.Conclusion: Citicoline seems to act advantageously towards the RNFL index in the IOP > 20 mmHg and phacoemulsified patients, as well as the PSD index in patients with IOP < 15 mmHg.