Shortage of potable water is a global problem, and this problem can be met by searching new areas where groundwater is available. GIS is an effective and necessary tool to identify groundwater potential zones in an area. In the present study, groundwater potential zones (GWPZs) were identified in the Kangsabati River basin of east India having an area of about 6488 km²using multi-criteria decision analysis (MCDA) and analytical hierarchy process (AHP). The criteria like geology, geomorphology, elevation, slope, drainage, lineament, curvature, topographic wetness, land use/land cover, and soil were extracted from satellite data and the weights for each parameter and its sub-parameters were assigned through analytical hierarchy process based on their respective relevance as influencing factors for groundwater recharge. Very low, low, moderate, high, and very high groundwater potentiality represent 28.93%, 30.56%, 19.75%, 14.62%, and 6.11% area, respectively. The low-lying flat plains of the southeastern section, as well as the centrally located dam, are ideal for groundwater recharge, while the upland plain of the northwestern part, with its hard rock terrain, is less so. This outcome has been verified using pre-monsoon and post-monsoon groundwater depth data, indicating that the strategy is most appropriate for this region. Thus, the groundwater potential zone maps remain very useful for conducting extensive ground-based hydrogeological studies that facilitate the identification of suitable bore well/dug well sites.